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Animal models of inflammatory bowel disease: a review
Publication Year: 2014 Source: Inflammopharmacology PMID: 24906689 DOI: 10.1007/s10787-014-0207-y
Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are the major diseases of the lower gastrointestinal tract. The intestinal epithelium plays a critical role in the host's interactions with the large communities of resident luminal bacteria. Epithelial cells recognize the bacterial components via pattern-recognition receptors. Toll-like receptors (TLRs) are a …
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