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Giardia intestinalis reshapes mucosal immunity toward a Type 2 response that attenuates inflammatory bowel-like diseases
Publication Year: 2024 Source: bioRxiv PMID: 38903060
No Abstract
IL-21 conditions antigen-presenting human γδ T-cells to promote IL-10 expression in naïve and memory CD4(+) T-cells
Publication Year: 2024 Source: Discov Immunol PMID: 38903247
No Abstract
Individual Bilateral Difference of Femur, Tibia, and Leg Rotation: A Clinical Study of 141 Healthy Japanese Individuals Using Computed Tomography
Publication Year: 2024 Source: Cureus PMID: 38903376 DOI: 10.7759/cureus.60750
Background The malrotation of a femur and tibial fracture after surgery has been described in many articles. However, these studies have not considered individual bilateral differences (IBDs). The IBD of femur and tibial rotation has been identified via computed tomography (CT) in recent American studies. The IBD in rotation should …
Real-world effectiveness of upadacitinib in Crohn's disease: a UK multicentre retrospective cohort study
Publication Year: 2024 Source: Frontline Gastroenterol PMID: 38903490
No Abstract
Editorial: Gut dysbiosis-induced systemic inflammation in neurological diseases and disorders
Publication Year: 2024 Source: Front Immunol PMID: 38903516 DOI: 10.3389/fimmu.2024.1437651
No Abstract
Radiomics-Based Analysis of Intestinal Ultrasound Images for Inflammatory Bowel Disease: A Feasibility Study
Publication Year: 2024 Source: Crohns Colitis 360 PMID: 38903657 DOI: 10.1093/crocol/otae034
BACKGROUND: The increasing adoption of intestinal ultrasound (IUS) for monitoring inflammatory bowel diseases (IBD) by IBD providers has uncovered new challenges regarding standardized image interpretation and limitations as a research tool. Artificial intelligence approaches can help address these challenges. We aim to determine the feasibility of radiomic analysis of IUS …
Clinical characteristics and the risk factors for the exacerbation of symptoms in patients with inflammatory bowel disease during the COVID-19 pandemic
Publication Year: 2024 Source: Front Med (Lausanne) PMID: 38903816 DOI: 10.3389/fmed.2024.1404880
BACKGROUND: In 2023, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant caused a large-scale outbreak of coronavirus disease 2019 (COVID-19) in China. It is not clear the risk factors that lead to the exacerbation of symptoms in patients with inflammatory bowel disease (IBD) after COVID-19 infection. Our study …
Macrophagic HDAC3 inhibition ameliorates Dextran Sulfate Sodium induced inflammatory bowel disease through GBP5-NLRP3 pathway
Publication Year: 2024 Source: Int J Med Sci PMID: 38903915 DOI: 10.7150/ijms.94592
Inflammatory bowel disease (IBD) is a chronic inflammatory intestinal disease, characterized by dysregulated immune response. HDAC3 is reported to be an epigenetic brake in inflammation, playing critical roles in macrophages. However, its role in IBD is unclear. In our study, we found HDAC3 was upregulated in CX3CR1-positive cells in the …
Mendelian randomization unraveled: gender-specific insights into obesity-related phenotypes and colorectal cancer susceptibility
Publication Year: 2024 Source: Front Endocrinol (Lausanne) PMID: 38904048
No Abstract
Targeting TYK2 for Fighting Diseases: Recent Advance of TYK2 Inhibitors
Publication Year: 2024 Source: Curr Med Chem PMID: 38904160
No Abstract
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