| Target ID: | Tar11 |
|---|---|
| ID: | T23673 |
| Target Name: | Proto-oncogene c-RAF (c-RAF) |
| Target Type: | Protein |
| CID: | -- |
| URL: | https://db.idrblab.net/ttd/data/target/details/T23673 |
| Related Drugs: | -- |
Knowledge Graph
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
Flavokawain B inhibits NF-κB inflammatory signaling pathway activation in infla…
PMID: 38583725
Year: 2024
Relationship Type:
Mechanism Investigation
Score: 5.2
Inflammatory bowel disease (IBD) is characterized by recurrent inflammatory reactions in the intestinal mucosa, including ulcerative colitis (UC) and…
Direct inhibition of the TXNIP-NLRP3-GSDMD pathway reduces pyroptosis in colono…
PMID: 40195510
Year: 2025
Relationship Type:
Mechanism Investigation
Score: 5.0
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. The etiology of UC is multifaceted, and the underlying pathogenesis remains incomple…
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio8 | CHEMBL46917 | Small molecule | CARBARIL | 201.22 | C12H11NO2 | NEUTRAL | Details |
| bio9 | CHEMBL298359 | Small molecule | MITOMYCIN A | 349.34 | C16H19N3O6 | NEUTRAL | Details |
| bio10 | CHEMBL2108481 | Unknown | ANCROD | -- | -- | -- | Details |
| bio11 | CHEMBL4650463 | Small molecule | DEUTARSERINE | 106.1 | C3H7NO3 | ZWITTERION | Details |
| bio12 | CHEMBL3039531 | Small molecule | DANIRIXIN | 441.91 | C19H21ClFN3O4S | ACID | Details |
| bio13 | CHEMBL1185 | Small molecule | ZOLMITRIPTAN | 287.36 | C16H21N3O2 | BASE | Details |
| bio14 | CHEMBL3039594 | Small molecule | GENTAMICIN SULFATE | 1488.81 | C60H125N15O25S | -- | Details |
| bio15 | CHEMBL2109321 | Antibody | CAROTUXIMAB | -- | -- | -- | Details |
| bio16 | CHEMBL1201832 | Protein | ROMIPLOSTIM | -- | -- | -- | Details |
| bio17 | CHEMBL2107881 | Protein | REGRAMOSTIM | -- | -- | -- | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||