| Target ID: | Tar2 |
|---|---|
| ID: | T77400 |
| Target Name: | Phosphodiesterase 2A (PDE2A) |
| Target Type: | Protein |
| CID: | -- |
| URL: | https://db.idrblab.net/ttd/data/target/details/T77400 |
| Related Drugs: | -- |
Knowledge Graph
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
Flavokawain B inhibits NF-κB inflammatory signaling pathway activation in infla…
PMID: 38583725
Year: 2024
Relationship Type:
Mechanism Investigation
Score: 5.2
Inflammatory bowel disease (IBD) is characterized by recurrent inflammatory reactions in the intestinal mucosa, including ulcerative colitis (UC) and…
Direct inhibition of the TXNIP-NLRP3-GSDMD pathway reduces pyroptosis in colono…
PMID: 40195510
Year: 2025
Relationship Type:
Mechanism Investigation
Score: 5.0
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. The etiology of UC is multifaceted, and the underlying pathogenesis remains incomple…
Evaluation of inflammatory bowel disease activity in children using serum trefo…
PMID: 32120375
Year: 2020
Relationship Type:
Mechanism Investigation
Score: 5.0
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a class of severe and chronic diseases of the gastr…
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio35831 | CHEMBL3989968 | Small molecule | DIFAMILAST | 446.45 | C23H24F2N2O5 | NEUTRAL | Details |
| bio35832 | CHEMBL514800 | Small molecule | APREMILAST | 460.51 | C22H24N2O7S | NEUTRAL | Details |
| bio35833 | CHEMBL4541964 | Small molecule | ZATOLMILAST | 405.8 | C21H15ClF3NO2 | ACID | Details |
| bio35834 | CHEMBL3770459 | Small molecule | LENRISPODUN PHOSPHATE | 605.57 | C29H29FN7O5P | NEUTRAL | Details |
| bio35835 | CHEMBL332750 | Small molecule | TETOMILAST | 370.43 | C19H18N2O4S | ACID | Details |
| bio35836 | CHEMBL1339 | Small molecule | VARDENAFIL HYDROCHLORIDE | 525.08 | C23H33ClN6O4S | NEUTRAL | Details |
| bio35837 | CHEMBL4297460 | Small molecule | DOVRAMILAST | 472.56 | C24H28N2O6S | NEUTRAL | Details |
| bio35838 | CHEMBL1922282 | Small molecule | LIRIMILAST | 443.26 | C17H12Cl2N2O6S | NEUTRAL | Details |
| bio35839 | CHEMBL4568146 | Small molecule | ELBIMILAST | 443.27 | C21H13Cl2FN4O2 | NEUTRAL | Details |
| bio35840 | CHEMBL53538 | Small molecule | LODENAFIL | 504.61 | C23H32N6O5S | NEUTRAL | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||