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A Proteomics Pipeline for Generating Clinical Grade Biomarker Candidates from Data-Independent Acquisition Mass Spectrometry (DIA-MS) Discovery
Publication Year: 2024 Source: Angew Chem Int Ed Engl PMID: 39432331
No Abstract
Kiwifruit Polysaccharides Alleviate Ulcerative Colitis via Regulating Gut Microbiota-Dependent Tryptophan Metabolism and Promoting Colon Fucosylation
Publication Year: 2024 Source: J Agric Food Chem PMID: 39432373
No Abstract
Atopic disease and inflammatory bowel disease: A bidirectional Mendelian randomization study
Publication Year: 2024 Source: Medicine (Baltimore) PMID: 39432625 DOI: 10.1097/MD.0000000000040143
Observational studies have reported associations between atopic diseases, including allergic rhinitis (AR), asthma, atopic dermatitis (AD), and inflammatory bowel disease (IBD), but the causal relationship remains unknown. We utilized pooled data from genome-wide association studies, qualified instrumental variables were screened according to the 3 hypotheses of MR, and bidirectional causality …
Hematopoietic stem cell transplantation therapy for refractory' Crohn disease: A systematic review and meta-analysis
Publication Year: 2024 Source: Medicine (Baltimore) PMID: 39432634
No Abstract
The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells
Publication Year: 2024 Source: Proc Natl Acad Sci U S A PMID: 39432783
No Abstract
A hybrid approach of vision transformers and CNNs for detection of ulcerative colitis
Publication Year: 2024 Source: Sci Rep PMID: 39433818
No Abstract
Next-generation IgA-SEQ allows for high-throughput, anaerobic, and metagenomic assessment of IgA-coated bacteria
Publication Year: 2024 Source: Microbiome PMID: 39434178 DOI: 10.1186/s40168-024-01923-9
BACKGROUND: The intestinal microbiota plays a significant role in maintaining systemic and intestinal homeostasis, but can also influence diseases such as inflammatory bowel disease (IBD) and cancer. Certain bacterial species within the intestinal tract can chronically activate the immune system, leading to low-grade intestinal inflammation. As a result, plasma cells …
Proctitis distal to colorectal anastomosis: a retrospective cohort study of an underreported complication after sigmoidectomy
Publication Year: 2024 Source: Ann Coloproctol PMID: 39434556
No Abstract
The important role of ferroptosis in inflammatory bowel disease
Publication Year: 2024 Source: Front Med (Lausanne) PMID: 39434776 DOI: 10.3389/fmed.2024.1449037
Ferroptosis is a type of regulated cell death that occurs due to the iron-dependent accumulation of lethal reactive oxygen species (ROS) from lipids. Ferroptosis is characterized by distinct morphological, biochemical, and genetic features that differentiate it from other regulated cell death (RCD) types, which include apoptosis, various necrosis types, and …
Establishment of an ulcerative colitis model using colon organoids derived from human induced pluripotent stem cells
Publication Year: 2024 Source: iScience PMID: 39435148 DOI: 10.1016/j.isci.2024.111049
The etiology of inflammatory bowel disease (IBD) is complex, with much room for a greater understanding and development of improved therapies. Therefore, establishing a reliable IBD model is crucial for future advancements. In this study, human induced pluripotent stem (iPS) cell-derived colon organoids (hiPSC-COs) were treated with a combination of …
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