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Clinical study of Jianpi Qingchang decoction in the treatment of ulcerative colitis patients with spleen deficiency and dampness-heat syndrome accompanied by fatigue: Study protocol for a randomized controlled trial
Publication Year: 2024 Source: Contemp Clin Trials Commun PMID: 39735170 DOI: 10.1016/j.conctc.2024.101409
BACKGROUND: Ulcerative colitis (UC) is a chronic non-specific inflammatory intestinal disease, categoried under "dysentery" and "intestinal bleeding" in Traditional Chinese Medicine (TCM). Jianpi Qingchang decoction (JPQC) is a combination formula specifically designed for the treatment of UC. The primary objective of this study is to examine the clinical efficacy of …
Advancing early diagnosis of inflammatory bowel disease: A call for enhanced efforts
Publication Year: 2024 Source: World J Gastroenterol PMID: 39735269 DOI: 10.3748/wjg.v30.i48.5191
The diagnosis of inflammatory bowel disease (IBD) is complicated by its nonspecific clinical presentation and the limited accuracy of existing biomarker tests, frequently resulting in significant delays from the time of symptom onset to the achievement of a definitive diagnosis. Thus, improving the early identification of IBD remains a crucial …
Role of Candida species in pathogenesis, immune regulation, and prognostic tools for managing ulcerative colitis and Crohn's disease
Publication Year: 2024 Source: World J Gastroenterol PMID: 39735273 DOI: 10.3748/wjg.v30.i48.5212
The gut microbiome plays a key role in the pathogenesis and disease activity of inflammatory bowel disease (IBD). While research has focused on the bacterial microbiome, recent studies have shifted towards host genetics and host-fungal interactions. The mycobiota is a vital component of the gastrointestinal microbial community and plays a …
CD8+ cell dominance in immune checkpoint inhibitor-induced colitis and its heterogeneity across endoscopic features
Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 39735350 DOI: 10.1177/17562848241309445
BACKGROUND: Immune checkpoint inhibitor (ICI)-induced colitis is a significant adverse event associated with ICI therapy, known to be linked to increased cytotoxic T-cell activity. OBJECTIVES: To compare T-cell subsets based on the endoscopic features of ICI-induced colitis and to compare these findings with those of inflammatory bowel disease (IBD). DESIGN: …
Water-assisted colonoscopy in inflammatory bowel diseases: From technical implications to diagnostic and therapeutic potentials
Publication Year: 2024 Source: World J Gastrointest Endosc PMID: 39735395 DOI: 10.4253/wjge.v16.i12.647
Water-assisted colonoscopy (WAC) application in inflammatory bowel diseases (IBD) endoscopy offers significant technical opportunities. Traditional gas-aided insufflation colonoscopy increases patient discomfort, presenting challenges in the frequent and detailed mucosal assessments required for IBD endoscopy. WAC techniques, including water immersion and exchange, provide superior patient comfort and enhanced endoscopic visualisation. WAC …
Effect of commercial prescription diets containing prebiotics on clinical signs and fecal microbiome in dogs with intestinal disease
Publication Year: 2024 Source: Pol J Vet Sci PMID: 39736034
No Abstract
A comparative approach on the prophylactic impact of fermented beverages on acute ulcerative colitis in mouse model
Publication Year: 2024 Source: Pol J Vet Sci PMID: 39736035
No Abstract
Fatigue, pain and faecal incontinence in adult inflammatory bowel disease patients and the unmet need: a national cross-sectional survey
Publication Year: 2024 Source: BMC Gastroenterol PMID: 39736517 DOI: 10.1186/s12876-024-03570-8
BACKGROUND AND AIMS: The co-existence of fatigue, pain and faecal incontinence in people with Inflammatory Bowel Disease (IBD) is unknown. We aimed to determine the presence of and relationship between these symptoms and patients' desire for intervention. METHODS: Adults with IBD in the UK, recruited from clinics, the national IBD-BioResource, …
Health-care resource use and costs associated with inflammatory bowel disease in northwest London: a retrospective linked database study
Publication Year: 2024 Source: BMC Gastroenterol PMID: 39736541 DOI: 10.1186/s12876-024-03559-3
BACKGROUND: With 20-40% of patients who have inflammatory bowel disease (IBD) not responding to therapy, resource use and costs can be high. We performed a descriptive analysis of health-care data for IBD management in the National Health Service to explore potential areas for improvement. METHODS: In this exploratory study, we …
Predictive modeling to evaluate long-term treatment effectiveness of darvadstrocel in patients with complex perianal fistulas in Crohn's disease
Publication Year: 2024 Source: BMC Gastroenterol PMID: 39736547
No Abstract
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