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Gut microbiota-based discriminative model for patients with ulcerative colitis: A meta-analysis and real-world study
Publication Year: 2024 Source: Medicine (Baltimore) PMID: 38457570
No Abstract
Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation
Publication Year: 2024 Source: Lancet PMID: 38458222 DOI: 10.1016/S0140-6736(24)00052-7
Inflammatory bowel disease (IBD) affects reproductive planning due to psychological effects and mechanical problems related to surgery. Children of people with IBD have an increased risk of about 10% if one parent has IBD and up to 33% if both parents have IBD. The fertility of people with IBD is …
Chemopreventive and immunomodulatory effects of phenolic-rich extract of Commiphora leptophloeos against inflammatory bowel disease: Preclinical evidence
Publication Year: 2024 Source: J Ethnopharmacol PMID: 38458342 DOI: 10.1016/j.jep.2024.118025
ETHNOPHARMACOLOGY RELEVANCE: Commiphora leptophloeos (Mart.) J.B. Gillet (Burseraceae) is a medicinal plant native to Brazil, popularly known as "imburana". Homemade leaf decoction and maceration were used to treat general inflammatory problems in the Brazilian Northeast population. Our previous research confirmed the anti-inflammatory activity of the C. leptophloeos hydroalcoholic leaf extract. …
Gut Immunomodulation with Vedolizumab prior to Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients with Inflammatory Bowel Disease
Publication Year: 2024 Source: Transplant Cell Ther PMID: 38458476 DOI: 10.1016/j.jtct.2024.03.006
Inborn errors of immunity (IEI) are often associated with inflammatory bowel disease (IBD). IEI can be corrected by allogeneic hematopoietic stem cell transplantation (HSCT); however, peritransplantation intestinal inflammation may increase the risk of gut graft-versus-host disease (GVHD). Vedolizumab inhibits the homing of lymphocytes to the intestine and may attenuate gut …
Clinical outcomes of patients with remitting ulcerative colitis after discontinuation of indigo naturalis
Publication Year: 2024 Source: Sci Rep PMID: 38459203
No Abstract
Algorithmic Identification of Treatment-Emergent Adverse Events From Clinical Notes Using Large Language Models: A Pilot Study in Inflammatory Bowel Disease
Publication Year: 2024 Source: Clin Pharmacol Ther PMID: 38459719 DOI: 10.1002/cpt.3226
Outpatient clinical notes are a rich source of information regarding drug safety. However, data in these notes are currently underutilized for pharmacovigilance due to methodological limitations in text mining. Large language models (LLMs) like Bidirectional Encoder Representations from Transformers (BERT) have shown progress in a range of natural language processing …
Epstein-Barr virus associated colitis in kidney transplant patients: a case series
Publication Year: 2024 Source: Infect Dis (Lond) PMID: 38459811 DOI: 10.1080/23744235.2024.2326594
BACKGROUND: Gastrointestinal complications are common in kidney transplant (KT) patients and can be a consequence of the chronic use of immunosuppression. The differential diagnosis of colitis in KT patients includes intolerance to immunosuppressive agents, namely mycophenolate mofetil, de novo inflammatory bowel disease (IBD) and opportunistic infections. Epstein-Barr virus (EBV) infection …
Two-Year Efficacy and Safety of Mirikizumab Following 104 Weeks of Continuous Treatment for Ulcerative Colitis: Results From the LUCENT-3 Open-Label Extension Study
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38459910
No Abstract
Beyond Discrimination: A Call for Comprehensive Assessment of Clinical Prediction Models in Inflammatory Bowel Disease
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38460148
No Abstract
Celiac Disease-Related Conditions: Who to Test?
Publication Year: 2024 Source: Gastroenterology PMID: 38460606 DOI: 10.1053/j.gastro.2024.02.044
Celiac disease (CeD) is a chronic immune-mediated condition triggered by gluten consumption in genetically predisposed individuals. Approximately 1% of the general population is affected by the disorder. Disease presentation is heterogeneous and, despite growing awareness among physicians and the public, it continues to be underestimated. The most effective strategy for …
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