| Target ID: | Tar10 |
|---|---|
| ID: | T63414 |
| Target Name: | P2X purinoceptor 7 (P2RX7) |
| Target Type: | Protein |
| CID: | 11547499 |
| URL: | https://db.idrblab.net/ttd/data/target/details/T63414 |
| Related Drugs: | -- |
Knowledge Graph
Flavokawain B inhibits NF-κB inflammatory signaling pathway activation in infla…
PMID: 38583725
Year: 2024
Relationship Type:
Mechanism Investigation
Score: 5.2
Inflammatory bowel disease (IBD) is characterized by recurrent inflammatory reactions in the intestinal mucosa, including ulcerative colitis (UC) and…
Direct inhibition of the TXNIP-NLRP3-GSDMD pathway reduces pyroptosis in colono…
PMID: 40195510
Year: 2025
Relationship Type:
Mechanism Investigation
Score: 5.0
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. The etiology of UC is multifaceted, and the underlying pathogenesis remains incomple…
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio44684 | CHEMBL3989951 | Small molecule | NAVOXIMOD | 316.38 | C18H21FN2O2 | NEUTRAL | Details |
| bio44685 | CHEMBL4297213 | Protein | AFAMELANOTIDE ACETATE | 1706.93 | C80H115N21O21 | -- | Details |
| bio44686 | CHEMBL1753 | Small molecule | CLINDAMYCIN | 424.99 | C18H33ClN2O5S | NEUTRAL | Details |
| bio44687 | CHEMBL1201832 | Protein | ROMIPLOSTIM | -- | -- | -- | Details |
| bio44688 | CHEMBL837 | Small molecule | 7-ETHYL-10-HYDROXYCAMPTOTHECIN | 392.41 | C22H20N2O5 | NEUTRAL | Details |
| bio44689 | CHEMBL5314393 | Small molecule | LY2624803 | 379.46 | C22H25N3O3 | ACID | Details |
| bio44690 | CHEMBL8145 | Small molecule | DAIDZEIN | 254.24 | C15H10O4 | ACID | Details |
| bio44691 | CHEMBL86882 | Small molecule | ETILEFRINE | 181.24 | C10H15NO2 | BASE | Details |
| bio44692 | CHEMBL1230575 | Small molecule | MENAQUINONE 7 | 649.02 | C46H64O2 | NEUTRAL | Details |
| bio44693 | CHEMBL3527416 | Small molecule | MONOXERUTIN | 654.57 | C29H34O17 | NEUTRAL | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||