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Immunogenicity of Hepatitis B Vaccination in Patients with Ulcerative Colitis on Infliximab Is Attenuated Compared to Those on 5-Aminosalicylic Acid Therapies: A Prospective Observational Study
Publication Year: 2024 Source: Vaccines (Basel) PMID: 38675746 DOI: 10.3390/vaccines12040364
INTRODUCTION: Hepatitis B virus (HBV) infection has been associated with chronic hepatitis and cirrhosis. Patients with inflammatory bowel disease (IBD) may be at a higher risk of HBV infection reactivation, especially those on biologic therapies. This study intends to compare the effectiveness of the HBV vaccine in patients with ulcerative …
The Effects of Endosomal Toll-like Receptor Inhibitors in an EBV DNA-Exacerbated Inflammatory Bowel Disease Mouse Model
Publication Year: 2024 Source: Viruses PMID: 38675965 DOI: 10.3390/v16040624
Epstein-Barr virus (EBV), a Herpesviridae family member, is associated with an increased risk of autoimmune disease development in the host. We previously demonstrated that EBV DNA elevates levels of the pro-inflammatory cytokine IL-17A and that inhibiting Toll-like receptor (TLR) 3, 7, or 9 reduces its levels. Moreover, this DNA exacerbated …
SARS-CoV-2 Omicron BA.1 Variant Infection of Human Colon Epithelial Cells
Publication Year: 2024 Source: Viruses PMID: 38675974
No Abstract
An Adaptive Multi-D-Norm-Driven Sparse Unfolding Deconvolutional Network for Bearing Fault Diagnosis
Publication Year: 2024 Source: Sensors (Basel) PMID: 38676240 DOI: 10.3390/s24082624
Impulsive blind deconvolution (IBD) is a popular method to recover impulsive sources for bearing fault diagnosis. Its underpinnings are in the design of objective functions based on prior knowledge of impulsive sources and a transfer function to describe transmission path influences. However, popular objective functions cannot retain waveform impulsiveness and …
Clostridioides difficile infection in inflammatory bowel disease: a clinical review
Publication Year: 2024 Source: Expert Rev Anti Infect Ther PMID: 38676422 DOI: 10.1080/14787210.2024.2347955
INTRODUCTION: Strong clinical data demonstrate that inflammatory bowel disease (IBD) is an independent risk factor for Clostridiodes difficile infection (CDI) and suggest a globally increased prevalence and severity of C. difficile coinfection in IBD patients (CDI-IBD). In addition to elderly individuals, children are also at higher risk of CDI-IBD. Rapid …
Comparison of diagnostic accuracy between linked color imaging and autofluorescence imaging in patients with ulcerative colitis: A prospective observational study
Publication Year: 2024 Source: J Gastroenterol Hepatol PMID: 38676457
No Abstract
Bear Bile Powder Improves Ulcerative Colitis by Protecting the Intestinal Mechanical Barrier and Regulating Intestinal Flora
Publication Year: 2024 Source: Curr Pharm Des PMID: 38676524
No Abstract
Benchmarking kinship estimation tools for ancient genomes using pedigree simulations
Publication Year: 2024 Source: Mol Ecol Resour PMID: 38676702 DOI: 10.1111/1755-0998.13960
There is growing interest in uncovering genetic kinship patterns in past societies using low-coverage palaeogenomes. Here, we benchmark four tools for kinship estimation with such data: lcMLkin, NgsRelate, KIN, and READ, which differ in their input, IBD estimation methods, and statistical approaches. We used pedigree and ancient genome sequence simulations …
Trends in the prevalence and incidence of Crohn's disease in Japan and the United States
Publication Year: 2024 Source: Int J Colorectal Dis PMID: 38676760
No Abstract
Very-early-onset Inflammatory Bowel Disease in an Infant with a Partial RIPK1 Deletion
Publication Year: 2024 Source: J Clin Immunol PMID: 38676845 DOI: 10.1007/s10875-024-01707-8
The monogenic causes of very-early-onset inflammatory bowel disease (VEO-IBD) have been defined by genetic studies, which were usually related to primary immunodeficiencies. Receptor-interacting serine/threonine-protein kinase-1 (RIPK1) protein is an important signalling molecule in inflammation and cell death pathways. Its deficiency may lead to various clinical features linked to immunodeficiency and/or …
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