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Clinical and imaging findings in enteropathic spondyloarthritis with special emphasize in diagnostic delay: a cross-sectional study
Publication Year: 2024 Source: Ther Adv Chronic Dis PMID: 38380226 DOI: 10.1177/20406223241229843
BACKGROUND: Enteropathic spondyloarthritides (eSpAs) are chronic inflammatory joint diseases associated with inflammatory bowel disease (IBD). Limited data are available on the prevalence since arthritis in IBD patients may be underestimated because medications may hide disease activity with a possible diagnostic delay. OBJECTIVES: We aimed to evaluate diagnostic delay in eSpA …
Dissecting the genetic architecture of quantitative traits using genome-wide identity-by-descent sharing
Publication Year: 2024 Source: Mol Ecol PMID: 38380534 DOI: 10.1111/mec.17299
Additive and dominance genetic variances underlying the expression of quantitative traits are important quantities for predicting short-term responses to selection, but they are notoriously challenging to estimate in most non-model wild populations. Specifically, large-sized or panmictic populations may be characterized by low variance in genetic relatedness among individuals which, in …
Fufangxiaopi formula alleviates DSS-induced colitis in mice by inhibiting inflammatory reaction, protecting intestinal barrier and regulating intestinal microecology
Publication Year: 2024 Source: J Ethnopharmacol PMID: 38380568
ETHNOPHARMACOLOGICAL RELEVANCE: Fufangxiaopi Formula (FF) is a modified form of Sishen Wan, traditionally used for treating diarrhea. The application of FF for treating ulcerative colitis (UC) has achieved desirable outcomes in clinical settings. However, the underlying mechanism of the effect of FF on UC is yet to be determined. AIM …
Therapeutic drug monitoring of vedolizumab therapy in inflammatory bowel disease
Publication Year: 2024 Source: J Gastroenterol Hepatol PMID: 38380724
No Abstract
Low-FODMAP diet and hidradenitis suppurativa: the role of nutritionists in the management of dermato-endocrine disorders
Publication Year: 2024 Source: Minerva Endocrinol (Torino) PMID: 38381473
No Abstract
A tailored series of engineered yeasts for the cell-dependent treatment of inflammatory bowel disease by rational butyrate supplementation
Publication Year: 2024 Source: Gut Microbes PMID: 38381494 DOI: 10.1080/19490976.2024.2316575
Intestinal microbiota dysbiosis and metabolic disruption are considered essential characteristics in inflammatory bowel disorders (IBD). Reasonable butyrate supplementation can help patients regulate intestinal flora structure and promote mucosal repair. Here, to restore microbiota homeostasis and butyrate levels in the patient's intestines, we modified the genome of Saccharomyces cerevisiae to produce …
UCFNNet: Ulcerative colitis evaluation based on fine-grained lesion learner and noise suppression gating
Publication Year: 2024 Source: Comput Methods Programs Biomed PMID: 38382306
No Abstract
Prediction of response to anti-TNFα using integrative computational approaches in Crohn's disease-Needle in a haystack or a promising biomarker?
Publication Year: 2024 Source: Cell Rep Med PMID: 38382470
No Abstract
Clinical factors associated with severity in patients with inflammatory bowel disease in Brazil based on 2-year national registry data from GEDIIB
Publication Year: 2024 Source: Sci Rep PMID: 38383742 DOI: 10.1038/s41598-024-54332-1
The Brazilian Organization for Crohn's Disease and Colitis (GEDIIB) established a national registry of inflammatory bowel disease (IBD). The aim of the study was to identify clinical factors associated with disease severity in IBD patients in Brazil. A population-based risk model aimed at stratifying the severity of IBD based on …
IL-10 constrains sphingolipid metabolism to limit inflammation
Publication Year: 2024 Source: Nature PMID: 38383790
No Abstract
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