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Fecal proteolytic profiling of pediatric inflammatory bowel disease: A pilot study

Publication Year: 2024 Source: FASEB J PMID: 38690708 DOI: 10.1096/fj.202302190R

Colonoscopy is the gold standard for diagnosing inflammatory bowel disease (IBD). However, this invasive procedure has a high burden for pediatric patients. Previous research has shown elevated fecal amino acid concentrations in children with IBD versus controls. We hypothesized that this finding could result from increased proteolytic activity. Therefore, the …

A step closer to understanding how a diet high in simple carbohydrates may cause dysbiosis

Publication Year: 2024 Source: J Clin Invest PMID: 38690730 DOI: 10.1172/JCI180001

The gut microbiota is an integral part of the human metaorganism that is required to shape physiologic host immune responses including host defense against pathogens. Disease-associated gut dysbiosis has been characterized by blooms of pathobionts, which are bacterial species that can drive disease under certain conditions. Pathobionts like Enterobacteriaceae often …

Cytomegalovirus Infection in Adult Patients with Inflammatory Bowel Disease: A Literature Review

Publication Year: 2024 Source: Arch Iran Med PMID: 38690795 DOI: 10.34172/aim.2024.40

Human cytomegalovirus (HCMV) is classified within the Herpesvirales order and is prevalent in 50%‒80% of the general population. Most carriers experience this infection without noticeable clinical symptoms. HCMV causes a lifelong latent infection that can be reactivated due to immune disorders and inflammation. The reactivation of HCMV becomes particularly significant …

Fibrostricturing Crohn's Disease Is Marked by an Increase in Active Eosinophils in the Deeper Layers

Publication Year: 2024 Source: Clin Transl Gastroenterol PMID: 38690831

No Abstract

Classification for Reoperative Ileal Pouch Surgery

Publication Year: 2024 Source: Dis Colon Rectum PMID: 38690840 DOI: 10.1097/DCR.0000000000003264

No Abstract

Ocular lesions in patients with ulcerative colitis

Publication Year: 2024 Source: Wiad Lek PMID: 38691785

No Abstract

Study on the Protective Effect and Mechanism of Umbilicaria esculenta Polysaccharide in DSS-Induced Mice Colitis and Secondary Liver Injury

Publication Year: 2024 Source: J Agric Food Chem PMID: 38691832

No Abstract

Anti-inflammatory and protective effects of Aripiprazole on TNBS-Induced colitis and associated depression in rats: Role of kynurenine pathway

Publication Year: 2024 Source: Int Immunopharmacol PMID: 38691917 DOI: 10.1016/j.intimp.2024.112158

BACKGROUND: The prevalence of depression is higher in patients with inflammatory bowel disease (IBD) than in the general population. Inflammatory cytokines and the kynurenine pathway (KP) play important roles in IBD and associated depression. Aripiprazole (ARP), an atypical antipsychotic, shows various anti-inflammatory properties and may be useful in treating major …

Inflammatory bowel disease alters in vivo distribution of orally administrated nanoparticles: Revealing via SERS tag labeling technique

Publication Year: 2024 Source: Talanta PMID: 38692050 DOI: 10.1016/j.talanta.2024.126172

Nanoparticles (NPs) could be uptake orally and exposed to digestive tract through various sources such as particulate pollutant, nanomedicine and food additive. Inflammatory bowel disease (IBD), as a global disease, induced disruption of the intestinal mucosal barrier and thus altered in vivo distribution of NPs as a possible consequence. However, …

Threadlike linear calcifications along the proximal colon of a 71-year-old woman with chronic abdominal pain

Publication Year: 2024 Source: Gastrointest Endosc PMID: 38692520

No Abstract

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