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Adverse Food Reactions in Inflammatory Bowel Disease: State of the Art and Future Perspectives
Publication Year: 2024 Source: Nutrients PMID: 38337636 DOI: 10.3390/nu16030351
Limited knowledge is available about the relationship between food allergies or intolerances and inflammatory bowel disease (IBD). Clinicians frequently encounter patients who report food allergies or intolerances, and gastroenterologists struggle distinguishing between patients with organic disorders and those with functional disorders, which the patients themselves may associate with specific dietary …
Exclusive Enteral Nutrition Beneficially Modulates Gut Microbiome in a Preclinical Model of Crohn's-like Colitis
Publication Year: 2024 Source: Nutrients PMID: 38337648
No Abstract
Intestinal Obstruction as Initial Presentation of Idiopathic Portal and Mesenteric Venous Thrombosis: Diagnosis, Management, and Literature Review
Publication Year: 2024 Source: Diagnostics (Basel) PMID: 38337820
No Abstract
Adalimumab Biosimilar in Pediatric Inflammatory Bowel Disease: A Retrospective Study from the Sicilian Network for Inflammatory Bowel Disease (SN-IBD)
Publication Year: 2024 Source: Healthcare (Basel) PMID: 38338289 DOI: 10.3390/healthcare12030404
BACKGROUND: The utilization of anti-tumor necrosis factor-alpha (anti-TNF-alpha) biosimilars in inflammatory bowel disease (IBD) is constantly increasing. However, pediatric data are limited. This study aimed to assess the effectiveness and safety of adalimumab biosimilar (ADL-BioS) in pediatric IBD patients. METHODS: All consecutive pediatric IBD patients from the Sicilian Network for …
Mucosal Genes Encoding Clock, Inflammation and Their Mutual Regulators Are Disrupted in Pediatric Patients with Active Ulcerative Colitis
Publication Year: 2024 Source: Int J Mol Sci PMID: 38338765 DOI: 10.3390/ijms25031488
Patients with active ulcerative colitis (UC) display a misalignment of the circadian clock, which plays a vital role in various immune functions. Our aim was to characterize the expression of clock and inflammation genes, and their mutual regulatory genes in treatment-naive pediatric patients with UC. Using the Inflammatory Bowel Disease …
Mucin Expression Profiles in Ulcerative Colitis: New Insights on the Histological Mucosal Healing
Publication Year: 2024 Source: Int J Mol Sci PMID: 38339134 DOI: 10.3390/ijms25031858
A structural weakness of the mucus barrier (MB) is thought to be a cause of ulcerative colitis (UC). This study aims to investigate the mucin (MUC) composition of MB in normal mucosa and UC. Ileocolonic biopsies were taken at disease onset and after treatment in 40 patients, including 20 with …
Sterile Fecal Microbiota Transplantation Boosts Anti-Inflammatory T-Cell Response in Ulcerative Colitis Patients
Publication Year: 2024 Source: Int J Mol Sci PMID: 38339169
No Abstract
Prophylactic Intra-abdominal Drainage is Associated With Lower Postoperative Complications in Patients With Crohn's Disease: A Randomized Controlled Trial
Publication Year: 2024 Source: Surg Innov PMID: 38339842
No Abstract
Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis
Publication Year: 2024 Source: Kaohsiung J Med Sci PMID: 38340032 DOI: 10.1002/kjm2.12806
Inflammatory bowel disease (IBD) is a chronic and incurable disorder associated with higher cancer risk and currently faces unsatisfactory treatment outcomes. Ferroptotic cells secrete damage-associated molecular patterns (DAMPs) that recruit and activate immune cells, particularly macrophages. Magnolin has excellent antioxidant and anti-inflammatory properties, but its effect on IBD has not …
Timing and Location of Venous Thromboembolisms After Surgery for Inflammatory Bowel Disease
Publication Year: 2024 Source: J Surg Res PMID: 38340490
No Abstract
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