| Target ID: | Tar77 |
|---|---|
| ID: | Q5VWK5 |
| Target Name: | Interleukin-23 receptor (IL-23 receptor) (IL-23R) |
| Target Type: | Protein |
| CID: | -- |
| URL: | https://www.uniprot.org/uniprotkb/Q5VWK5 |
| Related Drugs: | -- |
Knowledge Graph
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
Targeting the IL-23 Receptor Gene: A Promising Approach in Inflammatory Bowel D…
PMID: 40429917
Year: 2025
Relationship Type:
Mechanism Investigation
Score: 7.3
Inflammatory bowel disease (IBD), which includes Crohn's Disease (CD) and ulcerative colitis (UC), is characterized by chronic inflammation of the ga…
IL-23 receptor regulation by Let-7f in human CD4+ memory T cells
PMID: 21508257
Year: 2011
Relationship Type:
Mechanism Investigation
Score: 5.0
CD4(+) memory T cells include the Th17 cell population, which has been shown to be implicated in autoimmune and inflammatory diseases. These memory T…
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease
PMID: 17309073
Year: 2007
Relationship Type:
Mechanism Investigation
Score: 5.0
Nitric oxide (.NO) generation from conversion of l-arginine to citrulline by nitric oxide synthase isoforms plays a critical role in vascular homeos…
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio195300 | CHEMBL3975522 | Small molecule | EBOPIPRANT | 599.75 | C30H34FN3O5S2 | NEUTRAL | Details |
| bio195301 | CHEMBL603 | Small molecule | ZAFIRLUKAST | 575.69 | C31H33N3O6S | ACID | Details |
| bio195302 | CHEMBL407 | Small molecule | FLUMAZENIL | 303.29 | C15H14FN3O3 | NEUTRAL | Details |
| bio195303 | CHEMBL1742408 | Small molecule | OSEMOZOTAN | 343.38 | C19H21NO5 | BASE | Details |
| bio195304 | CHEMBL29741 | Small molecule | IRAMPANEL | 309.37 | C18H19N3O2 | BASE | Details |
| bio195305 | CHEMBL93747 | Small molecule | NETOGLITAZONE | 381.43 | C21H16FNO3S | NEUTRAL | Details |
| bio195306 | CHEMBL1950554 | Small molecule | BINODENOSON | 391.43 | C17H25N7O4 | NEUTRAL | Details |
| bio195307 | CHEMBL3544908 | Small molecule | AZATADINE MALEATE | 522.55 | C28H30N2O8 | NEUTRAL | Details |
| bio195308 | CHEMBL2109287 | Antibody drug conjugate | TECHNETIUM TC 99M NOFETUMOMAB MERPENTAN | -- | -- | -- | Details |
| bio195309 | CHEMBL1761 | Small molecule | PROCYCLIDINE HYDROCHLORIDE | 323.91 | C19H30ClNO | BASE | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||