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IBDTransDB: a manually curated transcriptomic database for inflammatory bowel disease
Publication Year: 2024 Source: Database (Oxford) PMID: 38564306 DOI: 10.1093/database/baae026
Inflammatory Bowel Disease (IBD) therapies are ineffective in at least 40% patients, and transcriptomic datasets have been widely used to reveal the pathogenesis and to identify the novel drug targets for these patients. Although public IBD transcriptomic datasets are available from many web-based tools/databases, due to the unstructured metadata and …
Symptom management experiences of Chinese individuals with Crohn's disease: A longitudinal descriptive qualitative study
Publication Year: 2024 Source: Res Nurs Health PMID: 38564311
No Abstract
Confocal laser endomicroscopy as predictive biomarker of clinical and endoscopic efficacy of vedolizumab in ulcerative colitis: The DETECT study
Publication Year: 2024 Source: PLoS One PMID: 38564601
No Abstract
Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells
Publication Year: 2024 Source: J Ethnopharmacol PMID: 38565408 DOI: 10.1016/j.jep.2024.118131
ETHNOPHARMACOLOGICAL RELEVANCE: Sarcandra glabra is officially named Zhong Jie Feng as a traditional medicine. In the nationality of Yao and Zhuang, it has been used to treat digestive diseases like stomachache and dysentery. Similarly, in Dai nationality, it has been used to treat intestinal diseases like gastric ulcers. However, the …
Advancements of Macrophages Involvement in Pathological Progression of Colitis-Associated Colorectal Cancer and Associated Pharmacological Interventions
Publication Year: 2024 Source: Chin J Integr Med PMID: 38565799
No Abstract
A novel neuroimmune modulation system for the treatment of rheumatoid arthritis
Publication Year: 2024 Source: Bioelectron Med PMID: 38566215
No Abstract
Morphological and regional spontaneous functional aberrations in the brain associated with Crohn's disease: a systematic review and coordinate-based meta-analyses
Publication Year: 2024 Source: Cereb Cortex PMID: 38566507
No Abstract
Role of Calprotectin, IL-6, and CRP in Distinguishing Between Inflammatory Bowel Disease and Diarrhea Predominant Irritable Bowel Syndrome
Publication Year: 2024 Source: Med Arch PMID: 38566874 DOI: 10.5455/medarh.2024.78.105-111
BACKGROUND: The early establishment of prophylaxis and immediate administration of anticoagulant therapy upon the diagnosis of venous thromboembolism should be the treatment objectives in these patients. OBJECTIVE: The study aimed to determine the optimal cut-off point of Calprotectin, IL-6 (interleukin-6), CRP (C reactive protein) to differentiate UC, IBS-D. METHODS: A …
An updated advancement of bifunctional IL-27 in inflammatory autoimmune diseases
Publication Year: 2024 Source: Front Immunol PMID: 38566992
No Abstract
Activation of angiogenin expression in macrophages by lipopolysaccharide via the TLR4/NF-κB pathway in colitis
Publication Year: 2024 Source: Acta Biochim Biophys Sin (Shanghai) PMID: 38567413 DOI: 10.3724/abbs.2024013
Inflammatory bowel disease (IBD) is a debilitating condition that can lead to life-threatening complications. Macrophages are crucial in IBD management because they secrete various cytokines and regulate tissue repair. Macrophage-derived angiogenin (ANG) has been shown to be essential for limiting colonic inflammation, but its upstream regulatory pathway and role in …
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