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Perineal wound morbidity following proctectomy for inflammatory bowel disease (IBD)
Publication Year: 2000 Source: Colorectal Dis PMID: 23578042 DOI: 10.1046/j.1463-1318.2000.00150.x
Comment in Br J Surg. 1999 Aug;86(8):1096-7; author reply 1097-8. Br J Surg. 1999 Aug;86(8):1097-8. BACKGROUND: An artificial anal sphincter has been developed which aimed to simulate the normal physiology of the anorectum. As a prelude to human implantation the present study reports the effect of inflation of this device …
Effects of trimetazidine in ethanol- and acetic acid-induced colitis: oxidant/anti-oxidant status
Publication Year: 1999 Source: Colorectal Dis PMID: 23574598 DOI: 10.1046/j.1463-1318.1999.00078.x
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Aberrant mucosal cytokines: the key to the pathogenesis of IBD?
Publication Year: 1999 Source: Inflamm Bowel Dis PMID: 10338386 DOI: 10.1097/00054725-199905000-00014
Comment in Gut. 2010 Oct;59(10):1310-1. Gastroenterology. 2011 Jan;140(1):360-2; discussion 362-3. Inflamm Bowel Dis. 2011 Nov;17(11):2404-5. BACKGROUND: There is no information about the frequency of liver dysfunction in patients with inflammatory bowel disease (IBD) treated with immunosuppressants and infected with hepatitis B (HBV) and/or C virus (HCV). AIM: To assess the …
Citrobacter rodentium infection in mice elicits a mucosal Th1 cytokine response and lesions similar to those in murine inflammatory bowel disease
Publication Year: 1999 Source: Infect Immun PMID: 10338516 DOI: 10.1128/IAI.67.6.3031-3039.1999
Lipoprotein(a) (Lp(a)) is a complex in human plasma assembled from low-density lipoprotein (LDL) and apolipoprotein(a) (apo(a)). High plasma concentrations of Lp(a) are a risk factor for coronary heart disease (CHD) in particular in patients with concomitant elevation of LDL. We have analysed for elevated Lp(a) levels in patients with familial …
Complementary and alternative medicine use by patients with inflammatory bowel disease: An Internet survey
Publication Year: 1999 Source: Can J Gastroenterol PMID: 10360993 DOI: 10.1155/1999/586765
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Mucosal immunity and inflammation. II. The yin and yang of T cells in intestinal inflammation: pathogenic and protective roles in a mouse colitis model
Publication Year: 1999 Source: Am J Physiol PMID: 10362634 DOI: 10.1152/ajpgi.1999.276.6.G1317
Scid mice transplanted either with a gut wall graft or with low numbers of purified CD4+ T cells from immunocompetent syngeneic donor mice show clinical signs of IBD 3-4 months post-transplantation. The disease is mediated by mucosa-infiltrating CD4+ TCR alphabeta+ T cells. The pathology of 52 individual colon segments obtained …
Epstein-Barr virus infection of the colon with inflammatory bowel disease
Publication Year: 1999 Source: Am J Gastroenterol PMID: 10364028 DOI: 10.1111/j.1572-0241.1999.01148.x
Anecdotal reports suggest that smoking may be beneficial for patients with inflammatory bowel disease (IBD) as nicotine may act through inflammatory mediators within the colonic mucosa. Furthermore, there is increasing evidence that cytokines play a pathologic role in IBD. Our aim was to determine the effects of cigarette smoking on …
Intravenous cyclosporin in ulcerative colitis: a five-year experience
Publication Year: 1999 Source: Am J Gastroenterol PMID: 10364029 DOI: 10.1111/j.1572-0241.1999.01149.x
Eupodia are F-actin-containing cortical structures similar to vertebrate podosomes or invadopodia found in metastatic cells. Eupodia are rich in alpha-actinin and myosin IB/D, but not a Dictyostelium homologue of talin. In the present study, we localized other actin-binding proteins, ABP120, cofilin, coronin, and fimbrin, in the eupodia and examined the …
Simultaneous presentation of coeliac disease and ulcerative colitis in a child
Publication Year: 1999 Source: J Paediatr Child Health PMID: 10365362 DOI: 10.1046/j.1440-1754.1999.t01-1-00328.x
Comment in Am J Gastroenterol. 2011 Nov;106(11):2042; author reply 2042-3. OBJECTIVES: Patients with inflammatory bowel disease (IBD) present with several extraintestinal manifestations, including systemic inflammation and hypercoagulability. Limited studies have shown that patients with IBD may have a higher risk of developing atherosclerosis. The incidence of coronary artery disease (CAD) …
The role of IL-10 in inflammatory bowel disease: "of mice and men"
Publication Year: 1999 Source: Toxicol Pathol PMID: 10367687 DOI: 10.1177/019262339902700124
OBJECTIVE: Our aim was to study the frequency, severity, and outcome of patients with Crohn's disease and ulcerative colitis treated with 6-mercaptopurine (6MP) who developed shingles during treatment, and to recommend management. While varicella can be severe in young people immunocompromised by steroids, the incidence of herpes zoster in older …
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