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New functions and roles of the Na(+)-H(+)-exchanger NHE3
Publication Year: 2024 Source: Pflugers Arch PMID: 38448727
No Abstract
Diet-derived circulating antioxidants and risk of inflammatory bowel disease: a Mendelian randomization study and meta-analysis
Publication Year: 2024 Source: Front Immunol PMID: 38449867 DOI: 10.3389/fimmu.2024.1334395
BACKGROUND: Previous studies have shown conflicting results regarding the impact of circulating antioxidants on the risk of inflammatory bowel disease (IBD). In this study, our intent was to investigate the causal relationship between circulating antioxidants and IBD using Mendelian randomization (MR). METHODS: Instrumental variables for absolute circulating antioxidants (ascorbate, retinol, …
[Trends in the characteristics of patients treated with nutritional supplements in the Northern Area of Gran Canaria in the period 2016 -2021]
Publication Year: 2024 Source: Nutr Hosp PMID: 38450493 DOI: 10.20960/nh.04940
Aim: to assess the prescription of oral nutritional supplements (ONS) in the Northern Area of Gran Canaria in the period 2016-2021. Materials and methods: based on electronic prescription data, the first ONS prescription during 2016-2021 was analyzed considering age, gender, nutritional requirements (NR), body mass index (BMI), percentage of weight …
Update for surgeons on novel induction treatments for acute severe inflammatory bowel disease associated colitis
Publication Year: 2024 Source: ANZ J Surg PMID: 38450582 DOI: 10.1111/ans.18924
BACKGROUND: The landscape of biologic agents for the treatment of inflammatory bowel disease (IBD) associated colitis is rapidly evolving, requiring surgeons to be up-to-date as part of multi-disciplinary, evidence-based care. An update on novel therapies used to induce remission in IBD-associated colitis is presented. METHODS: A systematic search through Ovid …
Potential effects of nutrition-induced alteration of gut microbiota on inflammatory bowel disease: A review
Publication Year: 2024 Source: J Dig Dis PMID: 38450936 DOI: 10.1111/1751-2980.13256
Inflammatory bowel disease (IBD), mainly comprising ulcerative colitis and Crohn's disease, is a group of gradually progressive diseases bringing significant mental anguish and imposes serious economic burdens. Interplay of genetic, environmental, and immunological factors have been implicated in its pathogenesis. Nutrients, as crucial environmental determinants, mainly encompassing carbohydrates, fats, proteins, …
Identification of key biomarkers for predicting CAD progression in inflammatory bowel disease via machine-learning and bioinformatics strategies
Publication Year: 2024 Source: J Cell Mol Med PMID: 38451044 DOI: 10.1111/jcmm.18175
The study aimed to identify the biomarkers for predicting coronary atherosclerotic lesions progression in patients with inflammatory bowel disease (IBD). Related transcriptome datasets were seized from Gene Expression Omnibus database. IBD-related modules were identified via Weighted Gene Co-expression Network Analysis. The 'Limma' was applied to screen differentially expressed genes between …
Surgical outcomes of very-early-onset ulcerative colitis: retrospective comparative study with older pediatric patients
Publication Year: 2024 Source: Pediatr Surg Int PMID: 38451357
No Abstract
Redo IPAA for long rectal cuff syndrome after ileoanal pouch for inflammatory bowel disease
Publication Year: 2024 Source: Tech Coloproctol PMID: 38451358 DOI: 10.1007/s10151-023-02909-9
ABTRACT: BACKGROUND: When constructing an ileal pouch-anal anastomosis (IPAA), the rectal cuff should ideally be 1-2 cm long to avoid subsequent complications. METHODS: We identified patients from our IBD center who underwent redo IPAA for a long rectal cuff. Long rectal cuff syndrome (LRCS) was defined as a symptomatic rectal …
Safety of Secukinumab from 1 Million Patient-Years of Exposure: Experience from Post-Marketing Setting and Clinical Trials
Publication Year: 2024 Source: Dermatol Ther (Heidelb) PMID: 38451423 DOI: 10.1007/s13555-024-01122-2
INTRODUCTION: Secukinumab is an anti-interleukin (IL)-17A monoclonal antibody indicated for multiple immunological disorders. Here, we aim to summarize secukinumab safety in clinical trials (CTs) and post-marketing setting (PMS) until 25 June 2022. METHODS: Adverse events (AEs) were summarized with crude reporting rate (RR) per 100 patient-years (PY) in PMS for …
Interferon Regulatory Factor 5 Gene Polymorphisms and mRNA Expression Levels Are Associated with Neuromyelitis Optica Spectrum Disorder
Publication Year: 2024 Source: Mol Neurobiol PMID: 38451436
No Abstract
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