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Familial aggregation of inflammatory bowel disease in northern Italy: a multicenter study. The Gruppo di Studio per le Malattie Infiammatorie Intestinali (IBD Study Group)
Publication Year: 1992 Source: Gastroenterology PMID: 1634069 DOI: 10.1016/0016-5085(92)90841-l
Azathioprine and 6-mercaptopurine are widely used in the management of inflammatory bowel disease (IBD). However, approximately 25% of IBD patients experience toxicity, and up to 10% show resistance to these thiopurine drugs. The importance of genetic variability in determining thiopurine toxicity was first recognized over 25 years ago with the …
Drug therapy for inflammatory bowel disease: Part II
Publication Year: 1992 Source: Am J Surg PMID: 1636900 DOI: 10.1016/s0002-9610(05)80381-2
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Mucosal cell-mediated immunity to mycobacterial, enterobacterial and other microbial antigens in inflammatory bowel disease
Publication Year: 1992 Source: Clin Exp Immunol PMID: 1735186 DOI: 10.1111/j.1365-2249.1992.tb02979.x
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PEDSCORE analysis of identical by descent (IBD) marker allele distributions among family members with cutaneous melanoma
Publication Year: 1992 Source: Cytogenet Cell Genet PMID: 1737511 DOI: 10.1159/000133256
BACKGROUND: Recent advances have been made in the care of children with inflammatory bowel disease (IBD). We aimed to describe trends in medication use, associated health services, and outcomes (hospitalization and surgical rates) between 1994-2007 in children with IBD. METHODS: Children <18 years diagnosed 1994-2004 with IBD living in Ontario …
The cost benefit of vaccinating broiler flocks against subclinical infectious bursal disease
Publication Year: 1992 Source: Avian Pathol PMID: 18670916 DOI: 10.1080/03079459208418819
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Pathogenesis of infectious bursal disease in cyclophosphamide-treated chickens
Publication Year: 1992 Source: Avian Pathol PMID: 18670979 DOI: 10.1080/03079459208418882
BACKGROUND: There has been little investigation of fatigue, a common symptom in inflammatory bowel disease (IBD). The aim of this study was to evaluate fatigue more comprehensively, considering relationships with psychological and biological factors simultaneously in a population-based IBD community sample. METHODS: Manitoba IBD Cohort Study participants (n = 318; …
Acute infectious bursal disease in poultry: Isolation and characterisation of a highly virulent strain
Publication Year: 1991 Source: Avian Pathol PMID: 18680006 DOI: 10.1080/03079459108418748
BACKGROUND: The IBD5 locus (OMIM ID 606348) on chromosome 5 was suggested to be one of the most important genetic factors involved in the pathogenesis of inflammatory bowel diseases (IBDs). However the main contributor from this region is still unknown. METHODS: We investigated the possible association of the IBD5 locus …
Double-antibody sandwich ELISA for detection of infectious bursal disease virus
Publication Year: 1991 Source: Br Vet J PMID: 1652348 DOI: 10.1016/0007-1935(91)90049-S
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Inflammatory mediators in cotton-top tamarins (CTT) with acute and chronic colitis
Publication Year: 1991 Source: Agents Actions PMID: 1665291 DOI: 10.1007/BF01993271
IgG subclass-containing cells in colonic mucosa were examined in three groups; 1) normal controls 2) cases of ulcerative colitis (UC) 3) cases of colitis excluding UC and Crohn's disease (non-IBD colitis) by indirect immunoperoxidase staining method using mouse anti-IgG subclass monoclonal antibodies. The numbers (and proportions) of IgG1, IgG2, IgG3, …
Azathioprine reduces extravasation and neutrophil trafficking in immune complex-mediated inflammation in the rat colon
Publication Year: 1991 Source: Agents Actions PMID: 1665297 DOI: 10.1007/BF01993293
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