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Ulcerative colitis and pyoderma gangrenosum refractory to treatment successfully managed with pentoxifylline: a case report

Publication Year: 2024 Source: Ann Med Surg (Lond) PMID: 38333294

No Abstract

Nintedanib-Induced Colitis Can Mimic Inflammatory Bowel Disease

Publication Year: 2024 Source: ACG Case Rep J PMID: 38333722 DOI: 10.14309/crj.0000000000001282

Nintedanib is a medication that has been increasingly used for treatment of idiopathic and progressive pulmonary fibrosis. In this case series, we describe 3 patients with colitis symptoms associated with nintedanib use. Nintedanib discontinuation resulted in symptomatic resolution in all patients. Budesonide decreased symptoms in 1 patient. Clinicians should be …

The alleviative effects comparison of four flavonoids from bamboo leaves on ulcerative colitis in an Alzheimer mouse model

Publication Year: 2024 Source: CNS Neurosci Ther PMID: 38334213

No Abstract

Clinical outcomes and cost savings of a nonmedical switch to a biosimilar in children/young adults with inflammatory bowel disease

Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38334232 DOI: 10.1002/jpn3.12153

OBJECTIVES: The safety, efficacy, and cost savings associated with biosimilar medications are well established. However, a lack of pediatric data exists surrounding clinical outcomes when switching from an originator to a biosimilar. Our primary aim is to evaluate clinical outcomes following a nonmedical switch from the infliximab originator to a …

Small bowel diaphragm disease

Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38334234

No Abstract

Intestinal Colonized Silkworm Chrysalis-Like Probiotic Composites for Multi-Crossed Comprehensive Synergistic Therapy of Inflammatory Bowel Disease

Publication Year: 2024 Source: Small PMID: 38334256 DOI: 10.1002/smll.202310851

Inspired by the timely emergence of silkworm pupae from their cocoons, silkworm chrysalis-like probiotic composites (SCPCs) are developed for the comprehensive therapy of inflammatory bowel disease (IBD), in which probiotics are enveloped as the "pupa" in a sequential layering of silk sericin (SS), tannic acid (TA), and polydopamine, akin to …

Campylobacter jejuni Surface-Bound Protease HtrA, but Not the Secreted Protease nor Protease in Shed Membrane Vesicles, Disrupts Epithelial Cell-to-Cell Junctions

Publication Year: 2024 Source: Cells PMID: 38334616

No Abstract

The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function

Publication Year: 2024 Source: Cells PMID: 38334618 DOI: 10.3390/cells13030227

The transcriptional co-activator lens epithelium-derived growth factor/p75 (LEDGF/p75) plays an important role in the biology of the cell and in several human diseases, including MLL-rearranged acute leukemia, autoimmunity, and HIV-1 infection. In both health and disease, LEDGF/p75 functions as a chromatin tether that interacts with proteins such as MLL1 and …

Current perspectives on fecal microbiota transplantation in inflammatory bowel disease

Publication Year: 2024 Source: Indian J Gastroenterol PMID: 38334893 DOI: 10.1007/s12664-023-01516-8

Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic modality within the domain of inflammatory bowel disease (IBD). While FMT has secured approval and demonstrated efficacy in addressing recurrent and refractory Clostridioides difficile infection, its application in IBD remains an area of active exploration and research. The current status …

Guanosine-Based Multidrug Strategy Delivery for Synergistic Anti-Inflammation

Publication Year: 2024 Source: ACS Macro Lett PMID: 38335274

No Abstract

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