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Leucine-Enriched Diet Reduces Fecal MPO but Does Not Protect Against DSS Colitis in a Mouse Model of Crohn's Disease-like Ileitis

Publication Year: 2024 Source: Int J Mol Sci PMID: 39519299 DOI: 10.3390/ijms252111748

Understanding the complex link between inflammation, gut health, and dietary amino acids is becoming increasingly important in the pathophysiology of inflammatory bowel disease (IBD). This study tested the hypothesis that a leucine-rich diet could attenuate inflammation and improve gut health in a mouse model of IBD. Specifically, we investigated the …

Mechanisms of Action of Exclusive Enteral Nutrition and Other Nutritional Therapies in Crohn's Disease

Publication Year: 2024 Source: Nutrients PMID: 39519414 DOI: 10.3390/nu16213581

BACKGROUND AND OBJECTIVES: Crohn's disease (CD) is an inflammatory bowel disease (IBD) characterized by transmural inflammation and intestinal fibrosis involving mostly the small intestine and colon. The pathogenic mechanisms of CD remain incompletely understood and cures are unavailable. Current medical therapies are aimed at inducing prolonged remission. Most of the …

Selenium, Immunity, and Inflammatory Bowel Disease

Publication Year: 2024 Source: Nutrients PMID: 39519453 DOI: 10.3390/nu16213620

Dietary intervention is a subject of growing interest in the management of inflammatory bowel disease (IBD), as new incident cases across the globe are rapidly rising, suggesting environmental factors as contributing elements. Dietary components and micronutrients have been associated with IBD pathogenesis or reductions in disease severity. Selenium, a diet-derived …

Phytochemical Compounds as Promising Therapeutics for Intestinal Fibrosis in Inflammatory Bowel Disease: A Critical Review

Publication Year: 2024 Source: Nutrients PMID: 39519465 DOI: 10.3390/nu16213633

BACKGROUND/OBJECTIVE: Intestinal fibrosis, a prominent consequence of inflammatory bowel disease (IBD), presents considerable difficulty owing to the absence of licensed antifibrotic therapies. This review assesses the therapeutic potential of phytochemicals as alternate methods for controlling intestinal fibrosis. Phytochemicals, bioactive molecules originating from plants, exhibit potential antifibrotic, anti-inflammatory, and antioxidant activities, …

Use of Complementary and Alternative Medicine by Greek Patients with Inflammatory Bowel Disease

Publication Year: 2024 Source: Nutrients PMID: 39519512 DOI: 10.3390/nu16213679

BACKGROUND AND OBJECTIVES: Complementary and alternative medicine (CAM) is regularly used by several patients with inflammatory bowel disease (IBD) in many countries. Data concerning the use of CAM in Greek patients with IBD are lacking. This study aimed to determine the prevalence and indicators of CAM use in Greek IBD …

The Therapeutic Effects of Lactic Acid Bacteria Isolated from Spotted Hyena on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice

Publication Year: 2024 Source: Nutrients PMID: 39519515 DOI: 10.3390/nu16213682

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic condition characterized by recurrent episodes and an unclear etiology. Given the limitations of current therapeutic options, which include suboptimal efficacy and significant side effects, there is a pressing need to explore novel treatments. Probiotics derived from diverse species have been identified as …

Functional Foods in Preventing Human Blood Platelet Hyperactivity-Mediated Diseases-An Updated Review

Publication Year: 2024 Source: Nutrients PMID: 39519549

No Abstract

Food Insecurity Is Common in Patients with Inflammatory Bowel Disease and Is Associated with Increased Ultra-Processed Food Intake

Publication Year: 2024 Source: Nutrients PMID: 39519570 DOI: 10.3390/nu16213736

BACKGROUND/OBJECTIVES: Food insecurity (FI) is defined as the lack of consistent access to enough food for an active and healthy life. FI affects over 30 million Americans and is associated with poor clinical outcomes and impaired quality of life and drives significant health inequities. Despite the rising prevalence of FI …

Micronutrient Deficiency and Muscular Status in Inflammatory Bowel Disease

Publication Year: 2024 Source: Nutrients PMID: 39519597 DOI: 10.3390/nu16213763

Micronutrient deficiencies are common in inflammatory bowel disease (IBD). The aim of this study was to evaluate micronutrient deficiencies and identify muscular status of patients with IBD. From June 2019 to October 2021, a total of 105 patients with IBD were enrolled prospectively. To obtain objective data, micronutrients were measured …

Fermented Gold Kiwi Improves Gastrointestinal Motility and Functional Constipation: An Animal Study and Human Randomized Clinical Test

Publication Year: 2024 Source: Nutrients PMID: 39519611

No Abstract

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