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Unbiased serum metabolomic analysis in cats with naturally occurring chronic enteropathies before and after medical intervention
Publication Year: 2024 Source: Sci Rep PMID: 38521833 DOI: 10.1038/s41598-024-57004-2
Chronic enteropathies (CE) are common disorders in cats and the differentiation between the two main underlying diseases, inflammatory bowel disease (IBD) and low-grade intestinal T-cell lymphoma (LGITL), can be challenging. Characterization of the serum metabolome could provide further information on alterations of disease-associated metabolic pathways and may identify diagnostic or …
Real-World Outcomes of Dual Advanced Therapy in Children and Young Adults with Inflammatory Bowel Disease
Publication Year: 2024 Source: Dig Dis Sci PMID: 38521850 DOI: 10.1007/s10620-024-08379-9
BACKGROUND: Data are limited on the safety and efficacy of combining advanced therapies for refractory patients with IBD. AIM: To evaluate the real-world efficacy and safety of dual advanced therapy (DAT), combining 2 biologics or a biologic with a small molecule, in children and young adults with refractory IBD. METHODS: …
Immunological profile of lactylation-related genes in Crohn's disease: a comprehensive analysis based on bulk and single-cell RNA sequencing data
Publication Year: 2024 Source: J Transl Med PMID: 38521905
No Abstract
Human-derived bacterial strains mitigate colitis via modulating gut microbiota and repairing intestinal barrier function in mice
Publication Year: 2024 Source: BMC Microbiol PMID: 38521930
No Abstract
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease
Publication Year: 2024 Source: J Autoimmun PMID: 38522129 DOI: 10.1016/j.jaut.2024.103181
Inflammatory bowel diseases (IBDs) are chronic intestinal disorders often characterized by a dysregulation of T cells, specifically T helper (Th) 1, 17 and T regulatory (Treg) repertoire. Increasing evidence demonstrates that dietary polyphenols from Mangifera indica L. extract (MIE, commonly known as mango) mitigate intestinal inflammation and splenic Th17/Treg ratio. …
Ultra-Processed Food Consumption and Long-Term Risk of Irritable Bowel Syndrome: A Large-Scale Prospective Cohort Study
Publication Year: 2024 Source: Clin Gastroenterol Hepatol PMID: 38522476
No Abstract
Astragalus polysaccharides ameliorates experimental colitis by regulating memory B cells metabolism
Publication Year: 2024 Source: Chem Biol Interact PMID: 38522565
No Abstract
Letter: Thioguanine, an underutilised option in inflammatory bowel disease?
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38523080
No Abstract
Letter: Modifying the Mayo endoscopic subscore for improved prognostic insights
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38523122 DOI: 10.1111/apt.17912
No Abstract
Letter: Thioguanine, an under-utilised option in inflammatory bowel disease? Authors' reply
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38523135
No Abstract
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