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The Mechanism of "Treating Different Diseases with the Same Treatment" by Qiangji Jianpi Decoction in Ankylosing Spondylitis Combined with Inflammatory Bowel Disease: A Comprehensive Analysis of Multiple Methods
Publication Year: 2024 Source: Gastroenterol Res Pract PMID: 38808131 DOI: 10.1155/2024/9709260
BACKGROUND: Ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) are prevalent autoimmune disorders that often co-occur, posing significant treatment challenges. This investigation adopts a multidisciplinary strategy, integrating bioinformatics, network pharmacology, molecular docking, and Mendelian randomization, to elucidate the relationship between AS and IBD and to investigate the potential mechanisms of …
Silencing ANGPT2 alleviates ulcerative colitis by regulating autophagy-mediated NLRP3 inflammasome inactivation via the mTOR signaling pathway
Publication Year: 2024 Source: Braz J Med Biol Res PMID: 38808888
No Abstract
Highly Effective Nobiletin-MPN in Yeast Microcapsules for Targeted Modulation of Oxidative Stress, NLRP3 Inflammasome Activation, and Immune Responses in Ulcerative Colitis
Publication Year: 2024 Source: J Agric Food Chem PMID: 38809142 DOI: 10.1021/acs.jafc.3c09530
Inflammatory bowel disease (IBD) etiology is intricately linked to oxidative stress and inflammasome activation. Natural antioxidant nobiletin (NOB) contains excellent anti-inflammatory properties in alleviating intestinal injury. However, the insufficient water solubility and low bioavailability restrict its oral intervention for IBD. Herein, we constructed a highly efficient NOB-loaded yeast microcapsule (YM, …
Increased Active Inflammation in the Colon is Not a Reliable Predictor of an Elevated Risk of Dysplasia in Patients With Primary Sclerosing Cholangitis and Ulcerative Colitis
Publication Year: 2024 Source: Am J Surg Pathol PMID: 38809303
No Abstract
Correction: Linking bacterial enterotoxins and alpha defensin 5 expansion in the Crohn's colitis: A new insight into the etiopathogenetic and differentiation triggers driving colonic inflammatory bowel disease
Publication Year: 2024 Source: PLoS One PMID: 38809824
No Abstract
Inflammatory Bowel Disease in Cytoreductive Surgery and Heated Intraperitoneal Chemotherapy
Publication Year: 2024 Source: Am Surg PMID: 38810100 DOI: 10.1177/00031348241257471
BACKGROUND: Inflammatory bowel diseases (IBDs) pose an increased risk of gastrointestinal cancer with especially worse prognosis. Cytoreductive surgery and heated intraperitoneal chemotherapy (CRS/HIPEC) improves outcomes in selected patients with colorectal peritoneal metastases. Little published data describes the outcomes of CRS/HIPEC in IBD patients. METHODS: We performed a retrospective review of …
Alcohol inducing macrophage M2b polarization in colitis by modulating the TRPV1-MAPK/NF-κB pathways
Publication Year: 2024 Source: Phytomedicine PMID: 38810558 DOI: 10.1016/j.phymed.2024.155580
BACKGROUND: Macrophages exhibit different phenotypes in inflammatory bowel disease (IBD) and promote inflammation or tissue repair depending on their polarization state. Alcohol is a widely used solvent in pharmaceutical formulations, and its consumption is associated with an increased risk of colitis; however, its effects on macrophages in IBD remain poorly …
Influence of climate extremes on long-term changes in cyanobacterial blooms in a eutrophic and shallow lake
Publication Year: 2024 Source: Sci Total Environ PMID: 38810759 DOI: 10.1016/j.scitotenv.2024.173601
Climate change and human activities have crucial effects on the variations in phytoplankton blooms in lakes worldwide. A record-breaking heatwave and drought event was reported in the middle and lower reaches of the Yangtze River during the summer of 2022, but only little is known about how cyanobacterial blooms in …
Non-invasive evaluation of mucosal healing by intestinal ultrasound or fecal calprotectin is efficient in Crohn's disease: A cross-sectional study
Publication Year: 2024 Source: Clin Res Hepatol Gastroenterol PMID: 38810879
No Abstract
The Pouch Corner: A Review of Functional Pouch Disorders
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38811018
No Abstract
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