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Exploring the efficacy of Transcutaneous Auricular Vagus nerve stimulation (taVNS) in modulating local and systemic inflammation in experimental models of colitis
Publication Year: 2024 Source: Bioelectron Med PMID: 39648211 DOI: 10.1186/s42234-024-00162-5
BACKGROUND: Current inflammatory bowel disease (IBD) treatments often fail to achieve lasting remission and have adverse effects. Vagus nerve stimulation (VNS) offers a promising therapy due to its anti-inflammatory effects. Its invasive nature, however, has led to the development of non-invasive methods like transcutaneous auricular VNS (taVNS). This study assesses …
Sulfasalazine-Loaded Copper-Tannic Acid Coordination Nanozyme Enables ROS Scavenging and Immunomodulation for Inflammatory Bowel Disease Therapy
Publication Year: 2024 Source: Adv Healthc Mater PMID: 39648654 DOI: 10.1002/adhm.202403738
Inflammatory bowel disease (IBD) is associated with elevated levels of reactive oxygen species (ROS) and an increased expression of proinflammatory cytokines. Anti-inflammatory drugs, monoclonal antibodies, and immunomodulators are commonly employed to control the inflammatory response in the management of IBD. Here, a copper and tannic acid (TA) coordination nanozyme (CuTA) …
Establishment of a surveillance program for anal cancer in Crohn's disease
Publication Year: 2024 Source: World J Gastroenterol PMID: 39649548
No Abstract
Statin exposure and risk of colorectal cancer in patients with inflammatory bowel disease: a systematic review and meta-analysis
Publication Year: 2024 Source: Front Med (Lausanne) PMID: 39650188 DOI: 10.3389/fmed.2024.1507739
BACKGROUND: While epidemiological studies have linked statin use to a reduced risk of advanced colorectal adenomas, its impact on colorectal cancer (CRC) risk in patients with inflammatory bowel disease (IBD) remains unclear. To our knowledge, no meta-analysis to date has specifically examined this association. Therefore, we conducted a systematic review …
Global and regional genetic association analysis of ulcerative colitis and type 2 diabetes mellitus and causal validation analysis of two-sample two-way Mendelian randomization
Publication Year: 2024 Source: Front Immunol PMID: 39650653
No Abstract
High-Intensity Laser Therapy - An Option for Managing the Pain in Anal Fissures
Publication Year: 2024 Source: J Lasers Med Sci PMID: 39650782
No Abstract
Enteropathic SAPHO Syndrome in Ulcerative Colitis Responsive to Bisphosphonates
Publication Year: 2024 Source: Case Rep Rheumatol PMID: 39651400 DOI: 10.1155/2024/3558853
SAPHO syndrome, a rare inflammatory disorder of bone, joints, and skin, is named based on the presence of synovitis, acne, pustulosis, hyperostosis, and osteitis. The hallmark of SAPHO syndrome includes osteoarticular and dermatologic manifestations, however, rarer associations with inflammatory bowel disease (particularly Crohn's disease) have been documented. The literature on …
Early Biologic Treatment for Inflammatory Bowel Disease: Drugs
Publication Year: 2024 Source: Early Biologic Treatment for Inflammatory Bowel Disease: Drugs PMID: 39652700
No Abstract
Modulation of CB1 and CB2 receptors and endocannabinoid activity in inflammatory bowel diseases
Publication Year: 2024 Source: J Physiol Pharmacol PMID: 39652903 DOI: 10.26402/jpp.2024.5.08
The endocannabinoid system (ECS) and nociceptin receptor (NOP) have been implicated in the pathology of inflammatory bowel diseases (IBD) mediating pain and alleviating inflammation. In this study we searched for the possible activation of ECS and NOP system and the correlation between CB1, CB2 and NOP receptors in IBD patients. …
Pyoderma Gangrenosum: A Retrospective Case Series of 44 Patients
Publication Year: 2024 Source: Dermatol Pract Concept PMID: 39652952
No Abstract
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