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Protection against hypoxic-ischemic damage with corticosterone and dexamethasone: inhibition of effect by a glucocorticoid antagonist RU38486

Publication Year: 1996 Source: Brain Res PMID: 9017253 DOI: 10.1016/s0006-8993(96)01054-2

PURPOSE: Pouch-vaginal fistula is an uncommon but serious complication after ileal pouch anal anastomosis. The management of pouch-vaginal fistulas is challenging and a number of treatment options exist. The purpose of this study was to examine the outcomes after various procedures for pouch-vaginal fistula performed at our institution. METHODS: Patients …

Alterations of the mucosal immune system in inflammatory bowel disease

Publication Year: 1996 Source: J Gastroenterol PMID: 9027661 DOI: 10.1007/BF02358624

BACKGROUND & AIMS: Genetic polymorphism in thiopurine methyltransferase (TPMT) activity may influence clinical responsiveness to azathioprine (AZA) therapy. Our aim was to determine if the measurement of erythrocyte TPMT enzyme activity could be used to optimize clinical responsiveness to AZA therapy in patients with inflammatory bowel disease (IBD). METHODS: A …

A longitudinal study of alexithymia and psychological distress in inflammatory bowel disease

Publication Year: 1996 Source: J Psychosom Res PMID: 9032720 DOI: 10.1016/s0022-3999(96)00221-8

Not found

The significance of low grade right iliac fossa uptake on 99Tcm-HMPAO labelled white cell scans

Publication Year: 1996 Source: Br J Radiol PMID: 9038526 DOI: 10.1259/0007-1285-69-826-914

ASLC is clinically and endoscopically similar to active idiopathic IBD, especially ulcerative colitis. While several histopathologic criteria have been described which are useful in distinguishing these conditions, the diagnosis can still be difficult. In this study, we review the use of immunofluorescence on formalin-fixed paraffin-embedded biopsies from patients with ASLC. …

Immunoregulatory properties of IL-13 in patients with inflammatory bowel disease; comparison with IL-4 and IL-10

Publication Year: 1996 Source: Clin Exp Immunol PMID: 9099934 DOI: 10.1046/j.1365-2249.1996.39750.x

Not found

CD4+ T lymphocytes injected into severe combined immunodeficient (SCID) mice lead to an inflammatory and lethal bowel disease

Publication Year: 1996 Source: Clin Exp Immunol PMID: 9099935 DOI: 10.1046/j.1365-2249.1996.48757.x

Not found

Are HLA-DR or TAP genes genetic markers of severity in ulcerative colitis?

Publication Year: 1996 Source: J Autoimmun PMID: 9115580 DOI: 10.1006/jaut.1996.0100

Comment in Am J Gastroenterol. 2008 Feb;103(2):397-8. INTRODUCTION: Antibodies to baker's yeast (mannan) have been widely used to aid in diagnosis of Crohn's disease. Recently, there has been interest in antibodies against a flagellin from Clostridium coccoides subphylum. We hypothesized that reactivity with these antigens is a surrogate marker for …

Hemostatic abnormalities in inflammatory bowel disease

Publication Year: 1996 Source: Thromb Res PMID: 9163067 DOI: 10.1016/0049-3848(96)00060-6

Neutrophils are important cellular mediators in inflammatory bowel disease (IBD). Interleukin (IL)8, a powerful neutrophil chemoattractant, is found in increased quantities in inflamed mucosa, but the cells of origin are uncertain. IL8 gene expression was studied by in situ hybridisation in uninflamed intestinal tissue resected for colon carcinoma (n = …

Introduction to eicosanoids and the gastroenteric tract

Publication Year: 1996 Source: Gastroenterol Clin North Am PMID: 9229572 DOI: 10.1016/s0889-8553(05)70246-6

Not found

Eicosanoids and inflammatory bowel disease

Publication Year: 1996 Source: Gastroenterol Clin North Am PMID: 9229575 DOI: 10.1016/s0889-8553(05)70249-1

The mothers of 72 children and adolescents with inflammatory bowel disease (IBD) and 44 mothers of children and adolescents with cystic fibrosis (CF) were given A-SADS interviews. Fifty-one percent of IBD mothers and 41% of cystic fibrosis mothers had a lifetime history of depression. More IBD than CF mothers had …

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