|
IcsP (SopA)
|
icsP/sopA
|
0.0001003 |
2 |
VF0122
|
Exoenzyme |
(icsP/sopA) outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA [IcsP (SopA) (VF0122) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
Ata
|
ata
|
0.6548837 |
6,085 |
VF1333
|
Adherence |
(ata) trimeric autotransporter adhesin Ata [Ata (VF1333) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
Alpha-hemolysin
|
hly/hla
|
0.0001003 |
2 |
VF0001
|
Exotoxin |
(hly/hla) Alpha-Hemolysin precursor [Alpha-hemolysin (VF0001) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
TFP
|
ACICU_RS16840
|
27.7250802 |
19,944 |
VF1334
|
Adherence |
(pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
IcsA (VirG)
|
icsA/virG
|
0.0000501 |
1 |
VF0121
|
Motility |
(icsA/virG) autotransporter, actin tail assembly protein IcsA/VirG [IcsA (VirG) (VF0121) - Motility (VFC0204)] [Shigella flexneri 2a str. 301]
|
|
Rvh T4SS
|
virB6-3
|
0.0000501 |
1 |
VF0487
|
Effector delivery system |
(virB6-3) type IV secretion system protein VirB6 family [Rvh T4SS (VF0487) - Effector delivery system (VFC0086)] [Anaplasma phagocytophilum HZ]
|
|
LPS
|
gtrB
|
0.0003008 |
6 |
VF0124
|
Immune modulation |
(gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cap8F
|
0.1620036 |
3,100 |
VF0003
|
Immune modulation |
(cap8J) type 8 capsular polysaccharide synthesis protein Cap8J [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Aerobactin
|
iucB
|
0.0003008 |
4 |
VF0123
|
Nutritional/Metabolic factor |
(iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301]
|
|
Hyaluronic acid capsule
|
hasC
|
0.0001504 |
3 |
VF0244
|
Immune modulation |
(hasC) UTP--glucose-1-phosphate uridylyltransferase HasC [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
Beta-hemolysin
|
hlb
|
0.0000501 |
1 |
VF0002
|
Exotoxin |
(hlb) beta-hemolysin [Beta-hemolysin (VF0002) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus COL]
|
|
CNA
|
cna
|
0.000351 |
7 |
VF0005
|
Adherence |
(cna) collagen adhesin precursor [CNA (VF0005) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
T6SS
|
tssK
|
12.807862 |
19,868 |
VF1337
|
Effector delivery system |
(hcp/tssD) type VI secretion system tube protein Hcp [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
TCP
|
tcpI
|
0.0000501 |
1 |
VF0126
|
Adherence |
(tcpI) negative regulator of the major pilin TcpA [TCP (VF0126) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
LPS
|
acpXL
|
0.000702 |
14 |
VF0367
|
Immune modulation |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
T6SS secreted effectors
|
tse4
|
0.0840353 |
1,399 |
VF1338
|
Effector delivery system |
(tse3) T6SS effector Tse3, unknown function [T6SS secreted effectors (VF1338) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ATCC 17978]
|
|
Clumping factor
|
clfA
|
0.0006518 |
12 |
VF0004
|
Adherence |
(clfB) Clumping factor B, adhesin [Clumping factor (VF0004) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
T2SS
|
gspD
|
12.8385479 |
19,944 |
VF1335
|
Effector delivery system |
(gspN) type II secretion system protein N [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
CpaA
|
cpaA
|
0.0827818 |
1,526 |
VF1336
|
Exoenzyme |
(cpaA) metalloendopeptidase CpaA [CpaA (VF1336) - Exoenzyme (VFC0251)] [Acinetobacter baumannii BJAB0715]
|
|
Staphopain
|
sspB
|
0.0004513 |
7 |
VF0006
|
Exoenzyme |
(sspB) staphopain cysteine proteinase SspB [Staphopain (VF0006) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Spes
|
speG
|
0.0000501 |
1 |
VF0248
|
Exotoxin |
(speG) streptococcal exotoxin G precursor [Spes (VF0248) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
EbpS
|
ebp
|
0.0002006 |
3 |
VF0008
|
Adherence |
(ebp) cell surface elastin binding protein [EbpS (VF0008) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
T6SS
|
vipB
|
0.0002006 |
2 |
VF0480
|
Effector delivery system |
(clpB) type VI secretion system ATPase ClpV1 [T6SS (VF0480) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
TraJ
|
AAA92657
|
0.0003008 |
6 |
VF0241
|
Invasion |
(AAA92657) unknown protein [TraJ (VF0241) - Invasion (VFC0083)] [Escherichia coli]
|
|
Capsule
|
cpsA/uppS
|
0.0002507 |
5 |
VF0361
|
Immune modulation |
(cpsI) UDP-galactopyranose mutase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
RtxA
|
rtxE
|
0.0000501 |
1 |
VF0482
|
Exotoxin |
(rtxE) RTX toxin transporter, ATPase protein [RtxA (VF0482) - Exotoxin (VFC0235)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
Esp
|
esp
|
0.0001003 |
2 |
VF0353
|
Adherence |
(esp) Enterococcal surface protein; Esp [Esp (VF0353) - Adherence (VFC0001)] [Enterococcus faecalis str. MMH594]
|
|
Pic
|
pic
|
0.0000501 |
1 |
VF0232
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0232) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
PhoPQ
|
phoP
|
0.0008022 |
16 |
VF0111
|
Regulation |
(phoP) response regulator in two-component regulatory system with PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
FbpA/Fbp68
|
fbpA/fbp68
|
0.0001003 |
2 |
VF0595
|
Adherence |
(fbpA/fbp68) fibronectin-binding protein FbpA [FbpA/Fbp68 (VF0595) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Lateral flagella
|
lfhA
|
0.0001504 |
3 |
VF0474
|
Motility |
(flgC) flagellar basal body rod protein FlgC [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
Polar flagella
|
nueA
|
0.003911 |
66 |
VF0473
|
Motility |
(flrA) FleQ protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
GroEL
|
groEL
|
0.0015544 |
31 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
AS
|
EF0485
|
0.0000501 |
1 |
VF0352
|
Adherence |
(EF0485) aggregation substance [AS (VF0352) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Fur
|
fur
|
0.0009527 |
19 |
VF0113
|
Regulation |
(fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuS
|
0.0001003 |
2 |
VF0234
|
Nutritional/Metabolic factor |
(chuA) Outer membrane heme/hemoglobin receptor ChuA [Chu (VF0234) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli O157:H7 str. EDL933]
|
|
RpoS
|
rpoS
|
0.0009025 |
17 |
VF0112
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Tap type IV pili
|
tapT
|
0.0000501 |
1 |
VF0475
|
Adherence |
(tapT) twitching ATPase [Tap type IV pili (VF0475) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
OmpA
|
ompA
|
0.0008022 |
15 |
VF0236
|
Invasion |
(ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Exe T2SS
|
exeI
|
0.0005515 |
9 |
VF0478
|
Effector delivery system |
(exeI) general secretion pathway protein I [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
|
|
Flagella
|
fliD
|
0.0014039 |
25 |
VF0114
|
Motility |
(motB) flagellar motor protein MotB [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
AslA
|
aslA
|
0.0001504 |
3 |
VF0238
|
Invasion |
(aslA) putative arylsulfatase [AslA (VF0238) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Hyaluronidase
|
EF3023
|
0.0001003 |
2 |
VF0359
|
Exoenzyme |
(EF3023) polysaccharide lyase, family 8 [Hyaluronidase (VF0359) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
|
|
Ibes
|
ibeC
|
0.0012535 |
22 |
VF0237
|
Invasion |
(ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS (SPI-1 encode)
|
hilA
|
0.0004513 |
6 |
VF0116
|
Effector delivery system |
(spaO/sctQ) type III secretion system C ring protein SpaO [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS
|
mxiA
|
0.0008022 |
6 |
VF0118
|
Effector delivery system |
(ipgE) type III secretion system chaperone for IpgD [TTSS (VF0118) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
K1 capsule
|
kpsD
|
0.0005014 |
9 |
VF0239
|
Invasion |
(kpsC) Capsule polysaccharide export protein [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
Phospholipase C
|
plc1
|
2.3167369 |
19,940 |
VF0470
|
Exotoxin |
(plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
Cwp84
|
cwp84
|
0.0001003 |
2 |
VF0590
|
Exoenzyme |
(cwp84) cell wall-binding cysteine protease Cwp84 [Cwp84 (VF0590) - Exoenzyme (VFC0251)] [Clostridium difficile 630]
|
|
PNAG
|
pgaB
|
3.0254713 |
19,894 |
VF0472
|
Biofilm |
(pgaD) poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Salmochelin siderophore
|
iroN
|
0.009627 |
188 |
VF0230
|
Nutritional/Metabolic factor |
(iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Quorom sensing
|
abaI
|
1.8769053 |
19,011 |
VF0471
|
Biofilm |
(abaI) N-acyl-L-homoserine lactone synthetase [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Capsule
|
cps4J
|
0.0012535 |
25 |
VF0144
|
Immune modulation |
(cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
PmrAB
|
pmrA
|
0.0005515 |
10 |
VF1355
|
Regulation |
(pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
V8 protease
|
sspA
|
0.0001003 |
2 |
VF0023
|
Exoenzyme |
(sspA) serine protease; V8 protease; glutamyl endopeptidase [V8 protease (VF0023) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
MARTX
|
rtxB
|
0.0003008 |
4 |
VF0265
|
Exotoxin |
(rtxA) RTX toxin RtxA [MARTX (VF0265) - Exotoxin (VFC0235)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
FHA
|
fhaB
|
0.0000501 |
1 |
VF0025
|
Adherence |
(fhaB) filamentous hemagglutinin/adhesin [FHA (VF0025) - Adherence (VFC0001)] [Bordetella pertussis Tohama I]
|
|
TTSS secreted effectors
|
espX5
|
0.0001003 |
1 |
VF1111
|
Effector delivery system |
(espX5) Type III secretion system effector EspX5 [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
Hyaluronidase
|
hysA
|
0.0000501 |
1 |
VF0146
|
Exoenzyme |
(hysA) hyaluronidase [Hyaluronidase (VF0146) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
Aureolysin
|
aur
|
0.0001003 |
2 |
VF0024
|
Exoenzyme |
(aur) zinc metalloproteinase aureolysin [Aureolysin (VF0024) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
HitABC
|
hitB
|
0.0000501 |
1 |
VF0268
|
Nutritional/Metabolic factor |
(hitB) iron ABC transporter permease [HitABC (VF0268) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
Mu-toxin
|
nagH
|
0.0000501 |
1 |
VF0389
|
Exoenzyme |
(nagH) hyaluronidase [Mu-toxin (VF0389) - Exoenzyme (VFC0251)] [Clostridium perfringens str. 13]
|
|
IgA1 protease
|
zmpC
|
0.0000501 |
1 |
VF0147
|
Immune modulation |
(zmpC) immunoglobulin A1 protease [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Cya
|
cyaB
|
0.0000501 |
1 |
VF0028
|
Exotoxin |
(cyaB) cyclolysin secretion ATP-binding protein [Cya (VF0028) - Exotoxin (VFC0235)] [Bordetella pertussis Tohama I]
|
|
HSI-3
|
PA2359
|
0.0004513 |
8 |
VF0944
|
Effector delivery system |
(PA2359) transcriptional regulator [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
HSI-2
|
PA1663
|
0.0002006 |
4 |
VF0943
|
Effector delivery system |
(PA1663) transcriptional regulator [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
TTSS effectors secreted via both systems
|
spvC
|
0.0000501 |
1 |
VF0948
|
Effector delivery system |
(spvC) type III secretion system effector SpvC, phosphothreonine lyase [TTSS effectors secreted via both systems (VF0948) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS-2 secreted effectors
|
steC
|
0.0001003 |
2 |
VF0947
|
Effector delivery system |
(spvB) type III secretion system effector SpvB, ADP-ribosylation activity [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS-1 secreted effectors
|
sopE2
|
0.0000501 |
1 |
VF0949
|
Effector delivery system |
(sopE2) type III secretion system effector SopE2, guanine nucleotide exchange factor [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS
|
sycT
|
0.0012535 |
2 |
VF0140
|
Effector delivery system |
(sycT) chaperone for YopT [TTSS (VF0140) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
CsrA
|
csrA
|
0.0018552 |
37 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS secreted effectors
|
espR1
|
0.0002006 |
4 |
VF1110
|
Effector delivery system |
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
RelA
|
relA
|
0.0000501 |
1 |
VF0260
|
Regulation |
(relA) GTP diphosphokinase [RelA (VF0260) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Staphylokinase
|
sak
|
0.0000501 |
1 |
VF0021
|
Exoenzyme |
(sak) Staphylokinase precursor [Staphylokinase (VF0021) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SE
|
selk
|
0.0002006 |
4 |
VF0020
|
Exotoxin |
(selk) staphylococcal enterotoxin K precursor [SE (VF0020) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
LetA/S
|
letA
|
0.0006518 |
12 |
VF0262
|
Regulation |
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HSI-3 T6SS secreted effectors
|
pldB/tle5b
|
0.0000501 |
1 |
VF1350
|
Effector delivery system |
(pldB/tle5b) phospholipase D [HSI-3 T6SS secreted effectors (VF1350) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Lipase
|
lip
|
0.0008022 |
9 |
VF0012
|
Exoenzyme |
(lip) triacylglycerol lipase precursor [Lipase (VF0012) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
YadA
|
yadA
|
0.0001003 |
1 |
VF0133
|
Effector delivery system |
(yadA) trimeric autotransporter adhesin YadA [YadA (VF0133) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Gamma-hemolysin
|
hlgC
|
0.0004513 |
7 |
VF0011
|
Exotoxin |
(hlgA) gamma-hemolysin chain II precursor [Gamma-hemolysin (VF0011) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Isocitrate lyase
|
icl
|
0.0006017 |
11 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Intercellular adhesion proteins
|
icaB
|
0.0010028 |
12 |
VF0014
|
Biofilm |
(icaR) ica operon transcriptional regulator IcaR [Intercellular adhesion proteins (VF0014) - Biofilm (VFC0271)] [Staphylococcus aureus subsp. aureus MW2]
|
|
BtaE
|
btaE
|
0.0000501 |
1 |
VF1342
|
Adherence |
(btaE) Trimeric autotransporter adhesin, YadA-like family protein [BtaE (VF1342) - Adherence (VFC0001)] [Brucella melitensis biovar Abortus 2308]
|
|
Hyaluronate lyase
|
hysA
|
0.0002006 |
4 |
VF0013
|
Exoenzyme |
(hysA) hyaluronate lyase precursor [Hyaluronate lyase (VF0013) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Isd
|
isdA
|
0.0017048 |
14 |
VF0015
|
Nutritional/Metabolic factor |
(harA) haptoglobin-binding heme uptake protein HarA [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
SigA
|
sigA/rpoV
|
0.0005014 |
10 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Yersiniabactin
|
ybtS
|
0.0068191 |
68 |
VF0136
|
Nutritional/Metabolic factor |
(irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
PVL
|
lukS-PV
|
0.0001003 |
2 |
VF0018
|
Exotoxin |
(lukS-PV) Panton-Valentine leukocidin chain S precursor [PVL (VF0018) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SpA
|
spa
|
0.0001003 |
2 |
VF0017
|
Exotoxin |
(spa) Immunoglobulin G binding protein A precursor [SpA (VF0017) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SDr
|
sdrE
|
0.0028079 |
32 |
VF0019
|
Adherence |
(sdrC) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
FnBPs
|
fnbA
|
0.0009527 |
13 |
VF0010
|
Adherence |
(fnbA) fibronectin-binding protein A [FnBPs (VF0010) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Ent
|
entF
|
0.0150421 |
271 |
VF0562
|
Nutritional/Metabolic factor |
(entD) enterochelin synthetase component D [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
OatA
|
oatA
|
0.0001003 |
2 |
VF0441
|
Immune modulation |
(oatA) peptidoglycan O-acetyltransferase [OatA (VF0441) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
|
|
LPS
|
KP1_RS17225
|
0.0191035 |
360 |
VF0561
|
Immune modulation |
(KP1_RS17230) glycosyltransferase [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Ybt
|
ybtS
|
0.0043622 |
56 |
VF0564
|
Nutritional/Metabolic factor |
(ybtE) yersiniabactin biosynthesis salycil-AMP ligase YbtE [Ybt (VF0564) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
TTSS (SPI-2 encode)
|
ssaD
|
0.0001003 |
2 |
VF0321
|
Effector delivery system |
(ssaD) type III secretion system outer MS ring protein SsaD [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Sal
|
iroN
|
0.0034095 |
55 |
VF0563
|
Nutritional/Metabolic factor |
(iroN) salmochelin receptor IroN [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Type I fimbriae
|
fimI
|
0.0029583 |
43 |
VF0566
|
Adherence |
(fimG) type 1 fimbrial minor component [Type I fimbriae (VF0566) - Adherence (VFC0001)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Capsule
|
kpsF
|
0.0004513 |
9 |
VF0323
|
Immune modulation |
(gmhA2) phosphoheptose isomerase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Lap
|
lap
|
0.0006518 |
11 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Aerobactin
|
iutA
|
0.0039611 |
51 |
VF0565
|
Nutritional/Metabolic factor |
(iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
hldE
|
0.0001003 |
2 |
VF0326
|
Immune modulation |
(hldE) bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase [LOS (VF0326) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
AcrAB
|
acrA
|
0.0192038 |
263 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Type 3 fimbriae
|
mrkI
|
0.0029583 |
37 |
VF0567
|
Biofilm |
(mrkC) fimbrial biogenesis outer membrane usher protein mrkC precursor [Type 3 fimbriae (VF0567) - Biofilm (VFC0271)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Hemolysin
|
hlyB
|
0.0001003 |
2 |
VF0207
|
Exotoxin |
(hlyB) Hemolysin B [Hemolysin (VF0207) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
|
|
T6SS
|
vgrG/tssI
|
0.0075211 |
75 |
VF0569
|
Effector delivery system |
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Capsule
|
rfbK1
|
0.0618231 |
1,113 |
VF0560
|
Immune modulation |
(KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Flagella
|
tsr
|
0.0003008 |
5 |
VF0430
|
Motility |
(tsr) methyl-accepting chemotaxis protein I [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
|
|
FupA
|
feoB
|
0.0003008 |
6 |
VF0550
|
Nutritional/Metabolic factor |
(feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
GGT
|
ggt
|
0.0004011 |
8 |
VF0553
|
Nutritional/Metabolic factor |
(ggt) gamma-glutamyltranspeptidase [GGT (VF0553) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
CdpA
|
cdpA
|
0.0001003 |
1 |
VF0432
|
Regulation |
(cdpA) cyclic di-GMP phosphodiesterase [CdpA (VF0432) - Regulation (VFC0301)] [Burkholderia pseudomallei K96243]
|
|
Biotin synthesis
|
bioB
|
0.0001003 |
2 |
VF0552
|
Nutritional/Metabolic factor |
(bioB) biotin synthase [Biotin synthesis (VF0552) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
BoaA
|
boaA
|
0.0001003 |
2 |
VF0434
|
Adherence |
(boaA) surface-exposed protein, autotransporter [BoaA (VF0434) - Adherence (VFC0001)] [Burkholderia pseudomallei K96243]
|
|
Capsule I
|
wcbL
|
0.0002006 |
4 |
VF0436
|
Immune modulation |
(wcbL) sugar kinase [Capsule I (VF0436) - Immune modulation (VFC0258)] [Burkholderia pseudomallei K96243]
|
|
ESX-1
|
espE
|
0.0000501 |
1 |
VF0315
|
Effector delivery system |
(espE) ESX-1 secretion-associated protein EspE [ESX-1 (VF0315) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Dot/Icm T4SS secreted effectors
|
LPG_RS11860
|
0.0001504 |
3 |
VF0798
|
Effector delivery system |
(LPG_RS11860) Dot/Icm type IV secretion system effector [Dot/Icm T4SS secreted effectors (VF0798) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
EtpA
|
etpB
|
0.0000501 |
1 |
VF0437
|
Adherence |
(etpB) two-partner secretion transporter EtpB [EtpA (VF0437) - Adherence (VFC0001)] [Escherichia coli O78:H11:K80 str. H10407]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0054653 |
92 |
VF0558
|
Nutritional/Metabolic factor |
(carA) carbamoyl phosphate synthase small subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
PanC/PanD
|
panC
|
0.0001003 |
2 |
VF0319
|
Nutritional/Metabolic factor |
(panC) pantothenate synthetase [PanC/PanD (VF0319) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
LAM
|
aftD
|
0.0000501 |
1 |
VF0318
|
Immune modulation |
(aftD) alpha-(1->3)-arabinofuranosyltransferase [LAM (VF0318) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
BfmRS
|
bfmS
|
2.0048135 |
19,937 |
VF0463
|
Regulation |
(bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU]
|
|
Type 1 fimbriae
|
fimI
|
0.0009025 |
16 |
VF0221
|
Adherence |
(fimF) FimF protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Pyocyanin
|
phzS
|
0.0002006 |
4 |
VF0100
|
Nutritional/Metabolic factor |
(phzS) flavin dependent hydroxylase PhzS [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Bap
|
bap
|
1.2241276 |
15,117 |
VF0462
|
Biofilm |
(bap) biofilm-associated protein [Bap (VF0462) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
P fimbriae
|
papC
|
0.0001003 |
2 |
VF0220
|
Adherence |
(papG) P pilus tip adhesin PapG [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Bacillibactin
|
dhbF
|
0.0002507 |
4 |
VF0586
|
Nutritional/Metabolic factor |
(dhbF) non-ribosomal peptide synthetase, DhbF [Bacillibactin (VF0586) - Nutritional/Metabolic factor (VFC0272)] [Bacillus cereus ATCC 10987]
|
|
TTSS
|
cdsN
|
0.0001003 |
2 |
VF0344
|
Effector delivery system |
(cdsN) Type III secretion system ATPase [TTSS (VF0344) - Effector delivery system (VFC0086)] [Chlamydia trachomatis D/UW-3/CX]
|
|
Capsule
|
galE
|
12.3617629 |
19,937 |
VF0465
|
Immune modulation |
(ACICU_RS00405) polysaccharide biosynthesis/export family protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Type 1 fimbriae
|
fimH
|
0.0005515 |
8 |
VF0102
|
Adherence |
(fimZ) DNA-binding response regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Vi antigen
|
tviC
|
0.1987064 |
3,942 |
VF0101
|
Immune modulation |
(tviB) Vi polysaccharide biosynthesis protein, UDP-N-acetylglucosamine (UPD-GlcNAc) 6-dehydrogenase TviB [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
OmpA
|
ompA
|
1.0031087 |
19,940 |
VF0464
|
Immune modulation |
(ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Acinetobactin
|
barA
|
22.6177798 |
19,927 |
VF0467
|
Nutritional/Metabolic factor |
(basA) acinetobactin biosynthesis protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
Alpha-Hemolysin
|
hlyB
|
0.0002507 |
5 |
VF0225
|
Exotoxin |
(hlyB) Hemolysin B [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
F1C fimbriae
|
focA
|
0.0000501 |
1 |
VF0224
|
Adherence |
(focA) F1C major fimbrial subunit precursor [F1C fimbriae (VF0224) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
LPS
|
lpsB
|
8.4197252 |
19,944 |
VF0466
|
Immune modulation |
(lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Agf
|
csgE
|
0.0000501 |
1 |
VF0103
|
Adherence |
(csgE) curli production assembly/transport protein CsgE [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuX
|
0.0004011 |
8 |
VF0227
|
Nutritional/Metabolic factor |
(chuT) periplasmic heme-binding protein ChuT [Chu (VF0227) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
MgtB
|
mgtB
|
0.0184015 |
358 |
VF0106
|
Nutritional/Metabolic factor |
(mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Phospholipase D
|
plcD
|
1.0047132 |
19,938 |
VF0469
|
Exotoxin |
(plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
CNF-1
|
cnf1
|
0.0000501 |
1 |
VF0226
|
Exotoxin |
(cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0226) - Exotoxin (VFC0235)] [Escherichia coli UTI89]
|
|
SlpA
|
slpA
|
0.0000501 |
1 |
VF0589
|
Adherence |
(slpA) cell surface protein (S-layer precursor protein) [SlpA (VF0589) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
PbpG
|
pbpG
|
1.0024067 |
19,937 |
VF0468
|
Immune modulation |
(pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
LplA1
|
lplA1
|
0.0000501 |
1 |
VF0347
|
Nutritional/Metabolic factor |
(lplA1) lipoate protein ligase [LplA1 (VF0347) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
Lpf
|
lpfC
|
0.0001504 |
3 |
VF0105
|
Adherence |
(lpfC) long polar fimbrial usher protein LpfC [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Aerobactin
|
iucB
|
0.0003008 |
3 |
VF0229
|
Nutritional/Metabolic factor |
(iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Enterobactin
|
entF
|
0.0019053 |
30 |
VF0228
|
Nutritional/Metabolic factor |
(entF) enterobactin synthase multienzyme complex component, ATP-dependent [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
SodCI
|
sodCI
|
0.0025572 |
51 |
VF0109
|
Stress survival |
(sodCI) Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) [SodCI (VF0109) - Stress survival (VFC0282)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Csu fimbriae
|
csuC
|
4.2506017 |
16,986 |
VF0461
|
Biofilm |
(csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
EF-Tu
|
tufA
|
2.8633674 |
19,834 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
FHbp
|
fHbp
|
0.0001003 |
1 |
VF0452
|
Immune modulation |
(fHbp) factor H binding protein [FHbp (VF0452) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
Colibactin
|
clbG
|
0.0016546 |
12 |
VF0573
|
Exotoxin |
(clbC) colibactin polyketide synthase ClbC [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
MtrCDE
|
mtrD
|
0.0006017 |
11 |
VF0451
|
Antimicrobial activity/Competitive advantage |
(mtrC) membrane fusion protein MtrC [MtrCDE (VF0451) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
Allantion utilization
|
allB
|
0.0007521 |
12 |
VF0572
|
Nutritional/Metabolic factor |
(allA) ureidoglycolate hydrolase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
KatA
|
katA
|
0.7402728 |
14,562 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
T4SS secreted effectors
|
CBU_1566
|
1.1223426 |
19,820 |
VF0696
|
Effector delivery system |
(CBU_1079) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
T2SS
|
gspD
|
0.0005014 |
6 |
VF0333
|
Effector delivery system |
(gspE) general secretion pathway protein E [T2SS (VF0333) - Effector delivery system (VFC0086)] [Shigella dysenteriae Sd197]
|
|
Invasin B/Ifp
|
invB/ifp
|
0.0000501 |
1 |
VF0574
|
Invasion |
(invB/ifp) invasin B protein, intimin family [Invasin B/Ifp (VF0574) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
MsrAB
|
msrA/B(pilB
|
0.0033594 |
59 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
AAFs
|
aafC
|
0.0000501 |
1 |
VF0214
|
Adherence |
(aafC) aggregative adherence fimbria II usher protein AafC [AAFs (VF0214) - Adherence (VFC0001)] [Escherichia coli O44:H18 042]
|
|
VAS T6SS
|
vasE
|
0.0000501 |
1 |
VF0335
|
Effector delivery system |
(vasE) type VI secretion system protein VasE [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
HSI-1
|
ppkA
|
0.0003008 |
6 |
VF0334
|
Effector delivery system |
(tagS) type VI secretion associated protein TagS, forming a stable inner membrane complex with TagT [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
MntABC
|
mntB
|
0.0000501 |
1 |
VF0455
|
Stress survival |
(mntB) Manganese transport system membrane protein MntB [MntABC (VF0455) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Adhesive fimbriae
|
cfaD/cfaE
|
0.0001003 |
2 |
VF0213
|
Adherence |
(cfaD/cfaE) minor pilin and initiator [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A]
|
|
T6SS
|
vgrG/tssI
|
0.0013037 |
11 |
VF0579
|
Effector delivery system |
(tssG) Type VI secretion system protein TssG [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
Type IV pili
|
pilT
|
0.0000501 |
1 |
VF0458
|
Adherence |
(pilT) type IV pilus twitching motility protein PilT [Type IV pili (VF0458) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
RecN
|
recN
|
0.0000501 |
1 |
VF0457
|
Stress survival |
(recN) DNA repair protein RecN [RecN (VF0457) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Dispersin
|
aatC
|
0.0001003 |
2 |
VF0215
|
Others |
(aatC) ATP-binding protein AatC [Dispersin (VF0215) - Others (VFC0346)] [Escherichia coli O44:H18 042]
|
|
RcsAB
|
rcsB
|
0.0005515 |
11 |
VF0571
|
Regulation |
(rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
FarAB
|
farB
|
0.0021059 |
42 |
VF0450
|
Antimicrobial activity/Competitive advantage |
(farA) fatty acid efflux system protein FarA [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
RmpA
|
rmpA2
|
0.0002006 |
4 |
VF0570
|
Regulation |
(rmpA2) regulator of mucoid phenotype RmpA2 [RmpA (VF0570) - Regulation (VFC0301)] [Klebsiella pneumoniae CG43]
|
|
Type IV pili
|
pilV
|
0.0001003 |
2 |
VF0401
|
Adherence |
(pilV) type IV pilus biogenesis protein PilV [Type IV pili (VF0401) - Adherence (VFC0001)] [Yersinia pseudotuberculosis IP 31758]
|
|
SinH
|
sinH
|
0.0000501 |
1 |
VF0400
|
Adherence |
(sinH) intimin-like protein [SinH (VF0400) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type VII secretion system
|
esaB
|
0.0025572 |
18 |
VF0403
|
Effector delivery system |
(esaB) type VII secretion system protein EsaB [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
PavB
|
pavB/pfbB
|
0.0000501 |
1 |
VF0524
|
Adherence |
(pavB/pfbB) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein B [PavB (VF0524) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
ESX-5
|
PE18
|
0.0000501 |
1 |
VF0402
|
Effector delivery system |
(PE18) PE family protein PE18 [ESX-5 (VF0402) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
ECP
|
ykgK/ecpR
|
0.002156 |
34 |
VF0404
|
Adherence |
(ykgK/ecpR) regulator protein EcpR [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
AI-2
|
luxS
|
0.0004011 |
8 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Porin
|
porB
|
0.0000501 |
1 |
VF0081
|
Invasion |
(porB) major outer membrane protein PIB [Porin (VF0081) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
IgA1 protease
|
iga
|
0.0001504 |
1 |
VF0080
|
Effector delivery system |
(iga) IgA-specific serine endopeptidase [IgA1 protease (VF0080) - Effector delivery system (VFC0086)] [Neisseria meningitidis MC58]
|
|
TTSS
|
pscL
|
0.0001504 |
3 |
VF0083
|
Effector delivery system |
(exsC) type III secretion system regulatory protein ExsC [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Type IV pili
|
fimV
|
0.0063678 |
107 |
VF0082
|
Adherence |
(pilR) two-component response regulator PilR [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
PA3142
|
0.4764842 |
4,690 |
VF0085
|
Immune modulation |
(hisF2) imidazole glycerol phosphate synthase subunit HisF [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
Xcp secretion system
|
xcpR
|
0.0001504 |
3 |
VF0084
|
Effector delivery system |
(xcpZ) general secretion pathway protein M [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
LOS
|
rfaC
|
0.0002006 |
1 |
VF0078
|
Immune modulation |
(rfaC) lipopolysaccharide heptosyltransferase I [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
SSLs
|
set24
|
0.0016045 |
11 |
VF0990
|
Exotoxin |
(set19) superantigen-like protein SSL4 [SSLs (VF0990) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
ctrC
|
0.0001003 |
1 |
VF0079
|
Immune modulation |
(ctrC) capsule polysaccharide export inner-membrane protein CtrC [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
IlpA
|
IlpA
|
0.0008022 |
16 |
VF0513
|
Adherence |
(IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016]
|
|
MAM7
|
mam7
|
0.0000501 |
1 |
VF0512
|
Adherence |
(mam7) multivalent adhesion molecule MAM7 [MAM7 (VF0512) - Adherence (VFC0001)] [Vibrio parahaemolyticus RIMD 2210633]
|
|
HemO cluster
|
ACICU_RS04565
|
7.743933 |
19,661 |
VF0636
|
Nutritional/Metabolic factor |
(ACICU_RS04580) TonB-dependent receptor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
Yst1 T2SS
|
yst1D
|
0.0000501 |
1 |
VF0635
|
Effector delivery system |
(yst1D) type II secretion system secretin GspD [Yst1 T2SS (VF0635) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
OmpU
|
ompU
|
0.0001003 |
2 |
VF0514
|
Adherence |
(ompU) outer membrane protein OmpU [OmpU (VF0514) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6]
|
|
Flagella
|
flrA
|
0.0002006 |
3 |
VF0519
|
Motility |
(flgI) flagellar P-ring protein precursor FlgI [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
ClpC
|
clpC
|
0.0031087 |
49 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Ami
|
ami
|
0.0000501 |
1 |
VF0071
|
Adherence |
(ami) autolysin amidase, adhesin [Ami (VF0071) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
1.2088849 |
19,928 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpE
|
clpE
|
0.0003008 |
6 |
VF0073
|
Stress survival |
(clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Type IV pili
|
pilG
|
0.0013037 |
13 |
VF0075
|
Adherence |
(pilC) pilus assembly protein [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
Staphylocoagulase
|
coa
|
0.0002006 |
3 |
VF0421
|
Exoenzyme |
(coa) staphylocoagulase precursor [Staphylocoagulase (VF0421) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
LPS
|
wbtM
|
0.0893502 |
1,715 |
VF0542
|
Immune modulation |
(wbtM) dTDP-D-glucose 4,6-dehydratase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
VWbp
|
vWbp
|
0.0001504 |
3 |
VF0420
|
Exoenzyme |
(vWbp) secreted von Willebrand factor-binding protein precursor [VWbp (VF0420) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
Sbi
|
sbi
|
0.0002006 |
4 |
VF0423
|
Immune modulation |
(sbi) IgG-binding protein SBI [Sbi (VF0423) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Nitrate reductase
|
narH
|
0.0008022 |
16 |
VF0302
|
Nutritional/Metabolic factor |
(narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
AdsA
|
adsA
|
0.0004513 |
8 |
VF0422
|
Immune modulation |
(adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
galE
|
1.0061673 |
19,930 |
VF0543
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
KatG
|
katG
|
0.000351 |
7 |
VF0303
|
Stress survival |
(katG) catalase-peroxidase [KatG (VF0303) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
SCI T6SS secreted effectors
|
treTu
|
0.0185519 |
369 |
VF1195
|
Effector delivery system |
(treTu) Rhs polymorphic toxin, ADP-ribosyltransferase, type VI ribosyltransferase effector targeting EF-Tu [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
RTX protein
|
frpA
|
0.0006518 |
11 |
VF0897
|
Adherence |
(frpA) iron-regulated protein FrpA [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
InhA
|
BAS_RS06430
|
0.0000501 |
1 |
VF0536
|
Exoenzyme |
(BAS_RS06430) immune inhibitor A [InhA (VF0536) - Exoenzyme (VFC0251)] [Bacillus anthracis str. Sterne]
|
|
Alginate
|
algI
|
0.0019053 |
31 |
VF0091
|
Biofilm |
(mucC) negative regulator for alginate biosynthesis MucB [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyoverdine
|
pvdE
|
0.0018051 |
30 |
VF0094
|
Nutritional/Metabolic factor |
(pvdA) L-ornithine N5-oxygenase PvdA [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Pyochelin
|
pchE
|
0.0001504 |
3 |
VF0095
|
Nutritional/Metabolic factor |
(pchE) dihydroaeruginoic acid synthetase PchE [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
RelA
|
relA
|
0.0000501 |
1 |
VF0287
|
Regulation |
(relA) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) [RelA (VF0287) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
IgA1 protease
|
iga1
|
0.0000501 |
1 |
VF0045
|
Exoenzyme |
(iga1) immunoglobin A1 protease [IgA1 protease (VF0045) - Exoenzyme (VFC0251)] [Haemophilus influenzae Rd KW20]
|
|
LOS
|
rffG
|
1.1008825 |
19,931 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
KatAB
|
katA
|
0.01073 |
174 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
HmbR
|
hmbR
|
0.0001003 |
1 |
VF0048
|
Nutritional/Metabolic factor |
(hmbR) hemoglobin receptor [HmbR (VF0048) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
SodB
|
sodB
|
1.1401925 |
19,922 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Curli fibers
|
csgC
|
0.0004513 |
7 |
VF1138
|
Adherence |
(cgsE) curli production assembly/transport protein CsgE [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
|
|
T4P
|
pilQ
|
0.0001003 |
2 |
VF0966
|
Invasion |
(pilQ) Flp pilus assembly complex ATPase component TadA [T4P (VF0966) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
ChiRP
|
pilA
|
0.0001504 |
3 |
VF0609
|
Adherence |
(pilA) pilin [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Flagellar glycosylation/Pse biosynthetic pathway
|
pseB
|
0.0000501 |
1 |
VF0608
|
Motility |
(pseB) UDP-N-acetylglucosamine 4,6-dehydratase [Flagellar glycosylation/Pse biosynthetic pathway (VF0608) - Motility (VFC0204)] [Helicobacter pylori 26695]
|
|
FeoAB
|
feoB
|
0.0001003 |
2 |
VF0160
|
Nutritional/Metabolic factor |
(feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Type IV pili
|
pilT
|
0.0001504 |
3 |
VF0155
|
Adherence |
(pilT) type IV pilus twitching motility protein PilT [Type IV pili (VF0155) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
MisL
|
misL
|
0.0001003 |
2 |
VF0397
|
Adherence |
(misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LPS
|
bplL
|
0.000702 |
14 |
VF0033
|
Immune modulation |
(bplL) lipopolysaccharide biosynthesis protein [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
Mig-5
|
mig-5
|
0.0000501 |
1 |
VF0396
|
Antimicrobial activity/Competitive advantage |
(mig-5) putative carbonic anhydrase [Mig-5 (VF0396) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Lsp T2SS
|
lspG
|
0.0000501 |
1 |
VF0154
|
Effector delivery system |
(lspG) general secretion pathway protein G [Lsp T2SS (VF0154) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Flagella
|
LPG_RS02380
|
0.0010529 |
21 |
VF0157
|
Motility |
(fleQ) transcriptional regulator FleQ [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
RatB
|
ratB
|
0.0000501 |
1 |
VF0399
|
Adherence |
(ratB) putative outer membrane protein [RatB (VF0399) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
MgtC
|
mgtC
|
0.0000501 |
1 |
VF1365
|
Nutritional/Metabolic factor |
(mgtC) Salmonella virulence protein MgtC [MgtC (VF1365) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ShdA
|
shdA
|
0.0000501 |
1 |
VF0398
|
Adherence |
(shdA) AIDA autotransporter-like protein [ShdA (VF0398) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Hsp60
|
htpB
|
1.0140393 |
19,936 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Beta-haemolysin/cytolysin
|
cylG
|
0.0001003 |
2 |
VF0279
|
Exotoxin |
(cylG) 3-ketoacyl-ACP-reductase CylG [Beta-haemolysin/cytolysin (VF0279) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
|
|
Hgp
|
hgpC
|
0.0000501 |
1 |
VF0270
|
Nutritional/Metabolic factor |
(hgpC) hemoglobin-binding protein [Hgp (VF0270) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
O-antigen
|
YE_RS15425
|
0.0004011 |
8 |
VF0392
|
Immune modulation |
(YE_RS15425) GDP-L-fucose synthase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Capsule
|
GBS_RS06565
|
0.0001003 |
2 |
VF0274
|
Immune modulation |
(GBS_RS06565) glycosyltransferase [Capsule (VF0274) - Immune modulation (VFC0258)] [Streptococcus agalactiae NEM316]
|
|
Mig-14
|
mig-14
|
0.0000501 |
1 |
VF0395
|
Antimicrobial activity/Competitive advantage |
(mig-14) antimicrobial peptide resistance protein Mig-14 [Mig-14 (VF0395) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Flagella
|
motB
|
0.0038608 |
44 |
VF0394
|
Motility |
(fliL) flagellar basal body protein FliL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Flagella
|
fliE
|
0.0009527 |
18 |
VF0273
|
Motility |
(fleR) two-component response regulator [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
|
|
AdeFGH efflux pump
|
adeG
|
4.0579122 |
19,934 |
VF0504
|
Biofilm |
(adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
FdeC
|
fdeC
|
0.000351 |
5 |
VF0506
|
Adherence |
(fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
|
|
MprAB
|
mprA
|
0.0000501 |
1 |
VF0298
|
Regulation |
(mprA) two-component response regulator MrpA [MprAB (VF0298) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
LPS
|
rfbD
|
0.0001003 |
2 |
VF0056
|
Immune modulation |
(rfbD) GDP-D-mannose dehydratase [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
Ysa TTSS
|
ysaU
|
0.0000501 |
1 |
VF1025
|
Effector delivery system |
(ysaU) EscU/YscU/HrcU family type III secretion system export apparatus switch protein [Ysa TTSS (VF1025) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
BapA
|
bapA
|
0.0001003 |
2 |
VF0971
|
Adherence |
|
|
SiiE
|
siiE
|
0.0000501 |
1 |
VF0970
|
Adherence |
(siiE) non-fimbrial adhesin SiiE [SiiE (VF0970) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Flp pili
|
VV1_RS15610
|
0.0000501 |
1 |
VF0612
|
Adherence |
(VV1_RS15610) CpaF family protein [Flp pili (VF0612) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6]
|
|
TTSS secreted effectors
|
exoU
|
0.0002507 |
3 |
VF0853
|
Effector delivery system |
(exoT) type III secretion system effector ExoT, ADP ribosyltransferase activity and GTPase-activating protein activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
STM0287
|
0.0001003 |
2 |
VF0974
|
Effector delivery system |
|
|
Eps T2SS
|
epsE
|
0.0001003 |
2 |
VF0613
|
Effector delivery system |
(epsE) type II secretion system ATPase GspE [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395]
|
|
TTSS secreted effectors
|
ipaH9.8
|
0.0004513 |
2 |
VF0978
|
Effector delivery system |
(ospD2) type III secretion system effector OspD2 [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301]
|
|
CcmC
|
ccmE
|
0.0001003 |
2 |
VF0292
|
Nutritional/Metabolic factor |
(ccmE) cytochrome c-type biogenesis protein CcmE, heme chaperone [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
rfbC
|
0.0006518 |
13 |
VF0171
|
Immune modulation |
(LPG_RS03775) NAD-dependent epimerase/dehydratase family protein [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureG
|
2.0223626 |
19,932 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
EspC
|
espC
|
0.0000501 |
1 |
VF0173
|
Effector delivery system |
(espC) Type III secretion system secreted protein, serine protease [EspC (VF0173) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
TTSS secreted effectors
|
yopT
|
0.0001003 |
1 |
VF1021
|
Effector delivery system |
(yopT) type III secretion system effector YopT, cysteine protease [TTSS secreted effectors (VF1021) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
Flagella
|
fliA
|
0.0001504 |
3 |
VF0051
|
Motility |
(tlpA) membrane-bound chemoreceptor sensing arginine and bicarbonate [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]
|
|
SigE
|
sigE
|
0.0000501 |
1 |
VF0295
|
Regulation |
(sigE) ECF RNA polymerase sigma factor SigE [SigE (VF0295) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|