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Improved diagnosis of faecal incontinence in the gastroenterology domain: The time to act has come
Publication Year: 2024 Source: United European Gastroenterol J PMID: 38329403
No Abstract
Tobacco Smoke Exposure in Early Childhood and Later Risk of Inflammatory Bowel Disease: A Scandinavian Birth Cohort Study
Publication Year: 2024 Source: J Crohns Colitis PMID: 38329478 DOI: 10.1093/ecco-jcc/jjae020
OBJECTIVES: To examine the association between early-life smoking exposure and later risk of inflammatory bowel disease [IBD]. METHODS: We followed 115663 participants from the Norwegian Mother, Father and Child [MoBa] and All Babies in Southeast Sweden [ABIS] cohorts from birth [1997-2009] through 2021. IBD was identified through national patient registers. …
Therapeutic drug monitoring in inflammatory bowel disease: A practical approach
Publication Year: 2024 Source: Indian J Gastroenterol PMID: 38329599 DOI: 10.1007/s12664-024-01527-z
The global burden of inflammatory bowel diseases (IBD) is estimated at 4.9 million and the global prevalence exceeds 0.3%. Multiple newer therapeutic agents have broadened the options for the therapy of IBD in the last three decades. Thiopurines, however, have retained their place as maintenance therapy in IBD, especially in …
Tissue-specific reprogramming leads to angiogenic neutrophil specialization and tumor vascularization in colorectal cancer
Publication Year: 2024 Source: J Clin Invest PMID: 38329810
No Abstract
Lactic acid induces transcriptional repression of macrophage inflammatory response via histone acetylation
Publication Year: 2024 Source: Cell Rep PMID: 38329873
No Abstract
Findings on emergent magnetic resonance imaging in pregnant patients with suspected appendicitis: A single center perspective
Publication Year: 2024 Source: PLoS One PMID: 38329949
No Abstract
Physical Activity and IBD: State of Art and Knowledge, Patients and Healthcare Professionals Points of View, A French Multicenter Cross Sectional Study
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38330214 DOI: 10.1093/ibd/izae009
BACKGROUND: Several studies have reported low levels of physical activity (PA) in patients with inflammatory bowel diseases (IBD), possibly related to a lack of information and support, despite the many recognized benefits such as cardiovascular prevention or quality of life (QoL) improvement. METHODS: The purpose of our study was to …
Thrombocytosis and Transaminitis in Infants Born to Women With Inflammatory Bowel Disease Is Associated With Exposure to Maternal Inflammation In Utero
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38330216 DOI: 10.1093/ibd/izae008
BACKGROUND: Despite reassuring clinical safety data, thrombocytosis, anemia, lymphopenia, and liver function derangements have been observed in infants born to women with inflammatory bowel disease (IBD) treated with thiopurines and biologics. We aimed to define the prevalence, course, associations, and clinical impact of hematological and biochemical abnormalities in such infants. …
Predictors of Complicated Disease Course in Adults and Children With Crohn's Disease: A Nationwide Study from the epi-IIRN
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38330226
No Abstract
Macrophage Tim-3 maintains intestinal homeostasis in DSS-induced colitis by suppressing neutrophil necroptosis
Publication Year: 2024 Source: Redox Biol PMID: 38330550 DOI: 10.1016/j.redox.2024.103072
T-cell immunoglobulin domain and mucin domain-3 (Tim-3) is a versatile immunomodulator that protects against intestinal inflammation. Necroptosis is a type of cell death that regulates intestinal homeostasis and inflammation. The mechanism(s) underlying the protective role of macrophage Tim-3 in intestinal inflammation is unclear; thus, we investigated whether specific Tim-3 knockdown …
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