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Platelets in ulcerative colitis and Crohn's disease express functional interleukin-1 and interleukin-8 receptors

Publication Year: 1994 Source: Eur J Clin Invest PMID: 7531643 DOI: 10.1111/j.1365-2362.1994.tb01057.x

Comment in Inflamm Bowel Dis. 2009 Mar;15(3):475-7. BACKGROUND & AIMS: The aim of this study was to determine whether pregnancy outcomes differ between women with and without inflammatory bowel disease (IBD) and to determine what risk factors adversely affect outcomes. METHODS: We conducted a cohort study of all pregnant women …

Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

Publication Year: 1994 Source: Immunity PMID: 7600284 DOI: 10.1016/1074-7613(94)90045-0

Not found

Pathogenesis of highly virulent infectious bursal disease virus infection in intact and bursectomized chickens

Publication Year: 1994 Source: J Vet Med Sci PMID: 7696392 DOI: 10.1292/jvms.56.1057

AIM: N-acetyltransferase 2 (NAT2) is an important enzyme catalyzing N-acetylation of sulfasalazine (SASP). The aim of the present study was to investigate associations of the genotypes of NAT2 with inflammatory bowel disease (IBD), and with adverse effects of SASP, which is used as the first-line treatment of IBD. PATIENTS AND …

Colonic mucosal interleukin 1 receptor antagonist in inflammatory bowel disease

Publication Year: 1994 Source: Digestion PMID: 7705549 DOI: 10.1159/000201167

Not found

Carcinoid tumour complicating inflammatory bowel disease. A study of two cases with review of the literature

Publication Year: 1994 Source: Pathol Res Pract PMID: 7792207 DOI: 10.1016/S0344-0338(11)80445-0

To test the hypothesis that environmental factors play a role in idiopathic inflammatory bowel disease (IBD), age, period, and generation (cohort) effects on IBD mortality in the United Kingdom and the United States were examined. The crude death rate of ulcerative colitis has declined since 1930. Plotted versus the year …

Side effects of sulphasalazine in patients with rheumatic diseases or inflammatory bowel disease

Publication Year: 1994 Source: Scand J Rheumatol PMID: 7801059 DOI: 10.3109/03009749409099284

To investigate the effect of inflammatory bowel disease (IBD) on the quality of life, we interviewed 43 patients with ulcerative colitis (UC) and 54 with Crohn's disease. Patients identified frequent and important problems in five areas. Primary bowel symptoms, systemic symptoms, and altered emotional function were common; functional and social …

Maternal psychiatric disorders in pediatric inflammatory bowel disease and cystic fibrosis

Publication Year: 1994 Source: Child Psychiatry Hum Dev PMID: 7805435 DOI: 10.1007/BF02251099

Inflammatory bowel disease (IBD) is one of the most common causes of chronic vomiting and diarrhea in cats. A definitive diagnosis is made only by biopsy. This article presents an overview of differential diagnosis of IBD in cats. Treatment of this syndrome is reviewed in detail. A great majority of …

Affected sib pair identity by state analyses

Publication Year: 1994 Source: Genet Epidemiol PMID: 7813897 DOI: 10.1002/gepi.1370110405

Comment on Gut. 2011 Jun;60(6):780-7. Antibodies that target tumor necrosis factor are effective at inducing and maintaining remission in both Crohn's disease (infliximab, adalimumab and certolizumab) and ulcerative colitis (infliximab). The results of a randomized controlled trial of adalimumab for inducing remission in moderately to severely active ulcerative colitis have …

Vaccination of commercial layer chicks against infectious bursal disease with maternally derived antibodies

Publication Year: 1994 Source: Vet Rec PMID: 7817504 DOI: 10.1136/vr.135.12.273

To investigate the possibilities of differentiating between inflammatory bowel disease (IBD) and infectious colitis on histologic grounds, a prospective histologic study of 105 patients with a first attack of colitis was undertaken. Rectal biopsies were performed on four occasions during 1 year. The strongest predictor of IBD was basal plasmacytosis, …

Increase of circulating gamma/delta T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease

Publication Year: 1994 Source: Clin Exp Immunol PMID: 7923890 DOI: 10.1111/j.1365-2249.1994.tb06611.x

Curcumin (diferulolylmethane) is an anti-inflammatory phenolic compound found effective in preclinical models of inflammatory bowel diseases (IBD) and in ulcerative colitis patients. Pharmacokinetics of curcumin and its poor systemic bioavailability suggest that it targets preferentially intestinal epithelial cells. The intestinal epithelium, an essential component of the gut innate defense mechanisms, …

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