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Osteonecrosis of the Knee: The Unintended Consequence of Steroid Abuse
Publication Year: 2024 Source: Clin Med Res PMID: 38609146
No Abstract
Polyphenol nanoparticles based on bioresponse for the delivery of anthocyanins
Publication Year: 2024 Source: Food Res Int PMID: 38609214
No Abstract
Three-stage versus modified two-stage surgery for ulcerative colitis: a patient-centred treatment trade-off study
Publication Year: 2024 Source: Colorectal Dis PMID: 38609339
No Abstract
Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis
Publication Year: 2024 Source: Nat Immunol PMID: 38609547
No Abstract
Attenuation of inflammatory bowel disease by oral administration of mucoadhesive polydopamine-coated yeast β-glucan via ROS scavenging and gut microbiota regulation
Publication Year: 2024 Source: J Nanobiotechnology PMID: 38610032 DOI: 10.1186/s12951-024-02434-3
Treatment for inflammatory bowel disease (IBD) is challenging since current anti-inflammatory and immunosuppressive therapies do not address the underlying causes of the illness, which include increased levels of reactive oxygen species (ROS) and dysbiosis of the gut commensal microbiota. Additionally, these treatments often have systemic off-target effects and adverse side …
Different Therapeutic Response to Anti-TNF Drugs in Patients with Axial Spondyloarthritis Depending on Their Clinical Profile: An Unsupervised Cluster Analysis
Publication Year: 2024 Source: J Clin Med PMID: 38610620 DOI: 10.3390/jcm13071855
Background: The objectives were as follows: (a) to identify, among patients with axial spondyloarthritis (axSpA), "clusters" of patients based on the presence of peripheral and extra-musculoskeletal manifestations (EMMs) and (b) to compare the effectiveness of the first anti-TNF drugs across the different clusters after 6 months of follow-up. Methods: An …
Immune-Mediated Inflammatory Diseases Awareness and Management among Physicians Treating Patients with Inflammatory Bowel Disease: An IG-IBD Survey
Publication Year: 2024 Source: J Clin Med PMID: 38610623 DOI: 10.3390/jcm13071857
(1) Background: Inflammatory bowel disease (IBD) is frequently associated to other immune-mediated inflammatory diseases (IMIDs). This study aims at assessing physicians' awareness of the issue and the current status of IMID management. (2) Methods: A web-based survey was distributed to all 567 physicians affiliated to IG-IBD. (3) Results: A total …
Low ALT Is Associated with IBD and Disease Activity: Results from a Nationwide Study
Publication Year: 2024 Source: J Clin Med PMID: 38610634 DOI: 10.3390/jcm13071869
Background: Sarcopenia is underdiagnosed in patients with inflammatory bowel disease (IBD). Low alanine transaminase (ALT) is associated with sarcopenia. We evaluated the association between low ALT and the presence of IBD and disease activity. Methods: Data were collected from a national Israeli health insurer cohort comprising 976,615 patients. Patients with …
Burden of Mental Health among Patients with Inflammatory Bowel Disease-A Cross-Sectional Study from a Tertiary IBD Center in Hungary
Publication Year: 2024 Source: J Clin Med PMID: 38610767 DOI: 10.3390/jcm13072002
Background: Inflammatory bowel diseases (IBDs) are chronic conditions that negatively affect the patient's quality of life. With the spread of the biopsychosocial model, the role of mental health in the activity and course of inflammatory bowel disease is becoming more and more recognized. Our study aimed to assess the prevalence …
The Impact of Phenotype of Inflammatory Bowel Diseases, Inflammation Activity and Therapy on Mucosal Mature Cd83(+) Dendritic Cell
Publication Year: 2024 Source: J Clin Med PMID: 38610835 DOI: 10.3390/jcm13072070
Background: Crohn's disease (CD) and ulcerative colitis (UC) are well-defined phenotypes of chronic inflammatory bowel diseases (IBDs). A mechanism of inflammation in these diseases is partially controlled by the intestinal dendritic cell (DC). In this study, we observed a mature CD83(+) DC in colonic bioptic samples, and its correlation with …
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