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Bowel preparation for elective colectomy in Crohn's disease: results from a global cohort study using the NSQIP database
Publication Year: 2024 Source: Colorectal Dis PMID: 38385895
No Abstract
Two New Drugs for Ulcerative Colitis
Publication Year: 2024 Source: Am J Nurs PMID: 38386827
No Abstract
mRNA-1273 vaccinated inflammatory bowel disease patients receiving TNF inhibitors develop broad and robust SARS-CoV-2-specific CD8(+) T cell responses
Publication Year: 2024 Source: J Autoimmun PMID: 38387105 DOI: 10.1016/j.jaut.2024.103175
SARS-CoV-2-specific CD8(+) T cells recognize conserved viral peptides and in the absence of cross-reactive antibodies form an important line of protection against emerging viral variants as they ameliorate disease severity. SARS-CoV-2 mRNA vaccines induce robust spike-specific antibody and T cell responses in healthy individuals, but their effectiveness in patients with …
Gut microbiota-based discovery of Houttuyniae Herba as a novel prebiotic of Bacteroides thetaiotaomicron with anti-colitis activity
Publication Year: 2024 Source: Biomed Pharmacother PMID: 38387133
No Abstract
Response to "De Novo Crohn's Disease in Children With Ulcerative Colitis Undergoing Ileal Pouch Anal Anastomosis: A Multicenter, Retrospective Study From the Pediatric IBD Porto Group of the ESPGHAN"
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38387614 DOI: 10.1093/ibd/izae021
No Abstract
Impact of immunosuppressive therapy on SARS-CoV-2 mRNA vaccine effectiveness in patients with immune-mediated inflammatory diseases: a Danish nationwide cohort study
Publication Year: 2024 Source: BMJ Open PMID: 38387988 DOI: 10.1136/bmjopen-2023-077408
OBJECTIVE: Patients receiving immunosuppressives have been excluded from trials for SARS-CoV-2 vaccine efficacy. Investigation of immunosuppressants' impact on effectiveness of vaccines, particularly in patients with immune-mediated inflammatory diseases (IMID), is therefore required. DESIGN: We performed a nationwide cohort study to assess the risk of COVID-19 infection in vaccinated patients with …
Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL
Publication Year: 2024 Source: RMD Open PMID: 38388171
No Abstract
The gut ileal mucosal virome is disturbed in patients with Crohn's disease and exacerbates intestinal inflammation in mice
Publication Year: 2024 Source: Nat Commun PMID: 38388538 DOI: 10.1038/s41467-024-45794-y
Gut bacteriome dysbiosis is known to be implicated in the pathogenesis of inflammatory bowel disease (IBD). Crohn's disease (CD) is an IBD subtype with extensive mucosal inflammation, yet the mucosal virome, an empirical modulator of the bacteriome and mucosal immunity, remains largely unclear regarding its composition and role. Here, we …
Porphyromonas gingivalis aggravates colitis via a gut microbiota-linoleic acid metabolism-Th17/Treg cell balance axis
Publication Year: 2024 Source: Nat Commun PMID: 38388542 DOI: 10.1038/s41467-024-45473-y
Periodontitis is closely related to inflammatory bowel disease (IBD). An excessive and non-self-limiting immune response to the dysbiotic microbiome characterizes the two. However, the underlying mechanisms that overlap still need to be clarified. We demonstrate that the critical periodontal pathogen Porphyromonas gingivalis (Pg) aggravates intestinal inflammation and Th17/Treg cell imbalance …
Ultra-processed foods and food additives in gut health and disease
Publication Year: 2024 Source: Nat Rev Gastroenterol Hepatol PMID: 38388570
No Abstract
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