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Vedolizumab and new-onset spondyloarthritis: Debunking the myth
Publication Year: 2024 Source: United European Gastroenterol J PMID: 38990708
No Abstract
Sex and age differences in inflammatory bowel disease patients; a nationwide study based on Iranian Registry of Crohn's and Colitis (IRCC)
Publication Year: 2024 Source: PLoS One PMID: 38990835 DOI: 10.1371/journal.pone.0304792
BACKGROUND: Despite the rising prevalence of Inflammatory Bowel Disease (IBD), age and sex differences in its outcomes remain understudied. We investigated age and sex differences in IBD patients using a nationwide study in Iran, the Iranian Registry of Crohn's and Colitis (IRCC). METHODS: The IRCC is a national registry that …
Abnormal expression of oxylipins and related synthesizing/signaling pathways in inflammatory bowel diseases
Publication Year: 2024 Source: Prostaglandins Leukot Essent Fatty Acids PMID: 38991597
No Abstract
The string sign in Crohn's disease
Publication Year: 2024 Source: Rev Gastroenterol Mex (Engl Ed) PMID: 38991919
No Abstract
Histopathology imaging and clinical data including remission status in pediatric inflammatory bowel disease
Publication Year: 2024 Source: Sci Data PMID: 38992012 DOI: 10.1038/s41597-024-03592-7
The incidence of inflammatory bowel disease (IBD) is increasing annually. Children with IBD often suffer significant morbidity due to physical and emotional effects of the disease and treatment. Corticosteroids, often a component of therapy, carry undesirable side effects with long term use. Steroid-free remission has become a standard for care-quality …
Astragalus mongholicus Bunge extract improves ulcerative colitis by promoting PLCB2 to inhibit colonic epithelial cell pyroptosis
Publication Year: 2024 Source: J Ethnopharmacol PMID: 38992398
No Abstract
Sinomenine hydrochloride improves DSS-induced colitis in mice through inhibition of the TLR2/NF-κB signaling pathway
Publication Year: 2024 Source: Clin Res Hepatol Gastroenterol PMID: 38992426
No Abstract
Western diet reduces small intestinal intraepithelial lymphocytes via FXR-Interferon pathway
Publication Year: 2024 Source: Mucosal Immunol PMID: 38992433 DOI: 10.1016/j.mucimm.2024.07.001
The prevalence of obesity in the United States has continued to increase over the past several decades. Understanding how diet-induced obesity modulates mucosal immunity is of clinical relevance. We previously showed that consumption of a high fat, high sugar "Western" diet (WD) reduces the density and function of small intestinal …
Gut Pathobiont-Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis-Associated Inflammatory Bowel Disease
Publication Year: 2024 Source: Gastroenterology PMID: 38992449 DOI: 10.1053/j.gastro.2024.06.032
BACKGROUND & AIMS: Primary sclerosing cholangitis (PSC), often associated with inflammatory bowel disease (IBD), presents a multifactorial etiology involving genetic, immunologic, and environmental factors. Gut dysbiosis and bacterial translocation have been implicated in PSC-IBD, yet the precise mechanisms underlying their pathogenesis remain elusive. Here, we describe the role of gut …
Synbiotics containing sea buckthorn polysaccharides ameliorate DSS-induced colitis in mice via regulating Th17/Treg homeostasis through intestinal microbiota and their production of BA metabolites and SCFAs
Publication Year: 2024 Source: Int J Biol Macromol PMID: 38992530 DOI: 10.1016/j.ijbiomac.2024.133794
Inflammatory Bowel Disease (IBD) is a chronic condition whose incidence has been rising globally. Synbiotic (SYN) is an effective means of preventing IBD. This study investigated the preventive effects and potential biological mechanisms of SYN (Bifidobacterium longum, Lactobacillus acidophilus, and sea buckthorn polysaccharides) on DSS-induced colitis in mice. The results …
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