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Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells

Publication Year: 2024 Source: Nat Commun PMID: 39632879

No Abstract

Crohn's disease after multiple doses of rituximab treatment in a child with refractory nephrotic syndrome and an ATG2A mutation: a case report

Publication Year: 2024 Source: Front Pediatr PMID: 39633821 DOI: 10.3389/fped.2024.1464757

De novo inflammatory bowel disease (IBD) in response to rituximab (RTX) has been documented on multiple occasions as a severe adverse effect. However, none of these reports mentioned any genetic variation associated with this complication. We describe the case of a 16-year-old patient with refractory nephrotic syndrome (NS) diagnosed at …

Dissecting Innate and Adaptive Immunity in Inflammatory Bowel Disease: Immune Compartmentalization, Microbiota Crosstalk, and Emerging Therapies

Publication Year: 2024 Source: J Inflamm Res PMID: 39634289 DOI: 10.2147/JIR.S492079

The intestinal immune system is the largest immune organ in the human body. Excessive immune response to intestinal cavity induced by harmful stimuli including pathogens, foreign substances and food antigens is an important cause of inflammatory diseases such as celiac disease and inflammatory bowel disease (IBD). Although great progress has …

Unusual Presentation of Crohn's Disease: Distal transverse colon mass

Publication Year: 2024 Source: Sultan Qaboos Univ Med J PMID: 39634807

No Abstract

Mendelian randomization reveals predictive, preventive, and personalized insights into inflammatory bowel disease: the role of gut microbiome and circulating inflammatory proteins

Publication Year: 2024 Source: EPMA J PMID: 39635016 DOI: 10.1007/s13167-024-00384-2

BACKGROUND: A chronic illness with increasing global frequency, inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's disease (CD), profoundly affects patients' quality of life and healthcare systems. IBD pathogenesis consists of changes in gut microbiota, immune system dysregulation, and genetic predisposition. Although emerging data suggests that gut …

Corticosteroids combined with infliximab vs. corticosteroids sequential infliximab for acute severe ulcerative colitis with mucosal deficiency: a retrospective study

Publication Year: 2024 Source: Front Med (Lausanne) PMID: 39635590

No Abstract

Association between inflammatory bowel disease and erythema nodosum: a two-sample mendelian randomization study

Publication Year: 2024 Source: Arch Dermatol Res PMID: 39636340

No Abstract

Childhood developmental environment affects adult intestinal inflammation levels: preliminary evidence from older adults in the United States

Publication Year: 2024 Source: Ann Hum Biol PMID: 39638766

No Abstract

Altered plasma levels of the SARS-CoV-2-related proteins ACE2 and TMPRSS2 in patients with Crohn's disease

Publication Year: 2024 Source: Sci Rep PMID: 39638806

No Abstract

Toll-like receptor 3 signaling attenuated colitis-associated cancer development in mice

Publication Year: 2024 Source: Sci Rep PMID: 39639064

No Abstract

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