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Change from originator infliximab to biosimilar does not affect 1-year outcome in children with inflammatory bowel disease
Publication Year: 2024 Source: JPGN Rep PMID: 39610440 DOI: 10.1002/jpr3.12134
OBJECTIVES: Payer mandates have resulted in children with inflammatory bowel disease (IBD) switching from originator Remicade(R) (O-Rem) to an infliximab biosimilar (B-IFX). Patients and families are fearful of switching because disease has been well controlled on O-Rem. Real-world data documenting clinical outcomes after such switches in pediatric patients are limited. …
Unveiling the intricacies of irritable bowel syndrome
Publication Year: 2024 Source: World J Gastroenterol PMID: 39610774
No Abstract
Navigating the complexities of perianal Crohn's disease: Diagnostic strategies, treatment approaches, and future perspectives
Publication Year: 2024 Source: World J Gastroenterol PMID: 39610776
No Abstract
Diagnostic delay in inflammatory bowel disease: Current situation and problems
Publication Year: 2024 Source: World J Gastroenterol PMID: 39610777 DOI: 10.3748/wjg.v30.i44.4738
In this article, we comment on the article by Bluthner et al published recently. Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a chronic relapsing and remitting condition primarily as a consequence of intestinal inflammation. It is important about adopting early and effective treatment to control clinical …
Dye-based chromoendoscopy versus i-scan virtual chromoendoscopy in long-standing ulcerative colitis: Multicenter prospective RCT
Publication Year: 2024 Source: Endosc Int Open PMID: 39610949
No Abstract
Akkermansia muciniphila - impact on the cardiovascular risk, the intestine inflammation and obesity
Publication Year: 2024 Source: Acta Biochim Pol PMID: 39611203
No Abstract
Targeting mucosal healing in Crohn's disease: efficacy of novel pathways and therapeutic targets
Publication Year: 2024 Source: Expert Opin Ther Targets PMID: 39611536
No Abstract
Peptostreptococcus Anaerobius enhances dextran sulfate sodium-induced colitis by promoting nf-κB-NLRP3-Dependent macrophage pyroptosis
Publication Year: 2024 Source: Virulence PMID: 39611567
No Abstract
Mesh-related complications and recurrence after incisional hernia repair in patients with fistulizing versus non-fistulizing Crohn's disease
Publication Year: 2024 Source: Hernia PMID: 39611992
No Abstract
Downregulated KLF4, induced by m6A modification, aggravates intestinal barrier dysfunction in inflammatory bowel disease
Publication Year: 2024 Source: Cell Mol Life Sci PMID: 39612002 DOI: 10.1007/s00018-024-05514-7
BACKGROUND: Kruppel-like factor 4 (KLF4), a transcription factor, is involved in various biological processes. However, the role of KLF4 in regulating the intestinal epithelial barrier (IEB) in inflammatory bowel disease (IBD) and its mechanism have not been extensively studied. METHODS: KLF4 expression in IBD patients and colitis mice was analyzed …
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