ID：S11
Therapeutic Strategy：Improveming Intestinal Microecology
Synonyms：the intestinal microbiota
Related Targets：Bacteroides; Eubacteria; Lactobacilli
Related Drugs：antibiotics; probiotics; prebiotics; postbiotics; synbiotics; fecal microbiota transplantation (FMT)
Mechanism：The imbalance between beneficial bacteria and harmful pathogenic bacteria in patients can trigger abnormal immune response in genetically susceptible people . Meanwhile, the inflammatory cells and factors can cause the intestinal mucosa injury. In IBD patients, the biodiversity of intestinal microbiota was decreased, with the most pronounced changes in the number of normal anaerobic bacteria such as Bacteroides, Eubacteria and Lactobacilli. Mucosal inflammation in IBD has been proved associated with the loss of these normal anaerobic bacteria

Related Literature

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🔗 DOI: 10.1136/gut.2003.025403
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📅 Publication Date: 2019-12-25
📖 Source: Clin Transl Med
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