| Target ID: | Tar3 |
|---|---|
| ID: | T53764 |
| Target Name: | Prolyl endopeptidase FAP (FAP) |
| Target Type: | Protein |
| CID: | -- |
| URL: | https://db.idrblab.net/ttd/data/target/details/T53764 |
| Related Drugs: | -- |
Knowledge Graph
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine…
PMID: 21208525
Year: 2010
Relationship Type:
Mechanism Investigation
Score: 6.8
Sulfasalazine salicylazosulfapyridine (SASP), consisting of 5-aminosalicylic acid bound to sulfapyridine by a diazo bond, is an effective drug in th…
CORM-3 alleviates the intestinal injury in a rodent model of hemorrhage shock a…
PMID: 37335421
Year: 2023
Relationship Type:
Mechanism Investigation
Score: 6.3
Hemorrhagic shock and resuscitation (HSR) can induce severe intestinal damages, thereby leading to sepsis and long-term complications including dysba…
Stable and scalable SERS tags conjugated with neutravidin for the detection of …
PMID: 33831854
Year: 2021
Relationship Type:
Target Validation
Score: 5.3
SERS tags are a class of nanoparticles with great potential in advanced imaging experiments. The preparation of SERS tags however is complex, as they…
Flavokawain B inhibits NF-κB inflammatory signaling pathway activation in infla…
PMID: 38583725
Year: 2024
Relationship Type:
Mechanism Investigation
Score: 5.2
Inflammatory bowel disease (IBD) is characterized by recurrent inflammatory reactions in the intestinal mucosa, including ulcerative colitis (UC) and…
Direct inhibition of the TXNIP-NLRP3-GSDMD pathway reduces pyroptosis in colono…
PMID: 40195510
Year: 2025
Relationship Type:
Mechanism Investigation
Score: 5.0
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. The etiology of UC is multifaceted, and the underlying pathogenesis remains incomple…
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio4171 | CHEMBL2103772 | Small molecule | RACECADOTRIL | 385.49 | C21H23NO4S | NEUTRAL | Details |
| bio4172 | CHEMBL3115298 | Small molecule | IZILENDUSTAT | 433.94 | C22H28ClN3O4 | NEUTRAL | Details |
| bio4173 | CHEMBL325695 | Small molecule | FASIDOTRIL | 443.52 | C23H25NO6S | NEUTRAL | Details |
| bio4174 | CHEMBL4650417 | Enzyme | PROLYL ENDOPEPTIDASE | -- | -- | -- | Details |
| bio4175 | CHEMBL1697842 | Small molecule | METHALLENESTRIL | 286.37 | C18H22O3 | ACID | Details |
| bio4176 | CHEMBL107747 | Small molecule | GEMOPATRILAT | 378.49 | C19H26N2O4S | ACID | Details |
| bio4177 | CHEMBL1516410 | Small molecule | ECADOTRIL | 385.49 | C21H23NO4S | NEUTRAL | Details |
| bio4178 | CHEMBL42583 | Small molecule | SAMPATRILAT | 584.69 | C26H40N4O9S | ZWITTERION | Details |
| bio4179 | CHEMBL35084 | Small molecule | CANDOXATRIL | 515.65 | C29H41NO7 | ACID | Details |
| bio4180 | CHEMBL289556 | Small molecule | OMAPATRILAT | 408.55 | C19H24N2O4S2 | ACID | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||