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Colorectal Neoplasia in the Setting of Inflammatory Bowel Disease
Publication Year: 2024 Source: Surg Clin North Am PMID: 38677829 DOI: 10.1016/j.suc.2023.12.006
Inflammatory bowel disease (IBD) is associated with an increased risk of colorectal cancer (colorectal adenocarcinoma [CRC]) compared with the general population. IBD-related CRC is related to poorer outcomes than non-IBD-related CRC, and it accounts for 10% to 15% of death in patients with IBD. As such, screening guidelines have been …
Surgical Emergencies in Inflammatory Bowel Disease
Publication Year: 2024 Source: Surg Clin North Am PMID: 38677830 DOI: 10.1016/j.suc.2023.11.012
Inflammatory bowel disease (IBD) patients are at risk for undergoing emergency surgery for fulminant disease, toxic megacolon, bowel perforation, intestinal obstruction, or uncontrolled gastrointestinal hemorrhage. Unfortunately, medical advancements have failed to significantly decrease rates of emergency surgery for IBD. It is therefore important for all acute care and colorectal surgeons …
Prenatal exposure to environmental contaminants and cord serum metabolite profiles in future immune-mediated diseases
Publication Year: 2024 Source: J Expo Sci Environ Epidemiol PMID: 38678133 DOI: 10.1038/s41370-024-00680-z
BACKGROUND: Prenatal exposure to environmental contaminants is a significant health concern because it has the potential to interfere with host metabolism, leading to adverse health effects in early childhood and later in life. Growing evidence suggests that genetic and environmental factors, as well as their interactions, play a significant role …
DIREN mitigates DSS-induced colitis in mice and attenuates collagen deposition via inhibiting the Wnt/β-catenin and focal adhesion pathways
Publication Year: 2024 Source: Biomed Pharmacother PMID: 38678963
No Abstract
Alleviative effects of sulfated polysaccharide from Ishige Okamurae against DSS-induced ulcerative colitis via inhibiting inflammation and modulating gut microbiota
Publication Year: 2024 Source: Int J Biol Macromol PMID: 38679254
No Abstract
Construction of hyaluronic acid-functionalized magnolol nanoparticles for ulcerative colitis treatment
Publication Year: 2024 Source: Int J Biol Macromol PMID: 38679261
No Abstract
Fat and proteolysis due to methionine, tryptophan, and niacin deficiency leads to alterations in gut microbiota and immune modulation in inflammatory bowel disease
Publication Year: 2024 Source: Cancer Sci PMID: 38679799 DOI: 10.1111/cas.16153
Inflammatory bowel disease (IBD) is one of the intractable diseases. Nutritional components associated with IBD have been identified, and it is known that excessive methionine intake exacerbates inflammation, and that tryptophan metabolism is involved in inflammation. Analysis of the gut microbiota has also progressed, where Lactobacillus regulate immune cells in …
Long-term effectiveness and persistence rate of ustekinumab dose intensification in a South East Asian inflammatory bowel disease center
Publication Year: 2024 Source: J Gastroenterol Hepatol PMID: 38680014 DOI: 10.1111/jgh.16562
BACKGROUND AND AIMS: Ustekinumab (UST) is an effective biologic for treatment of inflammatory bowel disease (IBD). However, some patients treated with UST have suboptimal clinical response with standard dosing. The aims of this study were to determine the effectiveness of UST dose intensification (DI), identify factors associated with DI, cumulative …
Corticosteroid-Free Remission in Patients With Inflammatory Bowel Disease
Publication Year: 2024 Source: Gastroenterol Hepatol (N Y) PMID: 38680172
No Abstract
Modified Gwakjeongtang for Diarrhea-Predominant Irritable Bowel Syndrome: Study Protocol for a Randomized, Double-Blind, Placebo-Controlled, Pilot Clinical Trial
Publication Year: 2024 Source: Int J Gen Med PMID: 38680195
No Abstract
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