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Protective Effect of Egg Yolk Lipids against Dextran Sulfate Sodium-Induced Colitis: The Key Role of Gut Microbiota and Short-Chain Fatty Acids
Publication Year: 2024 Source: Mol Nutr Food Res PMID: 38659317
No Abstract
Roles of TRP and PIEZO receptors in autoimmune diseases
Publication Year: 2024 Source: Expert Rev Mol Med PMID: 38659380
No Abstract
Growth differentiation factor-15 serum concentrations reflect disease severity and anemia in patients with inflammatory bowel disease
Publication Year: 2024 Source: World J Gastroenterol PMID: 38659482 DOI: 10.3748/wjg.v30.i13.1899
BACKGROUND: Population of patients with inflammatory bowel disease (IBD) is burdened by various extraintestinal manifestations which substantially contribute to greater morbidity and mortality. Growth-differentiation factor-15 (GDF-15) is often over-expressed under stress conditions, such as inflammation, malignancies, heart failure, myocardial ischemia, and many others. AIM: To explore the association between GDF-15 …
Disease clearance in ulcerative colitis: A new therapeutic target for the future
Publication Year: 2024 Source: World J Gastroenterol PMID: 38659483
No Abstract
Real-world efficacy and safety of tofacitinib treatment in Asian patients with ulcerative colitis
Publication Year: 2024 Source: World J Gastroenterol PMID: 38659488
No Abstract
Discontinuation of therapy in inflammatory bowel disease: Current views
Publication Year: 2024 Source: World J Clin Cases PMID: 38660068 DOI: 10.12998/wjcc.v12.i10.1718
The timely introduction and adjustment of the appropriate drug in accordance with previously well-defined treatment goals is the foundation of the approach in the treatment of inflammatory bowel disease (IBD). The therapeutic approach is still evolving in terms of the mechanism of action but also in terms of the possibility …
Macrophage polarization: an important role in inflammatory diseases
Publication Year: 2024 Source: Front Immunol PMID: 38660308 DOI: 10.3389/fimmu.2024.1352946
Macrophages are crucial cells in the human body's innate immunity and are engaged in a variety of non-inflammatory reactions. Macrophages can develop into two kinds when stimulated by distinct internal environments: pro-inflammatory M1-like macrophages and anti-inflammatory M2-type macrophages. During inflammation, the two kinds of macrophages are activated alternatively, and maintaining …
Potential shared pathogenic mechanisms between endometriosis and inflammatory bowel disease indicate a strong initial effect of immune factors
Publication Year: 2024 Source: Front Immunol PMID: 38660311 DOI: 10.3389/fimmu.2024.1339647
INTRODUCTION: Over the past decades, immune dysregulation has been consistently demonstrated being common charactoristics of endometriosis (EM) and Inflammatory Bowel Disease (IBD) in numerous studies. However, the underlying pathological mechanisms remain unknown. In this study, bioinformatics techniques were used to screen large-scale gene expression data for plausible correlations at the …
De Novo Crohn's Disease Diagnosed in the Setting of Acute SARS-Cov-2 Infection Requiring Escalation of Infliximab Therapy Guided by Personalized Pharmacokinetics
Publication Year: 2024 Source: J Pediatr Perinatol Child Health PMID: 38660332 DOI: 10.26502/jppch.74050172
Here, we describe a 7-year-old girl who was diagnosed with an early-onset Crohn's disease in the setting of COVID-19 illness. Her disease process responded poorly to standard infliximab dosing, necessitating repeat hospitalizations and red blood cell transfusions. Remission was subsequently induced using a personalized infliximab pharmacokinetic profile based on therapeutic …
Racial and Ethnic Disparities in Health-Related Outcomes in Crohn's Disease: Results From the National Health and Wellness Survey
Publication Year: 2024 Source: Crohns Colitis 360 PMID: 38660453
No Abstract
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