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Food for thought: Making the case for food produced via regenerative agriculture in the battle against non-communicable chronic diseases (NCDs)

Publication Year: 2024 Source: One Health PMID: 38711478

No Abstract

The causal relationship between sarcoidosis and autoimmune diseases: a bidirectional Mendelian randomization study in FinnGen

Publication Year: 2024 Source: Front Immunol PMID: 38711527 DOI: 10.3389/fimmu.2024.1325127

BACKGROUND: Sarcoidosis has been considered to be associated with many autoimmune diseases (ADs), but the cause-and-effect relationship between these two diseases has not been fully explored. Therefore, the objective of this study is to explore the possible genetic association between sarcoidosis and ADs. METHODS: We conducted a bidirectional Mendelian randomization …

Effectiveness and Persistency of Ustekinumab Treatment for Ulcerative Colitis: A Phoenix retrospective Cohort Study

Publication Year: 2024 Source: Crohns Colitis 360 PMID: 38711858

No Abstract

Halitosis: an underestimated but important extraintestinal manifestation in inflammatory bowel disease

Publication Year: 2024 Source: Intest Res PMID: 38712358

No Abstract

Defining management strategies for acute severe ulcerative colitis using predictive models: a simulation-modeling study

Publication Year: 2024 Source: Intest Res PMID: 38712360

No Abstract

Efficacy of serum leucine-rich alpha-2 glycoprotein in predicting findings of Crohn's disease small bowel lesion in capsule endoscopy

Publication Year: 2024 Source: Intest Res PMID: 38712361

No Abstract

Immunomodulatory effects of extracellular vesicles from mesenchymal stromal cells: Implication for therapeutic approach in autoimmune diseases

Publication Year: 2024 Source: Kaohsiung J Med Sci PMID: 38712483 DOI: 10.1002/kjm2.12841

Autoimmune disease is characterized by the proliferation of harmful immune cells, inducing tissue inflammation and ultimately causing organ damage. Current treatments often lack specificity, necessitating high doses, prolonged usage, and high recurrence rates. Therefore, the identification of innovative and safe therapeutic strategies is urgently required. Recent preclinical studies and clinical …

Evaluating the pharmacokinetics of upadacitinib for the treatment of moderate-to-severe Crohn's disease

Publication Year: 2024 Source: Expert Opin Drug Metab Toxicol PMID: 38712496 DOI: 10.1080/17425255.2024.2349711

INTRODUCTION: Janus kinases (JAK) are enzymes involved in signaling pathways that activate the immune system. Upadacitinib, an oral small molecule, is the first JAK inhibitor approved by FDA and EMA for the treatment of moderately to severely active Crohn's disease (CD), following successful phase II and III trials. Compared to …

Infliximab modifies CD74-mediated lymphatic abnormalities and adipose tissue alterations in creeping fat of Crohn's disease

Publication Year: 2024 Source: Inflamm Res PMID: 38713235

No Abstract

Monoclonal Antibodies Against Mature Interleukin-18 Ameliorate Colitis and Repair Goblet Cell Function

Publication Year: 2024 Source: Dig Dis Sci PMID: 38713271

No Abstract

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