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Flavokawain B inhibits NF-κB inflammatory signaling pathway activation in inflammatory bowel disease by targeting TLR2
Publication Year: 2024 Source: Toxicol Appl Pharmacol PMID: 38583725 DOI: 10.1016/j.taap.2024.116922
Inflammatory bowel disease (IBD) is characterized by recurrent inflammatory reactions in the intestinal mucosa, including ulcerative colitis (UC) and Crohn's disease (CD). The expression of Toll-like receptor 2 (TLR2) has been observed to increase during the progression of IBD. Flavokawain B (FKB), a natural chalcone with potent anti-inflammatory activity, exerts …
Cost variation of nonelective surgery for ulcerative colitis across the United States
Publication Year: 2024 Source: J Gastrointest Surg PMID: 38583900
No Abstract
Evolution of laparoscopic ileal pouch-anal anastomosis: impact of enhanced recovery program, medication changes, and staged approaches on outcomes
Publication Year: 2024 Source: J Gastrointest Surg PMID: 38583902
No Abstract
Immunomodulation by juglone alleviates acute graft-versus-host disease without compromising the graft-versus-leukaemia activity in mice
Publication Year: 2024 Source: Br J Pharmacol PMID: 38584000
No Abstract
Preventing and managing cardiovascular events in patients with inflammatory bowel diseases treated with small-molecule drugs, an international Delphi consensus
Publication Year: 2024 Source: Dig Liver Dis PMID: 38584033 DOI: 10.1016/j.dld.2024.03.010
Janus kinase (JAK) inhibitors and sphingosine 1 phosphate (S1P) receptor modulators are small molecule drugs (SMDs) approved for IBD treatment. Their use in clinical practice might be limited due to cardiovascular concerns. We aimed to provide guidance on risk assessment, monitoring, and management strategies, aiming to minimize potential cardiovascular risks …
Chronic Kidney Disease in Inflammatory Bowel Disease: a Systematic Review and Meta-analysis
Publication Year: 2024 Source: J Crohns Colitis PMID: 38584452 DOI: 10.1093/ecco-jcc/jjae049
Inflammatory bowel disease [IBD] is associated with various immune-mediated disorders including spondylarthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and uveitis. Chronic kidney disease [CKD] is defined by a reduction in kidney function (estimated glomerular filtration rate [eGFR] less than 60 ml/min/1.73m2] and/or damage markers that are present for at least 3 …
The Development of Serrated Epithelial Change in Ulcerative Colitis is not Significantly Associated With Increased Histologic Inflammation
Publication Year: 2024 Source: Am J Surg Pathol PMID: 38584461
No Abstract
Usage Behaviour and Adoption Criteria for Mobile Health Solutions in Patients with Chronic Diseases in Gastroenterology
Publication Year: 2024 Source: Visc Med PMID: 38584857
No Abstract
Clinical Presentation and Outcome of Critically Ill Patients with Inflammatory Bowel Disease
Publication Year: 2024 Source: Visc Med PMID: 38584860 DOI: 10.1159/000537885
INTRODUCTION: Admission to the intensive care unit severely affects inflammatory bowel disease (IBD) patients. This study aimed to determine factors associated with mortality in IBD patients admitted to the intensive care unit. METHODS: A retrospective cohort study was performed, analyzing data of all IBD patients admitted to the Department of …
Microbiota Therapy in Inflammatory Bowel Disease
Publication Year: 2024 Source: Visc Med PMID: 38584861 DOI: 10.1159/000536254
BACKGROUND: In both Crohn's disease (CD) and ulcerative colitis (UC), the two major forms of inflammatory bowel disease (IBD) the immune reaction is - at least partially - directed against components of the luminal microbiota of the gut. These immune responses as well as other factors contribute to a phenomenon …
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