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Altered leukotriene B4 metabolism in colonic mucosa with inflammatory bowel disease

Publication Year: 1995 Source: Scand J Gastroenterol PMID: 7701249 DOI: 10.3109/00365529509093234

A characteristic pattern in the occupational distribution of idiopathic inflammatory bowel disease (IBD) could help to focus research with regard to its etiology or reveal the nature of possible environmental risk factors. The present study analyses occupational mortality from Crohn's disease and ulcerative colitis in England and Wales during 8 …

Influence of orthotopic liver transplantation on serum vitamin A levels in patients with chronic liver disease

Publication Year: 1995 Source: Scand J Gastroenterol PMID: 7701254 DOI: 10.3109/00365529509093238

BACKGROUND: Considering the controversial results published in the literature concerning associations between human leukocyte antigens (HLA) and rheumatic fever (RF), the purpose of the present study was to investigate by means of cosegregation analysis the participation of HLA genes in susceptibility to RF. METHODS AND RESULTS: The sample reported here …

Altered ascorbic acid status in the mucosa from inflammatory bowel disease patients

Publication Year: 1995 Source: Free Radic Res PMID: 7704184 DOI: 10.3109/10715769509147535

Immunoregulatory properties of cytokines may mediate disordered inflammatory events in ulcerative colitis (UC) and Crohn's disease (CD). In the present study, profiles of cytokines produced by activated macrophages were studied in colonic tissue from 43 patients with and without inflammatory bowel disease (IBD). Cytokine messenger RNA (mRNA) extracted from mucosal …

Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent

Publication Year: 1995 Source: Dig Dis Sci PMID: 7729284 DOI: 10.1007/BF02064182

PURPOSE: To compare the experiences of perceived stigma (PS) in both patients with irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) and examine its relationship to patient-reported outcomes in both patient populations. METHODS: IBD and IBS patients were recruited from an outpatient gastroenterology clinic and online via support message …

Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease

Publication Year: 1995 Source: Gastroenterology PMID: 7729636 DOI: 10.1016/0016-5085(95)90692-4

Inflammatory bowel disease (IBD) is a common condition in cats characterised by infiltration of inflammatory cells into the intestinal mucosa. In this study, real-time reverse transcriptase polymerase chain reaction (RT-PCR) was used to quantify cytokine messenger RNA (mRNA) expression in intestinal biopsies from cats. Biopsies were collected from seven cats …

Circulating granulocyte antibodies in first attacks of colitis

Publication Year: 1995 Source: Scand J Gastroenterol PMID: 7732339 DOI: 10.3109/00365529509093255

BACKGROUND & AIMS: Most previous population-based studies of mortality in inflammatory bowel disease (IBD) did not account for medication use. We evaluated mortality by IBD medication use among members of the Kaiser Permanente Northern California IBD Registry. METHODS: The retrospective, population-based cohort study included 9032 persons who received at least …

Lack of association between smoking and inflammatory bowel disease in Jewish patients in Israel

Publication Year: 1995 Source: Gastroenterology PMID: 7768372 DOI: 10.1016/0016-5085(95)90129-9

BACKGROUND: Antineutrophil cytoplasmic antibodies (ANCA) have recently been demonstrated in the sera of patients with inflammatory bowel disease (IBD). METHODS: The presence of ANCA was studied in 107 sera obtained during 1 year from 48 patients with a first attack of IBD and in 33 such sera from 19 patients …

Reverse passive haemagglutination test in the diagnosis of infectious bursal disease

Publication Year: 1995 Source: Trop Anim Health Prod PMID: 7770951 DOI: 10.1007/BF02236335

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A study of the histological criteria for ulcerative colitis: retrospective evaluation of multiple colonic biopsies

Publication Year: 1995 Source: J Gastroenterol PMID: 7773349 DOI: 10.1007/BF02348664

We compared sulphasalazine (SSZ) toxicity in 140 patients (196 treatment periods) of two patient groups, those with rheumatoid disease (RD) (rheumatoid arthritis, RA, ankylosing spondylitis, AS), and those with inflammatory bowel disease (IBD). Adverse events occurred in 64% of all patients (highest 85% in AS and lowest 50% in ulcerative …

Circulating antiinflammatory cytokine IL-10 in patients with inflammatory bowel disease (IBD)

Publication Year: 1995 Source: Clin Exp Immunol PMID: 7774055 DOI: 10.1111/j.1365-2249.1995.tb03721.x

An increase in splanchnic blood flow in both arterial and venous beds has been demonstrated in inflammatory bowel disease (IBD) by means of angiographic and scintigraphic studies. Doppler ultrasound (US) enables a non-invasive evaluation of splanchnic arterial inflow in the superior mesenteric artery (SMA) and of venous outflow in the …

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