| Target ID: | Tar92 |
|---|---|
| ID: | Q9NZH6 |
| Target Name: | Interleukin-37 (IL-37) (FIL1 zeta) (IL-1X) (Interleukin-1 family member 7) (IL-1F7) (Interleukin-1 homolog 4) (IL-1H) (IL-1H4) (Interleukin-1 zeta) (IL-1 zeta) (Interleukin-1-related protein) (IL-1RP1) |
| Target Type: | Protein |
| CID: | -- |
| URL: | https://www.uniprot.org/uniprotkb/Q9NZH6 |
| Related Drugs: | -- |
Knowledge Graph
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
IL-37 As a Potential Biotherapeutics of Inflammatory Diseases
PMID: 32348214
Year: 2020
Relationship Type:
Mechanism Investigation
Score: 6.8
Interleukin-37 (IL-37) was discovered as a new member of pro-inflammatory IL-1 superfamily. However, further studies suggested that IL-37 plays a cri…
IL-37d Negatively Regulates NLRP3 Transcription via Receptor-mediated Pathway a…
PMID: 32582954
Year: 2021
Relationship Type:
Mechanism Investigation
Score: 6.3
BACKGROUND: Interleukin-37 (IL-37) is a new negative immune regulator. It has 5 splicing forms, IL-37a-e, and most research mainly focuses on IL-37b …
The role of IL-37 in gastrointestinal diseases
PMID: 39206201
Year: 2024
Relationship Type:
Therapeutic Applications
Score: 5.3
Gastrointestinal mucosal surface is frequently under challenge due to it's the large surface area and most common entry of microbes. IL-37, an anti-i…
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio85031 | CHEMBL4650250 | Protein | EFMARODOCOKIN ALFA | -- | -- | -- | Details |
| bio85032 | CHEMBL2108469 | Protein | MUPLESTIM | -- | -- | -- | Details |
| bio85033 | CHEMBL2109037 | Protein | ILODECAKIN | -- | -- | -- | Details |
| bio85034 | CHEMBL5095282 | Protein | NEMVALEUKIN ALFA | -- | -- | -- | Details |
| bio85035 | CHEMBL39736 | Small molecule | BUFORMIN | 157.22 | C6H15N5 | BASE | Details |
| bio85036 | CHEMBL5095458 | Protein | REZPEGALDESLEUKIN | -- | -- | -- | Details |
| bio85037 | CHEMBL5314892 | Protein | VEVOCTADEKIN | -- | -- | -- | Details |
| bio85038 | CHEMBL3990018 | Antibody drug conjugate | CERGUTUZUMAB AMUNALEUKIN | -- | -- | -- | Details |
| bio85039 | CHEMBL4297771 | Unknown | INTERLEUKIN-10 | -- | -- | -- | Details |
| bio85040 | CHEMBL5095376 | Protein | MELREDABLEUKIN ALFA | -- | -- | -- | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||