Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Shared Immune Associations Between COVID-19 and Inflammatory Bowel Disease: A Cross-Sectional Observational Study in Shanghai, China
Publication Year: 2024 Source: J Inflamm Res PMID: 38558943 DOI: 10.2147/JIR.S449746
PURPOSE: The rapid global spread of the SARS-CoV-2 Omicron variant introduces a novel complication: the emergence of IBD (inflammatory bowel disease)-like ulcers in certain patients. This research delves into this new challenge by juxtaposing the clinical manifestations and genetic expression patterns of individuals affected by the Omicron variant of COVID-19 …
Enhanced mucosal mitochondrial function corrects dysbiosis and OXPHOS metabolism in IBD
Publication Year: 2024 Source: bioRxiv PMID: 38559035 DOI: 10.1101/2024.03.14.584471
BACKGROUND: Mitochondrial (Mito) dysfunction in IBD reduces mucosal O2 consumption and increases O2 delivery to the microbiome. Increased enteric O2 promotes blooms of facultative anaerobes (eg. Proteobacteria ) and restricts obligate anaerobes (eg. Firmicutes ). Dysbiotic metabolites negatively affect host metabolism and immunity. Our novel compound (AuPhos) upregulates intestinal epithelial …
Smad4 Loss in the Mouse Intestinal Epithelium Alleviates the Pathological Fibrotic Response to Injury in the Colon
Publication Year: 2024 Source: bioRxiv PMID: 38559102 DOI: 10.1101/2024.03.08.578000
Mucosal healing is associated with better clinical outcomes in patients with inflammatory bowel diseases (IBDs). Unresolved injury and inflammation, on the other hand, increases pathological fibrosis and the predisposition to cancer. Loss of Smad4, a tumor suppressor, is known to increase colitis-associated cancer in mouse models of chronic IBD. Since …
Automated Spatial Omics Landscape Analysis Approach Reveals Novel Tissue Architectures in Ulcerative Colitis
Publication Year: 2024 Source: Res Sq PMID: 38559236
No Abstract
Estimating evolutionary and demographic parameters via ARG-derived IBD
Publication Year: 2024 Source: bioRxiv PMID: 38559261 DOI: 10.1101/2024.03.07.583855
Inference of demographic and evolutionary parameters from a sample of genome sequences often proceeds by first inferring identical-by-descent (IBD) genome segments. By exploiting efficient data encoding based on the ancestral recombination graph (ARG), we obtain three major advantages over current approaches: (i) no need to impose a length threshold on …
Perirectal Mucinous Adenocarcinoma After Subtotal-Colectomy for Crohn's Disease: A Case Report
Publication Year: 2024 Source: Cureus PMID: 38559545
No Abstract
Retracted: Application of Health Education Based on Phased Transition Theory Model in Continuous Nursing for Patients with Inflammatory Bowel Disease
Publication Year: 2024 Source: Emerg Med Int PMID: 38298983
No Abstract
Dexamethasone-Loaded Lipid Calcium Phosphate Nanoparticles Treat Experimental Colitis by Regulating Macrophage Polarization in Inflammatory Sites
Publication Year: 2024 Source: Int J Nanomedicine PMID: 38299194
No Abstract
Electroacupuncture Reduces Inflammatory Bowel Disease in Obese Mice by Activating the Nrf2/HO-1 Signaling Pathways and Repairing the Intestinal Barrier
Publication Year: 2024 Source: Diabetes Metab Syndr Obes PMID: 38299195 DOI: 10.2147/DMSO.S449112
BACKGROUND: Electroacupuncture (EA) is used to treat inflammatory bowel disease (IBD). Nevertheless, the precise mechanisms by which this approach safeguards against obesity-induced intestinal barrier damage has not been fully understood. OBJECTIVE: This study aimed to assess whether EA could ameliorate intestinal barrier damage that had been reversed in a mouse …
Tissue markers may predict treatment response to antitumor necrosis factor-α agents in children with Crohn's disease
Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38299301
No Abstract
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide