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QingChang-XiaoPi decoction ameliorates intestinal inflammation of ulcerative colitis by regulating the pathogenicity of Th17 cells
Publication Year: 2024 Source: Phytomedicine PMID: 38876011
No Abstract
Gastrointestinal Biofilms: Endoscopic Detection, Disease Relevance, and Therapeutic Strategies
Publication Year: 2024 Source: Gastroenterology PMID: 38876174 DOI: 10.1053/j.gastro.2024.04.032
Gastrointestinal biofilms are matrix-enclosed, highly heterogenic and spatially organized polymicrobial communities that can cover large areas in the gastrointestinal tract. Gut microbiota dysbiosis, mucus disruption, and epithelial invasion are associated with pathogenic biofilms that have been linked to gastrointestinal disorders such as irritable bowel syndrome, inflammatory bowel diseases, gastric cancer, …
The transcription factor HIF-1α in NKp46+ ILCs limits chronic intestinal inflammation and fibrosis
Publication Year: 2024 Source: Life Sci Alliance PMID: 38876796
No Abstract
Psoriasis induced by antiTNF therapy in inflammatory bowel disease: Therapeutic management and evolution of both diseases in a nationwide cohort study
Publication Year: 2024 Source: Dig Liver Dis PMID: 38876834 DOI: 10.1016/j.dld.2024.05.021
BACKGROUND: some patients with inflammatory bowel disease (IBD) treated with antiTNF develop drug-induced psoriasis (antiTNF-IP). Several therapeutic strategies are possible. AIMS: to assess the management of antiTNF-IP in IBD, and its impact in both diseases. METHODS: patients with antiTNF-IP from ENEIDA registry were included. Therapeutic strategy was classified as continuing …
Effectiveness of a novel diet in attenuation of clinical activity of disease in patients with ulcerative colitis: a randomized, clinical trial
Publication Year: 2024 Source: Sci Rep PMID: 38877032 DOI: 10.1038/s41598-024-64512-8
Dietary intake plays a pivotal role in ulcerative colitis (UC) initiation and prognosis. The aim of this study was to investigate the effect of a combined Mediterranean, low-FODMAP diet accompanied with partial enteral nutrition (PEN) on clinical and para-clinical characteristics of patients with UC. Fifty patients with active mild to …
Thrombospondin 2, matrix Gla protein and digital analysis identified distinct fibroblast populations in fibrostenosing Crohn's disease
Publication Year: 2024 Source: Sci Rep PMID: 38877292
No Abstract
Reactive Immunomodulator Addition to Infliximab Monotherapy Restores Clinical Response in Inflammatory Bowel Disease: A Meta-Analysis
Publication Year: 2024 Source: Dig Dis Sci PMID: 38877332 DOI: 10.1007/s10620-024-08515-5
BACKGROUND AND AIMS: Patients with inflammatory bowel disease (IBD) receiving infliximab (IFX) commonly experience immunogenic loss of response (LOR) by formation of anti-drug antibodies (ADAs). An immunomodulator (IMM) used in combination with initial IFX induction is known to reduce ADA development and improve clinical outcomes. We aimed to assess the …
YTHDC1 inhibits autophagy-dependent NF-κB signaling by stabilizing Beclin1 mRNA in macrophages
Publication Year: 2024 Source: J Inflamm (Lond) PMID: 38877444 DOI: 10.1186/s12950-024-00393-y
BACKGROUND: YTHDC1, a key m(6)A nuclear reader, plays a crucial role in regulating mRNA splicing, export, and stability. However, the functional significance and regulatory mechanisms of YTHDC1 in inflammatory bowel disease (IBD) remain to be explored. METHODS: We established a dextran sulfate sodium (DSS)-induced murine colitis model in vivo and …
Gut microbiome and cardiometabolic comorbidities in people living with HIV
Publication Year: 2024 Source: Microbiome PMID: 38877521
No Abstract
Neutrophils: Old cells in IBD, new actors in interactions with the gut microbiota
Publication Year: 2024 Source: Clin Transl Med PMID: 38877640 DOI: 10.1002/ctm2.1739
No Abstract
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