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An esophagus cell atlas reveals dynamic rewiring during active eosinophilic esophagitis and remission
Publication Year: 2024 Source: Nat Commun PMID: 38637492
No Abstract
Helminth-derived proteins as immune system regulators: a systematic review of their promise in alleviating colitis
Publication Year: 2024 Source: BMC Immunol PMID: 38637733
No Abstract
Short-chain fatty acid-producing bacterial strains attenuate experimental ulcerative colitis by promoting M2 macrophage polarization via JAK/STAT3/FOXO3 axis inactivation
Publication Year: 2024 Source: J Transl Med PMID: 38637862 DOI: 10.1186/s12967-024-05122-w
BACKGROUND: Patients with inflammatory bowel disease (IBD), dysbiosis, and immunosuppression who receive fecal microbiota transplantation (FMT) from healthy donors are at an increased risk of developing bacteremia. This study investigates the efficacy of a mixture of seven short-chain fatty acid (SCFA)-producing bacterial strains (7-mix), the resulting culture supernatant mixture (mix-sup), …
Refractory Ulcerative Colitis With Associated Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis Syndrome Successfully Treated With Tofacitinib
Publication Year: 2024 Source: ACG Case Rep J PMID: 38638203
No Abstract
Isolated Celiac Artery Vasculitis Presenting as Ileus in a Patient With Ulcerative Colitis
Publication Year: 2024 Source: ACG Case Rep J PMID: 38638204 DOI: 10.14309/crj.0000000000001335
There is a known association between inflammatory bowel disease (IBD) and vasculitis, which can present with mesenteric ischemia or cutaneous manifestations. Infliximab, an anti-tumor necrosis factor (anti-TNF) used to treat IBD, has been implicated as a potential culprit. We present a unique case of a patient with ulcerative colitis who …
Hypoxia, hypoxia-inducible factors and inflammatory bowel diseases
Publication Year: 2024 Source: Gastroenterol Rep (Oxf) PMID: 38638288 DOI: 10.1093/gastro/goae030
Adequate oxygen supply is essential for maintaining the body's normal physiological function. In chronic inflammatory conditions such as inflammatory bowel disease (IBD), insufficient oxygen reaching the intestine triggers the regulatory system in response to environmental changes. However, the pathogenesis of IBD is still under investigation. Recent research has highlighted the …
Development of Ac2-26 Mesoporous Microparticle System as a Potential Therapeutic Agent for Inflammatory Bowel Diseases
Publication Year: 2024 Source: Int J Nanomedicine PMID: 38638365 DOI: 10.2147/IJN.S451589
INTRODUCTION: Inflammatory bowel diseases (IBDs) disrupt the intestinal epithelium, leading to severe chronic inflammation. Current therapies cause adverse effects and are expensive, invasive, and ineffective for most patients. Annexin A1 (AnxA1) is a pivotal endogenous anti-inflammatory and tissue repair protein in IBD. Nanostructured compounds loading AnxA1 or its active N-terminal …
Evaluating the causal association between bronchiectasis and different types of inflammatory bowel disease: a two-sample Mendelian randomization study
Publication Year: 2024 Source: Front Immunol PMID: 38638444 DOI: 10.3389/fimmu.2024.1365108
BACKGROUND AND OBJECTIVES: Previous observational studies have established a connection between bronchiectasis and inflammatory bowel disease (IBD), but none of these studies have provided a clear explanation for the underlying cause of this relationship. The present study thus implemented Mendelian randomization (MR) design to explore possible bidirectional relationships between IBD …
Gingerenone A Attenuates Ulcerative Colitis via Targeting IL-17RA to Inhibit Inflammation and Restore Intestinal Barrier Function
Publication Year: 2024 Source: Adv Sci (Weinh) PMID: 38639442
No Abstract
OASL suppresses infectious bursal disease virus replication by targeting VP2 for degrading through the autophagy pathway
Publication Year: 2024 Source: J Virol PMID: 38639485 DOI: 10.1128/jvi.00181-24
Infectious bursal disease (IBD) is an acute and fatal immunosuppressive disease caused by infectious bursal disease virus (IBDV). As an obligate intracellular parasite, IBDV infection is strictly regulated by host factors. Knowledge on the antiviral activity and possible mechanism of host factors might provide the theoretical basis for the prevention …
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