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Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling
Publication Year: 2024 Source: Sci Adv PMID: 38569041 DOI: 10.1126/sciadv.adj7666
Inflammation-associated fibroblasts (IAFs) are associated with progression and drug resistance of chronic inflammatory diseases such as inflammatory bowel disease (IBD), but their direct impact on epithelial cells is unknown. Here, we developed an in vitro model whereby human colon fibroblasts are induced by specific cytokines and recapitulate key features of …
Confirmatory validation of the patient health questionnaire - 4 (PHQ-4) for gastrointestinal disorders: A large-scale cross-sectional survey
Publication Year: 2024 Source: J Psychosom Res PMID: 38569449 DOI: 10.1016/j.jpsychores.2024.111654
OBJECTIVE: Using the large Rome Foundation Global Epidemiology Survey dataset, the aim of this study was to evaluate the construct and convergent validity and internal consistency of the PHQ-4 across both gastrointestinal and non-gastrointestinal condition cohorts. Another aim was to provide descriptive information about the PHQ-4 including means, confidence intervals …
Our extended microbiome: The human-relevant metabolites and biology of fermented foods
Publication Year: 2024 Source: Cell Metab PMID: 38569469
No Abstract
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling
Publication Year: 2024 Source: Cell PMID: 38569542
No Abstract
Parenteral n-3 polyunsaturated fatty acids supplementation improves postoperative recovery for patients with Crohn's disease after bowel resection: a randomized, unblinded controlled clinical trial
Publication Year: 2024 Source: Am J Clin Nutr PMID: 38569774
No Abstract
Utilizing the gut microbiome as a biomarker of response to dietary interventions in inflammatory bowel disease: moving toward precision nutrition
Publication Year: 2024 Source: Am J Clin Nutr PMID: 38569783 DOI: 10.1016/j.ajcnut.2024.01.022
No Abstract
Gut metabolome and microbiota signatures predict response to treatment with exclusive enteral nutrition in a prospective study in children with active Crohn's disease
Publication Year: 2024 Source: Am J Clin Nutr PMID: 38569785
No Abstract
Gut microbial metabolism of 5-aminosalicylic acid in inflammatory bowel disease
Publication Year: 2024 Source: Gut PMID: 38569847
No Abstract
Influential factors on disease activity in Crohn's disease and their Roc curve evaluation: a cross-sectional study
Publication Year: 2024 Source: BMC Gastroenterol PMID: 38570741
No Abstract
Dental management of people with complex or rare inherited bleeding disorders
Publication Year: 2024 Source: Haemophilia PMID: 38571337 DOI: 10.1111/hae.15005
Advances in haematological therapies for people with complex or rare inherited bleeding disorders (IBD) have resulted in them living longer, retaining their natural teeth with greater expectations of function and aesthetics. Dental management strategies need to evolve to meet these challenges. Utilising low level laser diode therapy to reduce pre-operative …
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