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A randomized, placebo-controlled trial of calcium supplementation for decreased bone density in corticosteroid-using patients with inflammatory bowel disease: a pilot study

Publication Year: 1996 Source: Aliment Pharmacol Ther PMID: 8899087 DOI: 10.1046/j.1365-2036.1996.63205000.x

The identification of susceptibility genes for inflammatory bowel disease (IBD) is key to understanding pathogenic mechanisms. Recently, the results of genetic association studies have highlighted many loci that are shared among several autoimmune diseases. We aimed to study the genetic epidemiology of polymorphisms in specific genes previously associated with other …

Interleukin-1 and interleukin-1 receptor antagonist in inflammatory bowel disease

Publication Year: 1996 Source: Aliment Pharmacol Ther PMID: 8899101 DOI: 10.1046/j.1365-2036.1996.22164020.x

BACKGROUND: The outcome of restorative proctocolectomy in the setting of chronic ulcerative colitis complicated by primary sclerosing cholangitis (PSC) is not clear. The purpose of this study was to determine the surgical outcome, risk of dysplasia/cancer, morbidity/mortality, long-term results, and functional and quality of life results in patients with inflammatory …

Primary sclerosing cholangitis in Japanese patients: association with inflammatory bowel disease

Publication Year: 1996 Source: Acta Med Okayama PMID: 8914675 DOI: 10.18926/AMO/30499

Inflammatory bowel disease (IBD) has the propensity to affect patients who are in their late teens and early 20s, an age when most people decide on their educational and career directions. This review describes the effects that IBD has on the continuum of education and employment. Patients with Crohn's disease …

An improved multipoint sib-pair analysis of quantitative traits

Publication Year: 1996 Source: Behav Genet PMID: 8917952 DOI: 10.1007/BF02359758

Health-Related Quality of Life (HRQOL) measurement has become a key element in the assessment of chronic diseases during the execution of clinical research and in the delivery of health care. Poor HRQOL is clearly recognized in patients with inflammatory bowel disease (IBD) and relates to the type of disease (Crohn's …

Alteration of a polyclonal to an oligoclonal immune response to cecal aerobic bacterial antigens in TCR alpha mutant mice with inflammatory bowel disease

Publication Year: 1996 Source: Int Immunol PMID: 8921416 DOI: 10.1093/intimm/8.9.1387

Not found

Incidence of inflammatory bowel disease in Italy: a nationwide population-based study. Gruppo Italiano per lo Studio del Colon e del Retto (GISC)

Publication Year: 1996 Source: Int J Epidemiol PMID: 8921493 DOI: 10.1093/ije/25.5.1044

Not found

Cigarette smoking and quality of life in patients with inflammatory bowel disease. South Limburg IBD Study Group

Publication Year: 1996 Source: Eur J Gastroenterol Hepatol PMID: 8944369 DOI: 10.1097/00042737-199611000-00009

Not found

Dietary calcium intake and its relation to bone mineral density in patients with inflammatory bowel disease

Publication Year: 1996 Source: J Intern Med PMID: 8946811 DOI: 10.1046/j.1365-2796.1996.25862000.x

Not found

6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity

Publication Year: 1996 Source: Gut PMID: 8949645 DOI: 10.1136/gut.39.3.401

BACKGROUND: Tumor necrosis factor alpha (TNF alpha) and beta (TNF beta) appear to play an important role in the regulation of the inflammatory response. The aim of the present study was to investigate the intrinsic capacity of peripheral blood mononuclear cells (PBMC) to produce these cytokines. METHODS: PBMC from 41 …

The role of gut inflammation in the pathogenesis of spondyloarthropathies

Publication Year: 1996 Source: Acta Clin Belg PMID: 8950841 DOI: 10.1080/22953337.1996.11718528

BACKGROUND: Anti-infliximab antibodies (ATIs) are associated with lower serum infliximab (IFX) trough levels and diminished clinical response. The current most prevalent method for detection of ATI is a double-antigen (DA) enzyme-linked immunosorbent assay (ELISA) utilizing IFX for ligand and detection antibody. Serum IFX interferes with ATI measurement in this method. …

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