Target ID:Tar14
ID:T97353
Target Name:Integrin alpha-2/beta-1 (ITGA2/B1)
Target Type:Protein
CID:--
URL:https://db.idrblab.net/ttd/data/target/details/T97353
Related Drugs:--

Knowledge Graph

Drug IDDrug NameTypeDrugBank IDTargetsCategoryLatest Progress
No data available

Flavokawain B inhibits NF-κB inflammatory signaling pathway activation in infla…

PMID: 38583725
Year: 2024
Relationship Type: Mechanism Investigation Score: 5.2

Inflammatory bowel disease (IBD) is characterized by recurrent inflammatory reactions in the intestinal mucosa, including ulcerative colitis (UC) and…

Direct inhibition of the TXNIP-NLRP3-GSDMD pathway reduces pyroptosis in colono…

PMID: 40195510
Year: 2025
Relationship Type: Mechanism Investigation Score: 5.0

Ulcerative colitis (UC) is a chronic inflammatory bowel disease. The etiology of UC is multifaceted, and the underlying pathogenesis remains incomple…

Evaluation of inflammatory bowel disease activity in children using serum trefo…

PMID: 32120375
Year: 2020
Relationship Type: Mechanism Investigation Score: 5.0

Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a class of severe and chronic diseases of the gastr…

Candidate IDSource IDSource TypeCompound TypeCandidate NameInclusion Criteria
No data available

Compound IDSource IDSource TypeCompound NameMolecular WeightMolecular FormulaMolecular Species
bio17913 CHEMBL730 Small molecule NITROGLYCERIN 227.08 C3H5N3O9 NEUTRAL Details
bio17914 CHEMBL878 Small molecule METOLAZONE 365.84 C16H16ClN3O3S NEUTRAL Details
bio17915 CHEMBL1079604 Small molecule METAXALONE 221.26 C12H15NO3 NEUTRAL Details
bio17916 CHEMBL1200399 Small molecule BUSPIRONE HYDROCHLORIDE 421.97 C21H32ClN5O2 NEUTRAL Details
bio17917 CHEMBL1200436 Small molecule OXANDROLONE 306.45 C19H30O3 NEUTRAL Details
bio17918 CHEMBL5095183 Small molecule IMLUNESTRANT 524.51 C29H24F4N2O3 NEUTRAL Details
bio17919 CHEMBL1200332 Small molecule PROTRIPTYLINE HYDROCHLORIDE 299.85 C19H22ClN BASE Details
bio17920 CHEMBL3707377 Small molecule SEGESTERONE ACETATE 370.49 C23H30O4 NEUTRAL Details
bio17921 CHEMBL5314602 Small molecule HYPERICIN SODIUM 526.43 C30H15NaO8 NEUTRAL Details
bio17922 CHEMBL603 Small molecule ZAFIRLUKAST 575.69 C31H33N3O6S ACID Details

Strategy IDTherapy StrategySynonymsRelated DrugsMechanism
No data available