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Expression of pro-inflammatory cytokines by TCR alpha beta+ and TCR gamma delta+ T cells in an experimental model of colitis
Publication Year: 1997 Source: Eur J Immunol PMID: 9021993 DOI: 10.1002/eji.1830270104
Inflammatory bowel disease (IBD), most commonly referring to Crohn's disease and ulcerative colitis, is a chronic and disabling condition with an increasing incidence in southern Europe. The etiology of IBD remains unknown, but the characteristic disproportionate inflammatory response in the gut may develop through various mechanisms at the cellular and …
Dairy sensitivity, lactose malabsorption, and elimination diets in inflammatory bowel disease
Publication Year: 1997 Source: Am J Clin Nutr PMID: 9022546 DOI: 10.1093/ajcn/65.2.564
Crohn's disease and ulcerative colitis are chronic inflammatory gastrointestinal disorders which often result in significant morbidity or surgery. Current treatment options are not curative and may cause significant adverse effects. The introduction of anti-tumour necrosis factor alpha (anti-TNFα) therapy over a decade ago was a welcome addition to the therapeutic …
Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice
Publication Year: 1997 Source: Clin Exp Immunol PMID: 9030875 DOI: 10.1111/j.1365-2249.1997.291-ce1184.x
A high-fat and low-fiber diet is regarded as a major risk factor for colon cancer by increasing luminal contents of secondary bile acids. Calcium, on the other hand, has been implicated as a possible preventive agent in colon tumor development. In in vitro studies with human colonic epithelium, incubation with …
Disassociation between the in vitro and in vivo effects of nitric oxide on a neurotropic murine coronavirus
Publication Year: 1997 Source: J Virol PMID: 9032354 DOI: 10.1128/JVI.71.3.2202-2210.1997
Erratum in Nat Genet. 2011 Apr;43(4):388. Ulcerative colitis is a chronic, relapsing inflammatory condition of the gastrointestinal tract with a complex genetic and environmental etiology. In an effort to identify genetic variation underlying ulcerative colitis risk, we present two distinct genome-wide association studies of ulcerative colitis and their joint analysis …
Increased eosinophil granule proteins in gut lavage fluid from patients with inflammatory bowel disease
Publication Year: 1997 Source: Mayo Clin Proc PMID: 9033543 DOI: 10.4065/72.2.117
OBJECTIVES: To explore the relationships between vitamin D intake, serum parathyroid hormone (PTH) and 25-hydroxyvitamin D (250HD) concentrations, and bone mineral density (BMD) in inflammatory bowel disease (IBD). SETTING: A university hospital clinic in Finland. SUBJECTS: One hundred and fifty randomly selected patients with IBD from the hospital register and …
Eating attitudes and the irritable bowel syndrome
Publication Year: 1997 Source: Gen Hosp Psychiatry PMID: 9034814 DOI: 10.1016/s0163-8343(96)00106-5
Part II of this two-part article (See The American Journal of Surgery 1992; 164: 85-9) reviews the current definition of the role of immunosuppressive therapy in inflammatory bowel disease (IBD) and the use of antibiotics in IBD, as well as summarizes the uses of the new agents on the horizon …
Problems in diagnosis of IBD in children
Publication Year: 1997 Source: Neth J Med PMID: 9050326 DOI: 10.1016/s0300-2977(96)00064-2
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Refractory IBD: medical management
Publication Year: 1997 Source: Neth J Med PMID: 9050327 DOI: 10.1016/s0300-2977(96)00065-4
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The fascination of IBD
Publication Year: 1997 Source: Neth J Med PMID: 9050331 DOI: 10.1016/s0300-2977(96)00069-1
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Inflammatory bowel diseases with onset in childhood. Clinical features, morbidity, and mortality in a regional cohort
Publication Year: 1997 Source: Scand J Gastroenterol PMID: 9051874 DOI: 10.3109/00365529709000184
PURPOSE: We have used a novel leukocyte adhesiveness/aggregation test (LAAT) to show that many patients with inflammatory bowel disease (IBD) in clinical remission have a subclinical low grade inflammation. METHODS: Included in the study are 500 controls, 96 patients with IBD in remission, and 106 patients in relapse. RESULTS: The …
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