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Dopamine Polymerization-Mediated Surface Functionalization toward Advanced Bacterial Therapeutics
Publication Year: 2024 Source: Acc Chem Res PMID: 38422996
No Abstract
Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota
Publication Year: 2024 Source: Cell Host Microbe PMID: 38423015 DOI: 10.1016/j.chom.2024.02.003
Reversible genomic DNA inversions control the expression of numerous gut bacterial molecules, but how this impacts disease remains uncertain. By analyzing metagenomic samples from inflammatory bowel disease (IBD) cohorts, we identified multiple invertible regions where a particular orientation correlated with disease. These include the promoter of polysaccharide A (PSA) of …
Fatty Acid Oxidation Promotes Apoptotic Resistance and Proinflammatory Phenotype of CD4(+) Tissue-resident Memory T cells in Crohn's Disease
Publication Year: 2024 Source: Cell Mol Gastroenterol Hepatol PMID: 38423357
No Abstract
Banxia Xiexin decoction modulates gut microbiota and gut microbiota metabolism to alleviate DSS-induced ulcerative colitis
Publication Year: 2024 Source: J Ethnopharmacol PMID: 38423412
No Abstract
Chronic vulvar aphthous ulcer in Crohn's disease
Publication Year: 2024 Source: Am J Obstet Gynecol PMID: 38423448
No Abstract
Reconstruct recent multi-population migration history by using identical-by-descent sharing
Publication Year: 2024 Source: J Genet Genomics PMID: 38423503 DOI: 10.1016/j.jgg.2024.02.006
Identical-by-descent (IBD) is a fundamental genomic characteristic in population genetics and has been widely used for population history reconstruction. However, limited by the nature of IBD, which could only capture the relationship between two individuals/haplotypes, existing IBD-based history inference is constrained to two populations. In this study, we propose a …
Infliximab rescue therapy in a case of severe granulomatous colitis associated with rituximab use
Publication Year: 2024 Source: BMJ Case Rep PMID: 38423571
No Abstract
Pyoderma Gangrenosum: Diagnostic Criteria, Subtypes, Systemic Associations, and Workup
Publication Year: 2024 Source: Dermatol Clin PMID: 38423678
Pyoderma gangrenosum (PG) is an inflammatory neutrophilic dermatosis with variable clinical features. The classic presentation is an ulceration with an erythematous to violaceous undermined border. Extracutaneous manifestations may occur. Associated systemic diseases include inflammatory bowel disease, inflammatory arthritides, and hematologic disorders. The pathophysiologic mechanism of disease is not completely known …
Treatment of Pyoderma Gangrenosum
Publication Year: 2024 Source: Dermatol Clin PMID: 38423680
Pyoderma gangrenosum is a rare neutrophilic dermatosis that results in painful cutaneous ulcers and is frequently associated with underlying hematologic disorders, inflammatory bowel disease, or other autoimmune disorders. Pathogenesis involves an imbalance between proinflammatory and anti-inflammatory mediators, leading to tissue damage from neutrophils. First-line treatment options with the greatest evidence …
Palisaded Neutrophilic Granulomatous Dermatitis, Bowel-Associated Dermatosis-Arthritis Syndrome, and Rheumatoid Neutrophilic Dermatitis
Publication Year: 2024 Source: Dermatol Clin PMID: 38423688
Neutrophilic dermatosis is a heterogeneous group of inflammatory skin diseases characterized by the presence of a sterile neutrophilic infiltrate on histopathology. Three specific types of neutrophilic dermatoses are reviewed in this article: palisaded neutrophilic granulomatous dermatitis, bowel-associated dermatosis-arthritis syndrome, and rheumatoid neutrophilic dermatitis. The authors review the literature and highlight …
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