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Protocol for isolating single species of bacteria with swarming ability from human feces

Publication Year: 2024 Source: STAR Protoc PMID: 38573864

No Abstract

Self-assembling peptide hydrogel scaffold integrating stem cell-derived exosomes for infected bone defects

Publication Year: 2024 Source: J Biomater Sci Polym Ed PMID: 38574263 DOI: 10.1080/09205063.2024.2336316

Infected bone defect (IBD) is a great challenge in orthopedics, which involves in bone loss and infection. Here, a self-assembling hydrogel scaffold (named AMP-RAD/EXO), integrating antimicrobial peptides(AMPs), RADA16 and BMSCs exosomes with an innovative strategy, is developed and applied in IBD treatment for sustained antimicrobial ability, accelerating osteoblasts proliferation and …

Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant responses and microbiota modification

Publication Year: 2024 Source: Biomed Pharmacother PMID: 38574618 DOI: 10.1016/j.biopha.2024.116514

Plant-derived nanovesicles (PDNVs) have recently emerged as natural delivery systems of biofunctional compounds toward mammalian cells. Considering their already described composition, anti-inflammatory properties, stability, and low toxicity, PDNVs offer a promising path for developing new preventive strategies for several inflammatory diseases, among which the inflammatory bowel disease (IBD). In this …

Mitigation of inflammatory bowel disease-related osteoporosis by oxyberberine: Insights into the RANKL/NF-κB signaling pathway

Publication Year: 2024 Source: Biomed Pharmacother PMID: 38574627

No Abstract

TL1A inhibition for inflammatory bowel disease treatment: From inflammation to fibrosis

Publication Year: 2024 Source: Med PMID: 38574740 DOI: 10.1016/j.medj.2024.03.010

The pivotal role of TL1A in modulating immune pathways crucial for inflammatory bowel disease (IBD) and intestinal fibrosis offers a promising therapeutic target. Phase 2 trials (TUSCANY and ARTEMIS-UC) evaluating an anti-TL1A antibody show progress in expanding IBD therapeutic options. First-in-human data reveal reduced expression of genes associated with extracellular …

Cmtm4 deficiency exacerbates colitis by inducing gut dysbiosis and S100a8/9 expression

Publication Year: 2024 Source: J Genet Genomics PMID: 38575111

No Abstract

Associations of Eosinophilic Gastrointestinal Disorders with Other Gastrointestinal and Allergic Diseases

Publication Year: 2024 Source: Immunol Allergy Clin North Am PMID: 38575227

No Abstract

Is the writing on the wall? The relationship between the number of disease-modifying anti-inflammatory bowel disease drugs used and the risk of surgical resection

Publication Year: 2024 Source: J Gastrointest Surg PMID: 38575464

No Abstract

Identification and surgical management of acute severe ulcerative colitis: A guide for general practitioners

Publication Year: 2024 Source: Aust J Gen Pract PMID: 38575541

No Abstract

Developmental self-reactivity determines pathogenic Tc17 differentiation potential of naive CD8(+) T cells in murine models of inflammation

Publication Year: 2024 Source: Nat Commun PMID: 38575593

No Abstract

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