| Target ID: | Tar5 |
|---|---|
| ID: | T30635 |
| Target Name: | C-X-C motif chemokine 10 (CXCL10) |
| Target Type: | Protein |
| CID: | 1549008 |
| URL: | https://db.idrblab.net/ttd/data/target/details/T30635 |
| Related Drugs: | -- |
Knowledge Graph
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| Drug81 | Terbinafine | Chemical drug | DB00857 | -- | -- | Under clinical trials | Details |
Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting …
PMID: 36892981
Year: 2023
Relationship Type:
Mechanism Investigation
Score: 5.8
OBJECTIVE: Ulcerative colitis (UC) is a relapsing inflammatory health state posing significant worldwide problems. Ezetimibe is a cholesterol-lowerin…
A novel function of CXCL10 in mediating monocyte production of proinflammatory …
PMID: 28899907
Year: 2017
Relationship Type:
Mechanism Investigation
Score: 5.8
IFN-gamma-inducible protein 10 (CXCL10), a chemokine that is abundantly secreted in response to inflammatory stimuli, has been implicated in the path…
Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a…
PMID: 26892362
Year: 2016
Relationship Type:
Mechanism Investigation
Score: 5.8
Progranulin (PGRN), a pleiotrophic growth factor, is known to play an important role in the maintenance and regulation of the homeostatic dynamics of…
The protective role of 3-Indoleglyoxylic acid in Bisphenol S-induced intestinal…
PMID: 40279686
Year: 2025
Relationship Type:
Mechanism Investigation
Score: 5.3
Bisphenol S (BPS) has become extensively used in the manufacturing of consumer products. BPS mainly enters the body through food and water, with oral…
CXCL10 as a shared specific marker in rheumatoid arthritis and inflammatory bow…
PMID: 37328529
Year: 2023
Relationship Type:
Mechanism Investigation
Score: 5.3
This study aimed to identify shared specific genes associated with rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) through bioinformat…
Flavokawain B inhibits NF-κB inflammatory signaling pathway activation in infla…
PMID: 38583725
Year: 2024
Relationship Type:
Mechanism Investigation
Score: 5.2
Inflammatory bowel disease (IBD) is characterized by recurrent inflammatory reactions in the intestinal mucosa, including ulcerative colitis (UC) and…
Direct inhibition of the TXNIP-NLRP3-GSDMD pathway reduces pyroptosis in colono…
PMID: 40195510
Year: 2025
Relationship Type:
Mechanism Investigation
Score: 5.0
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. The etiology of UC is multifaceted, and the underlying pathogenesis remains incomple…
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio42183 | CHEMBL730 | Small molecule | NITROGLYCERIN | 227.08 | C3H5N3O9 | NEUTRAL | Details |
| bio42184 | CHEMBL1200332 | Small molecule | PROTRIPTYLINE HYDROCHLORIDE | 299.85 | C19H22ClN | BASE | Details |
| bio42185 | CHEMBL1200348 | Small molecule | SULCONAZOLE NITRATE | 460.77 | C18H16Cl3N3O3S | NEUTRAL | Details |
| bio42186 | CHEMBL3987016 | Small molecule | MIVEBRESIB | 459.47 | C22H19F2N3O4S | NEUTRAL | Details |
| bio42187 | CHEMBL495 | Small molecule | ALPROSTADIL | 354.49 | C20H34O5 | ACID | Details |
| bio42188 | CHEMBL46917 | Small molecule | CARBARIL | 201.22 | C12H11NO2 | NEUTRAL | Details |
| bio42189 | CHEMBL298359 | Small molecule | MITOMYCIN A | 349.34 | C16H19N3O6 | NEUTRAL | Details |
| bio42190 | CHEMBL4297310 | Small molecule | DORDAVIPRONE | 386.5 | C24H26N4O | NEUTRAL | Details |
| bio42191 | CHEMBL2108481 | Unknown | ANCROD | -- | -- | -- | Details |
| bio42192 | CHEMBL4650463 | Small molecule | DEUTARSERINE | 106.1 | C3H7NO3 | ZWITTERION | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||