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Application of a colon delivery capsule to 5-aminosalicylic acid and evaluation of the pharmacokinetic profile after oral administration to beagle dogs
Publication Year: 1997 Source: J Drug Target PMID: 9169983 DOI: 10.3109/10611869708995842
Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation whose cellular components are capable of oxidative respiratory bursts that may result in tissue injury. Mucosal biopsies were analyzed for protein carbonyl content (POPs), DNA oxidation products [8-hydroxy-2'-deoxyguanosine (8-OHdG)], reactive oxygen intermediates (ROIs), trace metals (copper, zinc, and iron) and …
Role of cell adhesion molecules in inflammatory bowel diseases
Publication Year: 1997 Source: Scand J Gastroenterol PMID: 9175198 DOI: 10.3109/00365529709025072
Theoretical advantages of nonparametric logarithm of odds to map polygenic diseases are supported by tests of the beta model that depends on a single logistic parameter and is the only model under which paternal and maternal transmissions to sibs of specified phenotypes are independent. Although it does not precisely describe …
Gastro-entero-hepatology in the next millennium
Publication Year: 1997 Source: Neth J Med PMID: 9175405 DOI: 10.1016/s0300-2977(97)00015-6
Amebic colitis needs to be considered in the differential diagnosis of infectious colitis or inflammatory bowel disease (IBD). Misdiagnosing amebic colitis as idiopathic inflammatory disease may be fatal. Although stool studies remain the initial approach to diagnosis, the incidence of false-negatives associated with this method is high. We report two …
CD4+ T-cell population mediates development of inflammatory bowel disease in T-cell receptor alpha chain-deficient mice
Publication Year: 1997 Source: Gastroenterology PMID: 9178680 DOI: 10.1053/gast.1997.v112.pm9178680
Comment in Gastroenterology. 1992 Jun;102(6):2164-5. Intraocular pressure (IOP) was measured in 54 pediatric patients (aged 7-21 years) with inflammatory bowel disease (IBD) who were treated with oral prednisone for 1-104 months. The difference in mean IOP between the treated patients (mean +/- SD, 15.62 +/- 4.11 mm Hg) and 55 …
IBD-associated bone loss: is inflammation the explanation?
Publication Year: 1997 Source: Gastroenterology PMID: 9178718 DOI: 10.1053/gast.1997.v112.agast972161a
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Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q
Publication Year: 1997 Source: Am J Med Genet PMID: 9184307 DOI: 10.1002/(sici)1096-8628(19970531)74:3<254::aid-ajmg4>3.0.co;2-q
Not found
Relationship between ANCA and clinical activity in inflammatory bowel disease: variation in prevalence of ANCA and evidence of heterogeneity
Publication Year: 1997 Source: J Autoimmun PMID: 9185879 DOI: 10.1006/jaut.1996.0114
Republished from Gastroenterol Clin North Am. 2009 Dec;38(4):691-709. Over the last decade, the medical treatment of inflammatory bowel disease (IBD) has been revolutionized, with increasing use of both immunomodulatory and biologic medications. Corticosteroids have increasingly been shown to increase the risk of serious and opportunistic infections, both independently and in …
Orthotopic liver transplantation for primary sclerosing cholangitis. A 12-year single center experience
Publication Year: 1997 Source: Ann Surg PMID: 9193175 DOI: 10.1097/00000658-199705000-00004
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Evaluation of the role of neutrophils in the pathogenesis of acetic acid-induced colitis in mice
Publication Year: 1997 Source: Scand J Gastroenterol PMID: 9200288 DOI: 10.3109/00365529709025100
Erratum in Digestion 1998;59(1):90. BACKGROUND/AIMS: We evaluated the effects of an antagonist of the thromboxane A2 receptor (ONO-NT-126) in an animal model of inflammatory bowel disease (IBD). METHODS: Colitis was induced by intracolonic instillation of trinitrobenzenesulfonic acid/ethanol in male Wistar rats. ONO-NT-126 or vehicle alone was administered intraluminally via anus …
mRNA differential display of colonic mucosa cells in ulcerative colitis
Publication Year: 1997 Source: J Surg Res PMID: 9202657 DOI: 10.1006/jsre.1997.5041
Despite extensive research, the pathogenesis of inflammatory bowel disease (IBD) is still unclear. Immunological disorders have been described in patients with both Crohn's disease (CD) and ulcerative colitis (UC). In this work serum samples collected from 58 patients with CD and 55 patients with UC were tested in ELISA against …
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